Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis. (Q30493524)

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English	Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis.	scientific article

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2 February 2020

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis (English)

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2 February 2020

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2 February 2020

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D Taliaz

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D E Dar

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A Zangen

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21 July 2009

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2 February 2020

Molecular Psychiatry

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2 February 2020

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2 February 2020

80-92

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2 February 2020

1

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2 February 2020

Deletion of TrkB in adult progenitors alters newborn neuron integration into hippocampal circuits and increases anxiety-like behavior

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TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment

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Selective loss of brain-derived neurotrophic factor in the dentate gyrus attenuates antidepressant efficacy

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Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants

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Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice.

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Causal relationship between stressful life events and the onset of major depression

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https://api.crossref.org/works/10.1038%2FMP.2009.67

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Stress inhibits the proliferation of granule cell precursors in the developing dentate gyrus.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.67

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Increased neurogenesis and the ectopic granule cells after intrahippocampal BDNF infusion in adult rats.

1 reference

https://api.crossref.org/works/10.1038%2FMP.2009.67

21 January 2018

Performance of heterozygous brain-derived neurotrophic factor knockout mice on behavioral analogues of anxiety, nociception, and depression.

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https://api.crossref.org/works/10.1038%2FMP.2009.67

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Repeated electrical stimulation of reward-related brain regions affects cocaine but not "natural" reinforcement.

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21 January 2018

Brain-derived neurotrophic factor (BDNF) is required for the enhancement of hippocampal neurogenesis following environmental enrichment.

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Stimulation of the ventral subiculum of the hippocampus evokes glutamate receptor-mediated changes in dopamine efflux in the rat nucleus accumbens.

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21 January 2018

Activation of the TrkB neurotrophin receptor is induced by antidepressant drugs and is required for antidepressant-induced behavioral effects.

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Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression.

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26 November 2018

Glutamatergic afferents from the hippocampus to the nucleus accumbens regulate activity of ventral tegmental area dopamine neurons.

1 reference

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Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments.

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BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors

1 reference

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Proliferation, differentiation, and survival of rat sensory neuron precursors in vitro require specific trophic factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19621014

12 December 2020

based on heuristic

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Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/19621014

12 December 2020

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Increased neurogenesis in a model of electroconvulsive therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19621014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication

1 reference

https://pubmed.ncbi.nlm.nih.gov/19621014

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/MP.2009.67

1 reference

Europe PubMed Central

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2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19621014%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19621014%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

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Springer Nature article ID

10.1038/mp.2009.67

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