Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis (Q30497499)

30 September 2017

Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis (English)

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30 September 2017

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30 September 2017

Norbert Gerdes

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Alma Zernecke

2

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Alma Zernecke

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ORCID Public Data File 2021

30 September 2017

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Richard Flavell

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object named as

Richard A Flavell

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30 September 2017

Dirk Lievens

1

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30 September 2017

Tom Seijkens

3

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30 September 2017

Oliver Soehnlein

4

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30 September 2017

Linda Beckers

5

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30 September 2017

Imke C A Munnix

6

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30 September 2017

Erwin Wijnands

7

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30 September 2017

Pieter Goossens

8

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30 September 2017

Roger van Kruchten

9

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30 September 2017

Larissa Thevissen

10

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30 September 2017

Louis Boon

11

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30 September 2017

Randolph J Noelle

13

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30 September 2017

Erik A Biessen

15

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30 September 2017

Mat J A P Daemen

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30 September 2017

Johan W M Heemskerk

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30 September 2017

Esther Lutgens

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30 September 2017

language of work or name

English

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publication date

12 August 2010

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30 September 2017

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30 September 2017

116

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30 September 2017

4317-4327

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30 September 2017

20

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Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Immune and inflammatory mechanisms of atherosclerosis (*)

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Molecular and functional interactions among monocytes, platelets, and endothelial cells and their relevance for cardiovascular diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelet chemokines in vascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelets: inflammatory firebugs of vascular walls

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelets as immune cells: bridging inflammation and cardiovascular disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelets in inflammation and atherogenesis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelets and chemokines in atherosclerosis: partners in crime

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Role of platelets in the development of atherosclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Inhibition of NF-kappaB activation in macrophages increases atherosclerosis in LDL receptor-deficient mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

CD40 signaling and plaque instability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

The CD40/CD154 receptor/ligand dyad

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Reduction of atherosclerosis in mice by inhibition of CD40 signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelet-derived interleukin 1 induces human endothelial adhesion molecule expression and cytokine production

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Disrupting functional interactions between platelet chemokines inhibits atherosclerosis in hyperlipidemic mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Natural regulatory T cells control the development of atherosclerosis in mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Importance of Junctional Adhesion Molecule-A for Neointimal Lesion Formation and Infiltration in Atherosclerosis-Prone Mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

The glycoprotein VI-phospholipase Cgamma2 signaling pathway controls thrombus formation induced by collagen and tissue factor in vitro and in vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Gene profiling in atherosclerosis reveals a key role for small inducible cytokines: validation using a novel monocyte chemoattractant protein monoclonal antibody.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endothelium

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelet-monocyte complexes support monocyte adhesion to endothelium by enhancing secondary tethering and cluster formation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Platelet receptor interplay regulates collagen-induced thrombus formation in flowing human blood

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Complementary roles of glycoprotein VI and alpha2beta1 integrin in collagen-induced thrombus formation in flowing whole blood ex vivo

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Endothelial von Willebrand factor recruits platelets to atherosclerosis-prone sites in response to hypercholesterolemia

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Induction of rapid atherogenesis by perivascular carotid collar placement in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Requirement for CD154 in the progression of atherosclerosis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2993630

Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytes

26 November 2018

1 reference

12 December 2020

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice

1 reference

12 December 2020

CD40 ligand influences platelet release of reactive oxygen intermediates

1 reference

12 December 2020

Risk stratification of patients with acute myocardial infarction by quantification of circulating monocyte-platelet aggregates

1 reference

12 December 2020

Platelet-vessel wall interactions in atherosclerotic disease

1 reference

12 December 2020

Transendothelial migration drives dissociation of plateletmonocyte complexes

1 reference

12 December 2020

CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism

1 reference

12 December 2020

Platelet-derived CD40L: the switch-hitting player of cardiovascular disease

1 reference

12 December 2020

Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cells

1 reference

12 December 2020

Platelet activation in unstable coronary disease

1 reference

12 December 2020

Dynamics of leukocyte-platelet adhesion in whole blood

1 reference

12 December 2020

Collagen but not fibrinogen surfaces induce bleb formation, exposure of phosphatidylserine, and procoagulant activity of adherent platelets: evidence for regulation by protein tyrosine kinase-dependent Ca2+ responses

1 reference

12 December 2020

Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease

1 reference

12 December 2020

CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expression

1 reference

12 December 2020

10.1182/BLOOD-2010-01-261206

Identifiers

DOI

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30 September 2017

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30 September 2017

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