Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster (Q30495533)

19 October 2017

Essential role of ubiquitin and TSG101 protein in formation and function of the central supramolecular activation cluster (English)

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19 October 2017

4

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19 October 2017

Santosha Vardhana

1

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Kaushik Choudhuri

object named as

Kaushik Choudhuri

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2

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author name string

Rajat Varma

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3

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19 October 2017

language of work or name

English

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publication date

1 April 2010

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19 October 2017

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19 October 2017

32

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19 October 2017

4

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19 October 2017

531-540

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describes a project that uses

19 October 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2905630/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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ESCRT ubiquitin-binding domains function cooperatively during MVB cargo sorting

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T cell-dendritic cell immunological synapses contain TCR-dependent CD28-CD80 clusters that recruit protein kinase C theta

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The balance between T cell receptor signaling and degradation at the center of the immunological synapse is determined by antigen quality

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20 June 2018

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The stimulatory potency of T cell antigens is influenced by the formation of the immunological synapse

20 June 2018

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Ultrastructural analysis of ESCRT proteins suggests a role for endosome-associated tubular-vesicular membranes in ESCRT function

20 June 2018

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T cell receptor-proximal signals are sustained in peripheral microclusters and terminated in the central supramolecular activation cluster

20 June 2018

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Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains

20 June 2018

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Distinct roles for Tsg101 and Hrs in multivesicular body formation and inward vesiculation

20 June 2018

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The ESCRT-III subunit hVps24 is required for degradation but not silencing of the epidermal growth factor receptor.

20 June 2018

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Two different stages of epidermal growth factor (EGF) receptor endocytosis are sensitive to free ubiquitin depletion produced by proteasome inhibitor MG132.

20 June 2018

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Actin and agonist MHC-peptide complex-dependent T cell receptor microclusters as scaffolds for signaling

20 June 2018

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Essential role of Hrs in a recycling mechanism mediating functional resensitization of cell signaling.

20 June 2018

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Engaged and bystander T cell receptors are down-modulated by different endocytotic pathways

20 June 2018

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Structural insights into endosomal sorting complex required for transport (ESCRT-I) recognition of ubiquitinated proteins.

20 June 2018

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Linking molecular and cellular events in T-cell activation and synapse formation

20 June 2018

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Vps27-Hse1 and ESCRT-I complexes cooperate to increase efficiency of sorting ubiquitinated proteins at the endosome.

20 June 2018

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T-cell receptor signal transmission: who gives an ITAM?

20 June 2018

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AIP1/ALIX Is a Binding Partner for HIV-1 p6 and EIAV p9 Functioning in Virus Budding

20 June 2018

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Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes

20 June 2018

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Vps27 recruits ESCRT machinery to endosomes during MVB sorting

20 June 2018

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STAM and Hrs are subunits of a multivalent ubiquitin-binding complex on early endosomes

20 June 2018

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c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation

20 June 2018

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T cell receptor ligation induces the formation of dynamically regulated signaling assemblies

20 June 2018

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CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse

20 June 2018

1 reference

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Structure and functional interactions of the Tsg101 UEV domain

20 June 2018

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Hrs sorts ubiquitinated proteins into clathrin-coated microdomains of early endosomes

20 June 2018

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Protein kinase C(theta) in T cell activation

20 June 2018

1 reference

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FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes

20 June 2018

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On the dynamics of TCR:CD3 complex cell surface expression and downmodulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Differential clustering of CD4 and CD3zeta during T cell recognition

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Membrane association and protein conformation of alpha-synuclein in intact neurons. Effect of Parkinson's disease-linked mutations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

The immunological synapse: a molecular machine controlling T cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

FRET microscopy demonstrates molecular association of non-specific lipid transfer protein (nsL-TP) with fatty acid oxidation enzymes in peroxisomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Three-dimensional segregation of supramolecular activation clusters in T cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Degradation of T cell receptor (TCR)-CD3-zeta complexes after antigenic stimulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Selective modulation of protein kinase C-theta during T-cell activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Opposing Effects of PKCθ and WASp on Symmetry Breaking and Relocation of the Immunological Synapse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Involvement of the conserved adaptor protein Alix in actin cytoskeleton assembly.

26 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Double-sided ubiquitin binding of Hrs-UIM in endosomal protein sorting

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Newly generated T cell receptor microclusters initiate and sustain T cell activation by recruitment of Zap70 and SLP-76.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Evidences for ubiquitination and intracellular trafficking of LAT, the linker of activated T cells

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Depletion of TSG101 forms a mammalian "Class E" compartment: a multicisternal early endosome with multiple sorting defects.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Ubiquitin recognition by the human TSG101 protein

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

T-cell-antigen recognition and the immunological synapse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

The immunological synapse balances T cell receptor signaling and degradation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

The immunological synapse

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2905630

Both clathrin-positive and -negative coats are involved in endosomal sorting of the EGF receptor

26 November 2018

1 reference

12 December 2020

Antigen activation of murine T cells induces tyrosine phosphorylation of a polypeptide associated with the T cell antigen receptor

1 reference

12 December 2020

Activation-induced ubiquitination of the T cell antigen receptor

1 reference

12 December 2020

Distinct roles for LFA-1 and CD28 during activation of naive T cells: adhesion versus costimulation

1 reference

12 December 2020

Serial TCR engagement and down-modulation by peptide:MHC molecule ligands: relationship to the quality of individual TCR signaling events

1 reference

12 December 2020

PKC-θ is required for TCR-induced NF-κB activation in mature but not immature T lymphocytes

1 reference

12 December 2020

10.1016/J.IMMUNI.2010.04.005

Identifiers

DOI

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

20399684

1 reference