The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study (Q30487287)

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English	The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study	scientific article

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scholarly article

1 reference

Europe PubMed Central

18 August 2017

The ErbB inhibitors trastuzumab and erlotinib inhibit growth of vestibular schwannoma xenografts in nude mice: a preliminary study (English)

1 reference

Europe PubMed Central

18 August 2017

1 reference

based on heuristic

inferred from title

vestibular schwannoma

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

J Jason Clark

1

1 reference

Europe PubMed Central

18 August 2017

Matthew Provenzano

2

1 reference

Europe PubMed Central

18 August 2017

Henry R Diggelmann

3

1 reference

Europe PubMed Central

18 August 2017

Ningyong Xu

4

1 reference

Europe PubMed Central

18 August 2017

Skylar S Hansen

5

1 reference

Europe PubMed Central

18 August 2017

Marlan R Hansen

6

1 reference

Europe PubMed Central

18 August 2017

publication date

1 September 2008

1 reference

Europe PubMed Central

18 August 2017

Otology & Neurotology

1 reference

Europe PubMed Central

18 August 2017

29

1 reference

Europe PubMed Central

18 August 2017

6

1 reference

Europe PubMed Central

18 August 2017

846-853

1 reference

Europe PubMed Central

18 August 2017

Lipid raft localization of ErbB2 in vestibular schwannoma and schwann cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Molecular studies of vestibular schwannomas: a review.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Targeting HER proteins in cancer therapy and the role of the non-target HER3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Management of acoustic neuromas in patients 65 years or older

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Erlotinib directly inhibits HER2 kinase activation and downstream signaling events in intact cells lacking epidermal growth factor receptor expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Oncolytic HSV and erlotinib inhibit tumor growth and angiogenesis in a novel malignant peripheral nerve sheath tumor xenograft model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Merlin/neurofibromatosis type 2 suppresses growth by inhibiting the activation of Ras and Rac.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

News on the genetics, epidemiology, medical care and translational research of Schwannomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Growth of benign and malignant schwannoma xenografts in severe combined immunodeficiency mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Antitumor effect of trastuzumab for pancreatic cancer with high HER-2 expression and enhancement of effect by combined therapy with gemcitabine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Comparison of growth patterns of acoustic neuromas with and without radiosurgery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Small acoustic neuromas: surgical outcomes versus observation or radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Mixed-lineage kinase 3 regulates B-Raf through maintenance of the B-Raf/Raf-1 complex and inhibition by the NF2 tumor suppressor protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

The molecular biology of vestibular schwannomas: dissecting the pathogenic process at the molecular level

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Merlin inhibits growth hormone-regulated Raf-ERKs pathways by binding to Grb2 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

The Phosphorylation status of merlin is important for regulating the Ras-ERK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

In vitro and in vivo effects of combination of Trastuzumab (Herceptin) and Tamoxifen in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Malignant transformation and new primary tumours after therapeutic radiation for benign disease: substantial risks in certain tumour prone syndromes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Stereotactic radiosurgery, microsurgery, and expectant management of acoustic neuroma: basis for informed consent

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Conservative management of acoustic neuroma: a meta-analysis and proposed treatment algorithm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Neurofibromatosis 2 (NF2) tumor suppressor merlin inhibits phosphatidylinositol 3-kinase through binding to PIKE-L

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Review of epidermal growth factor receptor biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

A clue to the therapy of neurofibromatosis type 2: NF2/merlin is a PAK1 inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Overexpression of the NF2 gene inhibits schwannoma cell proliferation through promoting PDGFR degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Merlin suppresses the SRE-dependent transcription by inhibiting the activation of Ras-ERK pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Detection of spontaneous schwannomas by MRI in a transgenic murine model of neurofibromatosis type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Malignancy in a vestibular schwannoma. Report of a case with central neurofibromatosis, treated by both stereotactic radiosurgery and surgical excision, with a review of the literature

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Mouse models of neurofibromatosis 1 and 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Conditional biallelic Nf2 mutation in the mouse promotes manifestations of human neurofibromatosis type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Role of neuregulins in glial cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Report of 190 consecutive cases of large acoustic tumors (vestibular schwannoma) removed via the translabyrinthine approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Mice heterozygous for a mutation at the Nf2 tumor suppressor locus develop a range of highly metastatic tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Universal absence of merlin, but not other ERM family members, in schwannomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Alteration in a new gene encoding a putative membrane-organizing protein causes neuro-fibromatosis type 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

Growth of human schwannomas in the subrenal capsule of the nude mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

20 June 2018

ErbB and Nrg: potential molecular targets for vestibular schwannoma pharmacotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Expression of ErbB-1 and 2 in vestibular schwannomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Neuregulin growth factors and their ErbB receptors form a potential signaling network for schwannoma tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Constitutive neuregulin-1/ErbB signaling contributes to human vestibular schwannoma proliferation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Treatment of schwannomas with an oncolytic recombinant herpes simplex virus in murine models of neurofibromatosis type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Activation of the neuregulin-1/ErbB signaling pathway promotes the proliferation of neoplastic Schwann cells in human malignant peripheral nerve sheath tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Vestibular schwannoma growth rates in neurofibromatosis type 2 natural history consortium subjects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Expression of neuregulin and activation of erbB receptors in vestibular schwannomas: possible autocrine loop stimulation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Malignant transformation of a recurrent vestibular schwannoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Age at symptom onset and long-term survival in patients with neurofibromatosis Type 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Constitutive activation of the neuregulin-1/ErbB receptor signaling pathway is essential for the proliferation of a neoplastic Schwann cell line

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Paxillin binds schwannomin and regulates its density-dependent localization and effect on cell morphology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

NF2 gene in neurofibromatosis type 2 patients.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

A novel moesin-, ezrin-, radixin-like gene is a candidate for the neurofibromatosis 2 tumor suppressor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

National Institutes of Health Consensus Development Conference Statement on Acoustic Neuroma, December 11-13, 1991. The Consensus Development Panel

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Subcutaneous growth of human acoustic schwannomas in athymic nude mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2652856

26 November 2018

Phenotypic variability in two families with novel splice-site and frameshift NF2 mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Growth of human acoustic neuromas, neurofibromas and schwannomas in the subrenal capsule and sciatic nerve of the nude mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erlotinib antitumor activity in non-small cell lung cancer models is independent of HER1 and HER2 overexpression

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p75NTR and sortilin increase after facial nerve injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High resolution deletion analysis of constitutional DNA from neurofibromatosis type 2 (NF2) patients using microarray-CGH

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurofibromatosis 2

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Upregulation of the Rac1/JNK signaling pathway in primary human schwannoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/18636037

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1097/MAO.0B013E31817F7398

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

1 reference

Europe PubMed Central

18 August 2017

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