Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice (Q30486668)

18 August 2017

Up-regulating BDNF with an ampakine rescues synaptic plasticity and memory in Huntington's disease knockin mice (English)

1 reference

18 August 2017

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1 reference

7

Gary Lynch

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18 August 2017

6

Christine M Gall

1 reference

18 August 2017

Danielle A Simmons

1

1 reference

18 August 2017

Christopher S Rex

2

1 reference

18 August 2017

Linda Palmer

3

1 reference

18 August 2017

Vijay Pandyarajan

4

1 reference

18 August 2017

Vadim Fedulov

5

1 reference

18 August 2017

language of work or name

English

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publication date

5 March 2009

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Proceedings of the National Academy of Sciences of the United States of America

18 August 2017

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18 August 2017

106

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18 August 2017

4906-4911

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18 August 2017

12

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Altered dendritic integration in hippocampal granule cells of spatial learning-impaired aged rats

18 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Brain-derived neurotrophic factor restores synaptic plasticity in a knock-in mouse model of Huntington's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Role of brain-derived neurotrophic factor in Huntington's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

LTP consolidation: substrates, explanatory power, and functional significance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Restoration of long-term potentiation in middle-aged hippocampus after induction of brain-derived neurotrophic factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Integrin-driven actin polymerization consolidates long-term potentiation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Glutamate-based therapeutic approaches: ampakines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Facilitation of task performance and removal of the effects of sleep deprivation by an ampakine (CX717) in nonhuman primates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

BDNF function in adult synaptic plasticity: the synaptic consolidation hypothesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Spatial memory, recognition memory, and the hippocampus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Profile of cognitive progression in early Huntington's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Chronic elevation of brain-derived neurotrophic factor by ampakines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Pro-brain-derived neurotrophic factor is decreased in parietal cortex in Alzheimer's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Subtle changes among presymptomatic carriers of the Huntington's disease gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Positive modulation of AMPA receptors increases neurotrophin expression by hippocampal and cortical neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Impaired synaptic plasticity in mice carrying the Huntington's disease mutation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Evidence for specific cognitive deficits in preclinical Huntington's disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Effects of amygdaloid and amygdaloid-hippocampal lesions on object recognition and spatial working memory in rats.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Cognitive changes in patients with Huntington's disease (HD) and asymptomatic carriers of the HD mutation--a longitudinal follow-up study

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Cognitive dysfunction precedes neuropathology and motor abnormalities in the YAC128 mouse model of Huntington's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Brain-derived neurotrophic factor promotes long-term potentiation-related cytoskeletal changes in adult hippocampus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Reduced expression of the TrkB receptor in Huntington's disease mouse models and in human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

A novel mechanism for the facilitation of theta-induced long-term potentiation by brain-derived neurotrophic factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Evidence that long-term potentiation occurs within individual hippocampal synapses during learning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

D-Serine and a glycine transporter inhibitor improve MK-801-induced cognitive deficits in a novel object recognition test in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Enhancement by an ampakine of memory encoding in humans.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Dopamine-dependent long term potentiation in the dorsal striatum is reduced in the R6/2 mouse model of Huntington's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Locomotor exercise alters expression of pro-brain-derived neurotrophic factor, brain-derived neurotrophic factor and its receptor TrkB in the spinal cord of adult rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0811228106

Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

A YAC mouse model for Huntington's disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2660722

26 November 2018

Identifiers

DOI

10.1073/PNAS.0811228106

1 reference

18 August 2017

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18 August 2017

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