p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation (Q30497179)

12 October 2017

p47phox Phox homology domain regulates plasma membrane but not phagosome neutrophil NADPH oxidase activation (English)

1 reference

12 October 2017

Xing Jun Li

1

1 reference

12 October 2017

Christophe C Marchal

2

1 reference

12 October 2017

Natalie D Stull

3

1 reference

12 October 2017

Robert V Stahelin

4

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12 October 2017

Mary C Dinauer

5

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12 October 2017

language of work or name

English

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publication date

5 September 2010

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Journal of Biological Chemistry

12 October 2017

11

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based on heuristic

inferred from page(s)

published in

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12 October 2017

285

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12 October 2017

45

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12 October 2017

35169-35179

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describes a project that uses

12 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2966130/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Cytosolic phospholipase A2alpha is targeted to the p47phox-PX domain of the assembled NADPH oxidase via a novel binding site in its C2 domain

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CD18-dependent activation of the neutrophil NADPH oxidase during phagocytosis of Escherichia coli or Staphylococcus aureus is regulated by class III but not class I or II PI3Ks

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Fc gamma R-stimulated activation of the NADPH oxidase: phosphoinositide-binding protein p40phox regulates NADPH oxidase activity after enzyme assembly on the phagosome

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Characterization of a mutation in the Phox homology domain of the NADPH oxidase component p40phox identifies a mechanism for negative regulation of superoxide production

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Gene transfer and expression in human neutrophils. The phox homology domain of p47phox translocates to the plasma membrane but not to the membrane of mature phagosomes

20 June 2018

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A regulated adaptor function of p40phox: distinct p67phox membrane targeting by p40phox and by p47phox

20 June 2018

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PtdIns3P binding to the PX domain of p40phox is a physiological signal in NADPH oxidase activation

20 June 2018

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The phosphoinositide-binding protein p40phox activates the NADPH oxidase during FcgammaIIA receptor-induced phagocytosis

20 June 2018

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Neutrophils from p40phox-/- mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing.

20 June 2018

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Small-angle X-ray scattering reveals an extended organization for the autoinhibitory resting state of the p47(phox) modular protein

20 June 2018

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Chronic granulomatous disease and other disorders of phagocyte function

20 June 2018

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A region C-terminal to the proline-rich core of p47phox regulates activation of the phagocyte NADPH oxidase by interacting with the C-terminal SH3 domain of p67phox

20 June 2018

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Activation and assembly of the NADPH oxidase: a structural perspective

20 June 2018

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20 June 2018

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The coordination of signaling during Fc receptor-mediated phagocytosis

20 June 2018

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Assembly of the phagocyte NADPH oxidase

20 June 2018

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Structure and regulation of the neutrophil respiratory burst oxidase: comparison with nonphagocyte oxidases

20 June 2018

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NOXO1, Regulation of Lipid Binding, Localization, and Activation of Nox1 by the Phox Homology (PX) Domain

20 June 2018

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Molecular basis of phosphorylation-induced activation of the NADPH oxidase

20 June 2018

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Phosphoinositide recognition domains

20 June 2018

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Phosphorylation of p47phox directs phox homology domain from SH3 domain toward phosphoinositides, leading to phagocyte NADPH oxidase activation

20 June 2018

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Membrane binding mechanisms of the PX domains of NADPH oxidase p40phox and p47phox

20 June 2018

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The adaptor protein p40(phox) as a positive regulator of the superoxide-producing phagocyte oxidase.

20 June 2018

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The superoxide-generating NADPH oxidase: structural aspects and activation mechanism

20 June 2018

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Binding of the PX domain of p47(phox) to phosphatidylinositol 3,4-bisphosphate and phosphatidic acid is masked by an intramolecular interaction

20 June 2018

1 reference

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Chronic granulomatous disease mutations and the PX domain

20 June 2018

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The PX domain: a new phosphoinositide-binding module

20 June 2018

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Architecture of the p40-p47-p67phox complex in the resting state of the NADPH oxidase. A central role for p67phox

20 June 2018

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The crystal structure of the PX domain from p40(phox) bound to phosphatidylinositol 3-phosphate

20 June 2018

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Distinct roles of class I and class III phosphatidylinositol 3-kinases in phagosome formation and maturation

20 June 2018

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Phoxy lipids: revealing PX domains as phosphoinositide binding modules

20 June 2018

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The PX domains of p47phox and p40phox bind to lipid products of PI(3)K

20 June 2018

1 reference

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Solution structure of the PX domain, a target of the SH3 domain

20 June 2018

1 reference

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Autosomal recessive chronic granulomatous disease caused by defects in NCF-1, the gene encoding the phagocyte p47-phox: mutations not arising in the NCF-1 pseudogenes

20 June 2018

1 reference

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Respiratory burst in human neutrophils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

Mechanism for phosphorylation-induced activation of the phagocyte NADPH oxidase protein p47(phox). Triple replacement of serines 303, 304, and 328 with aspartates disrupts the SH3 domain-mediated intramolecular interaction in p47(phox), thereby acti

20 June 2018

1 reference

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Functional modules and expression of mouse p40(phox) and p67(phox), SH3-domain-containing proteins involved in the phagocyte NADPH oxidase complex

20 June 2018

1 reference

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Enhanced host defense after gene transfer in the murine p47phox-deficient model of chronic granulomatous disease

20 June 2018

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Novel domains in NADPH oxidase subunits, sorting nexins, and PtdIns 3-kinases: binding partners of SH3 domains?

20 June 2018

1 reference

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Interactions between cytosolic components of the NADPH oxidase: p40phox interacts with both p67phox and p47phox

20 June 2018

1 reference

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Assembly and activation of the phagocyte NADPH oxidase. Specific interaction of the N-terminal Src homology 3 domain of p47phox with p22phox is required for activation of the NADPH oxidase

20 June 2018

1 reference

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Mechanisms of NADPH oxidase activation: translocation of p40phox, Rac1 and Rac2 from the cytosol to the membranes in human neutrophils lacking p47phox or p67phox

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

Multiple SH3 domain interactions regulate NADPH oxidase assembly in whole cells

20 June 2018

1 reference

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Receptor stimulated accumulation of phosphatidylinositol (3,4,5)-trisphosphate by G-protein mediated pathways in human myeloid derived cells.

20 June 2018

1 reference

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Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

The phosphorylation of the respiratory burst oxidase component p47phox during neutrophil activation. Phosphorylation of sites recognized by protein kinase C and by proline-directed kinases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

156Pro-->Gln substitution in the light chain of cytochrome b558 of the human NADPH oxidase (p22-phox) leads to defective translocation of the cytosolic proteins p47-phox and p67-phox

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

Assembly of the phagocyte NADPH oxidase: binding of Src homology 3 domains to proline-rich targets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

The p47phox mouse knock-out model of chronic granulomatous disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

Neutrophil nicotinamide adenine dinucleotide phosphate oxidase assembly. Translocation of p47-phox and p67-phox requires interaction between p47-phox and cytochrome b558.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2966130

Phosphorylation of p47phox sites by PKC alpha, beta II, delta, and zeta: effect on binding to p22phox and on NADPH oxidase activation

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

The p40phox and p47phox PX domains of NADPH oxidase target cell membranes via direct and indirect recruitment by phosphoinositides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

The PX domain as a novel phosphoinositide- binding module

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

The p47phox PX domain: two heads are better than one!

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

Rac GTPase isoform-specific regulation of NADPH oxidase and chemotaxis in murine neutrophils in vivo. Role of the C-terminal polybasic domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

Enhanced cutaneous inflammatory reactions to Aspergillus fumigatus in a murine model of chronic granulomatous disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

Crucial role of two potential cytosolic regions of Nox2, 191TSSTKTIRRS200 and 484DESQANHFAVHHDEEKD500, on NADPH oxidase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

Localised PtdIns(3,4,5)P3 or PtdIns(3,4)P2 at the phagocytic cup is required for both phagosome closure and Ca2+ signalling in HL60 neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.164475

21 January 2018

Identifiers

DOI

10.1074/JBC.M110.164475

1 reference

12 October 2017

1 reference

12 October 2017

PubMed publication ID

20817944

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