Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway. (Q30493710)

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18 January 2020

title

Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway (English)

1 reference

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18 January 2020

1 reference

7

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18 January 2020

Jennifer Ellis Ward

6

1 reference

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18 January 2020

author name string

Jianru Shi

1

1 reference

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18 January 2020

Jian Guan

2

1 reference

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18 January 2020

Bingbing Jiang

3

1 reference

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18 January 2020

Daniel A Brenner

4

1 reference

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18 January 2020

Federica Del Monte

5

1 reference

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18 January 2020

Douglas B Sawyer

8

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18 January 2020

Marc J Semigran

9

1 reference

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18 January 2020

Thomas E Macgillivray

10

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18 January 2020

David C Seldin

11

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18 January 2020

Rodney Falk

12

1 reference

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18 January 2020

Ronglih Liao

13

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18 January 2020

language of work or name

English

0 references

publication date

11 February 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20150510%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

18 January 2020

published in

1 reference

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18 January 2020

volume

107

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18 January 2020

page(s)

4188-4193

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18 January 2020

issue

9

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Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction.

18 January 2020

cites work

1 reference

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Role of TAB1 in nitric oxide-induced p38 activation in insulin-producing cells

20 June 2018

1 reference

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Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors

20 June 2018

1 reference

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cGMP-dependent protein kinase type I inhibits TAB1-p38 mitogen-activated protein kinase apoptosis signaling in cardiac myocytes

20 June 2018

1 reference

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Determinants that control the specific interactions between TAB1 and p38alpha

20 June 2018

1 reference

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TAB-1 modulates intracellular localization of p38 MAP kinase and downstream signaling

20 June 2018

1 reference

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Diagnosis and management of the cardiac amyloidoses

20 June 2018

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Role of p38alpha MAPK in cardiac apoptosis and remodeling after myocardial infarction

20 June 2018

1 reference

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Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease

20 June 2018

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STRESS signaling pathways that modulate cardiac myocyte apoptosis

20 June 2018

1 reference

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Increased tau phosphorylation on mitogen-activated protein kinase consensus sites and cognitive decline in transgenic models for Alzheimer's disease and FTDP-17: evidence for distinct molecular processes underlying tau abnormalities

20 June 2018

1 reference

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Molecular mechanisms of amyloidosis

20 June 2018

1 reference

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Diverse mechanisms of myocardial p38 mitogen-activated protein kinase activation: evidence for MKK-independent activation by a TAB1-associated mechanism contributing to injury during myocardial ischemia

20 June 2018

1 reference

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Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases

20 June 2018

1 reference

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Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

20 June 2018

1 reference

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MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38alpha

20 June 2018

1 reference

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Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation

20 June 2018

1 reference

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20 June 2018

The systemic amyloidoses

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Amyloid peptides are toxic via a common oxidative mechanism

20 June 2018

1 reference

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AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart

20 June 2018

1 reference

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Human amyloidogenic light chains directly impair cardiomyocyte function through an increase in cellular oxidant stress.

26 November 2018

1 reference

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Glucose-6-phosphate dehydrogenase modulates cytosolic redox status and contractile phenotype in adult cardiomyocytes

26 November 2018

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26 November 2018

1 reference

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p38 kinase is activated in the Alzheimer's disease brain.

26 November 2018

1 reference

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Oxidative stress causes heart failure with impaired mitochondrial respiration

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20150510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Infusion of light chains from patients with cardiac amyloidosis causes diastolic dysfunction in isolated mouse hearts

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20150510

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0912263107

1 reference

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18 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20150510%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference