Genetic targeting of ERK1 suggests a predominant role for ERK2 in murine pain models (Q30496403)

19 October 2017

Genetic targeting of ERK1 suggests a predominant role for ERK2 in murine pain models (English)

1 reference

19 October 2017

Benedict J Alter

1

1 reference

ORCID Public Data File 2021

author name string

Chengshui Zhao

2

1 reference

19 October 2017

Farzana Karim

3

1 reference

19 October 2017

Gary E Landreth

4

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19 October 2017

Robert W Gereau

5

1 reference

19 October 2017

language of work or name

English

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publication date

1 August 2010

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19 October 2017

11

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inferred from page(s)

published in

Journal of Neuroscience

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19 October 2017

30

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19 October 2017

34

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19 October 2017

11537-11547

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describes a project that uses

19 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2932641/fullTextXML

inferred from PubMed Central ID database lookup

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The N-terminal domain of ERK1 accounts for the functional differences with ERK2

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ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity.

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Mice lacking the ERK1 isoform of MAP kinase are unimpaired in emotional learning

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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14 July 2018

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ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

14 July 2018

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Extracellular signal-regulated kinase 2 (ERK2) knockdown mice show deficits in long-term memory; ERK2 has a specific function in learning and memory.

14 July 2018

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Activation of the extracellular signal-regulated kinase in the amygdala modulates pain perception.

26 November 2018

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Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons.

26 November 2018

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The kv4.2 potassium channel subunit is required for pain plasticity.

26 November 2018

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ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis.

26 November 2018

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ERK is sequentially activated in neurons, microglia, and astrocytes by spinal nerve ligation and contributes to mechanical allodynia in this neuropathic pain model

26 November 2018

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The contribution of autophosphorylated alpha-calcium-calmodulin kinase II to injury-induced persistent pain

26 November 2018

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Inflammation persistently enhances nocifensive behaviors mediated by spinal group I mGluRs through sustained ERK activation

26 November 2018

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Differential activation of extracellular signal-regulated protein kinase in primary afferent neurons regulates brain-derived neurotrophic factor expression after peripheral inflammation and nerve injury.

26 November 2018

1 reference

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Phosphorylation of extracellular signal-regulated kinase in primary afferent neurons by noxious stimuli and its involvement in peripheral sensitization.

26 November 2018

1 reference

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Knockout of ERK1 MAP kinase enhances synaptic plasticity in the striatum and facilitates striatal-mediated learning and memory

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932641

Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932641

The MAPK cascade is required for mammalian associative learning.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932641

Formalin-evoked activity in identified primary afferent fibers: systemic lidocaine suppresses phase-2 activity

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2932641

The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739576

12 December 2020

inferred from PubMed ID database lookup

Differential activation of MAPK in injured and uninjured DRG neurons following chronic constriction injury of the sciatic nerve in rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739576

12 December 2020

inferred from PubMed ID database lookup

Long-Lasting Inflammation and Long-Term Hyperalgesia After Subcutaneous Formalin Injection Into the Rat Hindpaw

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20739576

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1523/JNEUROSCI.6103-09.2010

1 reference

19 October 2017

1 reference

19 October 2017

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