A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis. (Q30489730)

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6 February 2020

title

A key role for the integrin alpha2beta1 in experimental and developmental angiogenesis (English)

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6 February 2020

5

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6 February 2020

Renato V. Iozzo

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6 February 2020

author name string

James D San Antonio

1

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Jason J Zoeller

2

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6 February 2020

Kari Habursky

3

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6 February 2020

Kevin Turner

4

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6 February 2020

Michelle Burrows

6

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6 February 2020

Sungwook Choi

7

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6 February 2020

Sandeep Basra

8

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Joel S Bennett

9

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William F DeGrado

10

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6 February 2020

language of work or name

English

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publication date

21 August 2009

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The American Journal of Pathology

6 February 2020

published in

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volume

175

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issue

3

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page(s)

1338-1347

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describes a project that uses

6 February 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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Notch signalling limits angiogenic cell behaviour in developing zebrafish arteries

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Endorepellin, the C-terminal angiostatic module of perlecan, enhances collagen-platelet responses via the alpha2beta1-integrin receptor

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BMP-1/Tolloid-like metalloproteases process endorepellin, the angiostatic C-terminal fragment of perlecan

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen.

20 June 2018

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26 November 2018

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26 November 2018

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26 November 2018

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Two functional active conformations of the integrin {alpha}2{beta}1, depending on activation condition and cell type.

26 November 2018

1 reference

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Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation

26 November 2018

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The alpha2beta1 integrin inhibitor rhodocetin binds to the A-domain of the integrin alpha2 subunit proximal to the collagen-binding site

26 November 2018

1 reference

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Angiogenesis in collagen I requires alpha2beta1 ligation of a GFP*GER sequence and possibly p38 MAPK activation and focal adhesion disassembly

26 November 2018

1 reference

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Collagen I initiates endothelial cell morphogenesis by inducing actin polymerization through suppression of cyclic AMP and protein kinase A.

26 November 2018

1 reference

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Dissection of angiogenic signaling in zebrafish using a chemical genetic approach

26 November 2018

1 reference

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Integrin α2-Deficient Mice Develop Normally, Are Fertile, but Display Partially Defective Platelet Interaction with Collagen

26 November 2018

1 reference

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Integrin alpha2beta1 is required for regulation of murine wound angiogenesis but is dispensable for reepithelialization

26 November 2018

1 reference

12 December 2020

Convergence of distinct pathways to heart patterning revealed by the small molecule concentramide and the mutation heart-and-soul

1 reference

12 December 2020

Rhodocetin antagonizes stromal tumor invasion in vitro and other alpha2beta1 integrin-mediated cell functions

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12 December 2020

Angiogenic network formation in the developing vertebrate trunk

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12 December 2020

Rapid analysis of angiogenesis drugs in a live fluorescent zebrafish assay

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12 December 2020

An alpha 2 beta 1 integrin-dependent pinocytic mechanism involving intracellular vacuole formation and coalescence regulates capillary lumen and tube formation in three-dimensional collagen matrix

1 reference

12 December 2020

10.2353/AJPATH.2009.090234

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19700757%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19700757%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

19700757

1 reference