Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding (Q30497588)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736928%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

title

Gene delivery of a mutant TGFβ3 reduces markers of scar tissue formation after cutaneous wounding (English)

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11 February 2020

1

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11 February 2020

Suzanne M Buckley

5

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11 February 2020

Lynda Coughlan

6

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11 February 2020

David Gilham

7

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11 February 2020

author name string

Rachel Crossley

2

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11 February 2020

Vicky Sheard

3

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11 February 2020

Steven J Howe

4

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11 February 2020

Robert E Hawkins

8

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11 February 2020

Tristan R McKay

9

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11 February 2020

publication date

24 August 2010

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11 February 2020

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11 February 2020

volume

18

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11 February 2020

issue

12

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11 February 2020

page(s)

2104-2111

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Dermal transforming growth factor-beta responsiveness mediates wound contraction and epithelial closure

11 February 2020

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Tolerance induction using lentiviral gene delivery delays onset and severity of collagen II arthritis

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New therapeutics for the prevention and reduction of scarring

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Prevention and reduction of scarring in the skin by Transforming Growth Factor beta 3 (TGFbeta3): from laboratory discovery to clinical pharmaceutical

20 June 2018

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Doxorubicin inhibits TGF-beta signaling in human lung carcinoma A549 cells

20 June 2018

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Collagen membranes loaded with collagen-binding human PDGF-BB accelerate wound healing in a rabbit dermal ischemic ulcer model.

20 June 2018

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Smad3 deficiency alters key structural elements of the extracellular matrix and mechanotransduction of wound closure.

20 June 2018

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Smad transcription factors

20 June 2018

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Lentiviral transfection with the PDGF-B gene improves diabetic wound healing

20 June 2018

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Parallels between tissue repair and embryo morphogenesis

20 June 2018

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Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1.

20 June 2018

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Smad3 as a mediator of the fibrotic response

20 June 2018

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TGF-beta: a fibrotic factor in wound scarring and a potential target for anti-scarring gene therapy

20 June 2018

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Ontogenetic transition in fetal wound transforming growth factor-beta regulation correlates with collagen organization

20 June 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

20 June 2018

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Binding of TGF-beta1 latency-associated peptide (LAP) to alpha(v)beta6 integrin modulates behaviour of squamous carcinoma cells

20 June 2018

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Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter

20 June 2018

1 reference

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Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Effect of host modification and age on airway epithelial gene transfer mediated by a murine leukemia virus-derived vector

20 June 2018

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A third-generation lentivirus vector with a conditional packaging system

20 June 2018

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20 June 2018

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7 January 2021

inferred from DOI database lookup

Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Fibroblasts, myofibroblasts, and wound contraction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Recombinant latent transforming growth factor beta 1 has a longer plasma half-life in rats than active transforming growth factor beta 1, and a different tissue distribution

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Consequences of surgical stress on the kinetics of skin wound healing: partial hepatectomy delays and functionally alters dermal repair

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Efficient gene delivery to the adult and fetal CNS using pseudotyped non-integrating lentiviral vectors.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Lentiviral transduction of the murine lung provides efficient pseudotype and developmental stage-dependent cell-specific transgene expression

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

A novel truncated TGF-beta receptor II downregulates collagen synthesis and TGF-beta I secretion of keloid fibroblasts.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Mesenchymal stem cells enhance wound healing through differentiation and angiogenesis.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Intravenously injected human fibroblasts home to skin wounds, deliver type VII collagen, and promote wound healing

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

The temporal effects of anti-TGF-beta1, 2, and 3 monoclonal antibody on wound healing and hypertrophic scar formation.

26 November 2018

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Phylogenetic footprinting and genome scanning identify vertebrate BMP response elements and new target genes.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Adenoviral gene transfer allows Smad-responsive gene promoter analyses and delineation of type I receptor usage of transforming growth factor-beta family ligands in cultured human granulosa luteal cells.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Correction of multi-gene deficiency in vivo using a single 'self-cleaving' 2A peptide-based retroviral vector

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Acceleration of healing, reduction of fibrotic scar, and normalization of tissue architecture by an angiotensin analogue, NorLeu3-A(1-7).

26 November 2018

1 reference

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Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide

26 November 2018

1 reference

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Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow

26 November 2018

1 reference

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High-level transduction and gene expression in hematopoietic repopulating cells using a human immunodeficiency [correction of imunodeficiency] virus type 1-based lentiviral vector containing an internal spleen focus forming virus promoter

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

alpha v beta 6 Integrin upregulates matrix metalloproteinase 9 and promotes migration of normal oral keratinocytes

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Collagen-embedded platelet-derived growth factor DNA plasmid promotes wound healing in a dermal ulcer model

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2997585

Endogenous inflammatory response to dermal wound healing in the fetal and adult mouse.

26 November 2018

1 reference

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Abrogation of transforming growth factor-beta signaling by SMAD7 inhibits collagen gel contraction of human dermal fibroblasts

26 November 2018

1 reference

12 December 2020

Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma

1 reference

12 December 2020

TGF-beta1 antisense therapy modulates expression of matrix metalloproteinases in keloid-derived fibroblasts

1 reference

12 December 2020

The extracellular matrix of lip wounds in fetal, neonatal and adult mice

1 reference

12 December 2020

An assay for transforming growth factor-beta using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct

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12 December 2020

alpha 3A beta 1 integrin localizes to focal contacts in response to diverse extracellular matrix proteins

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12 December 2020

Identifiers

DOI

10.1038/MT.2010.174

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736928%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20736928%20AND%20SRC:MED&resulttype=core&format=json

11 February 2020

1 reference