Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q (Q30486850)

18 August 2017

Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q (English)

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genome-wide association study

18 August 2017

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23

Gail P Jarvik

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Darren A Cusanovich

Darren Cusanovich

6

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Alex S Nord

Alex S Nord

2

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Dan L. Nicolae

Dan L Nicolae

25

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Carole Ober

1

Carole Ober

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18 August 2017

22

Santica Marcovina

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18 August 2017

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Deborah A Nickerson

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18 August 2017

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Raluca Nicolae

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Christine Billstrand

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Mark Abney

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Thomas S Hatsukami

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18 August 2017

Emma E Thompson

3

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18 August 2017

Lin Pan

4

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18 August 2017

Zheng Tan

5

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18 August 2017

Ying Sun

7

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18 August 2017

Celina Edelstein

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18 August 2017

Daniel H Schneider

10

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Ditta Pfaffinger

12

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18 August 2017

Natasha Phillips

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18 August 2017

Rebecca L Anderson

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Binu Philips

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18 August 2017

Ramakrishnan Rajagopalan

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18 August 2017

Mark J Rieder

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18 August 2017

Patrick J Heagerty

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Angelo M Scanu

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18 August 2017

5 January 2009

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Journal of Lipid Research

18 August 2017

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50

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5

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18 August 2017

798-806

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describes a project that uses

18 August 2017

genome-wide association study

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LPA and PLG sequence variation and kringle IV-2 copy number in two populations

inferred from title

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Niacin and lipoprotein(a): facts, uncertainties, and clinical considerations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Genetics of the Lp(a)/apo(a) system in an autochthonous Black African population from the Gabon

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Testing for Hardy-Weinberg equilibrium in samples with related individuals

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Lipoprotein(a): an elusive cardiovascular risk factor

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

The genetic dissection of complex traits in a founder population

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Broad and narrow heritabilities of quantitative traits in a founder population

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Single nucleotide polymorphisms in exons of the apo(a) kringles IV types 6 to 10 domain affect Lp(a) plasma concentrations and have different patterns in Africans and Caucasians

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Estimation of variance components of quantitative traits in inbred populations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

A multilocus genotyping assay for candidate markers of cardiovascular disease risk

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

A novel kringle-4 number-based recombinant apo[a] standard for human apo[a] phenotyping.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Characterization of multiple enhancer regions upstream of the apolipoprotein(a) gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

The Apo(a) gene is the major determinant of variation in plasma Lp(a) levels in African Americans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

The number of identical kringle IV repeats in apolipoprotein(a) affects its processing and secretion by HepG2 cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Identification of the cysteine residue in apolipoprotein(a) that mediates extracellular coupling with apolipoprotein B-100.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Genetic variation in lipoprotein (a) levels in families enriched for coronary artery disease is determined almost entirely by the apolipoprotein (a) gene locus.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

cDNA sequence of human apolipoprotein(a) is homologous to plasminogen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Genetic linkage between lipoprotein(a) phenotype and a DNA polymorphism in the plasminogen gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Lp(a) glycoprotein phenotypes. Inheritance and relation to Lp(a)-lipoprotein concentrations in plasma

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Changes of genetic apolipoprotein phenotypes caused by liver transplantation. Implications for apolipoprotein synthesis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Effects of the apolipoprotein(a) size polymorphism on the lipoprotein(a) concentration in 7 ethnic groups

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

The apolipoprotein (a) gene: a transcribed hypervariable locus controlling plasma lipoprotein (a) concentration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Genetic control of lipoprotein(a) concentrations is different in Africans and Caucasians

20 June 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Apo[a] size and PNR explain African American-Caucasian differences in allele-specific apo[a] levels for small but not large apo[a].

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Highly parallel SNP genotyping

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Significant impact of the +93 C/T polymorphism in the apolipoprotein(a) gene on Lp(a) concentrations in Africans but not in Caucasians: confounding effect of linkage disequilibrium

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Best linear unbiased allele-frequency estimation in complex pedigrees.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M800515-JLR200

Relation between number of apolipoprotein(a) kringle 4 repeats and mobility of isoforms in agarose gel: basis for a standardized isoform nomenclature.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2666166

Sequence and functional changes in a putative enhancer region upstream of the apolipoprotein(a) gene

26 November 2018

1 reference

12 December 2020

Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between American blacks and whites

1 reference

12 December 2020

Effect of the number of apolipoprotein(a) kringle 4 domains on immunochemical measurements of lipoprotein(a)

1 reference

12 December 2020

Influence of allelic variation on apolipoprotein(a) folding in the endoplasmic reticulum

1 reference

12 December 2020

TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects

1 reference

12 December 2020

Are common disease susceptibility alleles the same in outbred and founder populations?

1 reference

12 December 2020

10.1194/JLR.M800515-JLR200

Identifiers

DOI

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18 August 2017

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18 August 2017

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