Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors (Q30497637)

27 September 2017

Galantamine-induced amyloid-{beta} clearance mediated via stimulation of microglial nicotinic acetylcholine receptors (English)

1 reference

27 September 2017

0 references

1 reference

11

Shun Shimohama

1 reference

27 September 2017

1

Kazuyuki Takata

1 reference

27 September 2017

Yoshihisa Kitamura

2

1 reference

27 September 2017

Mana Saeki

3

1 reference

27 September 2017

Maki Terada

4

1 reference

27 September 2017

Sachiko Kagitani

5

1 reference

27 September 2017

Risa Kitamura

6

1 reference

27 September 2017

Yasuhiro Fujikawa

7

1 reference

27 September 2017

Alfred Maelicke

8

1 reference

27 September 2017

Hidekazu Tomimoto

9

1 reference

27 September 2017

Takashi Taniguchi

10

1 reference

27 September 2017

language of work or name

English

0 references

publication date

14 October 2010

1 reference

Journal of Biological Chemistry

27 September 2017

1 reference

27 September 2017

285

1 reference

27 September 2017

51

1 reference

27 September 2017

40180-40191

1 reference

Involvement of WAVE accumulation in Abeta/APP pathology-dependent tangle modification in Alzheimer's disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Amyloid-beta immunisation for Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Regulation of platelet Rac1 and Cdc42 activation through interaction with calmodulin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

The role of CaMKII as an F-actin-bundling protein crucial for maintenance of dendritic spine structure

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Effect of subchronic treatment of memantine, galantamine, and nicotine in the brain of Tg2576 (APPswe) transgenic mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Nicotine reduces A beta in the brain and cerebral vessels of APPsw mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Update on Alzheimer drugs (galantamine).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Involvement of Wiskott-Aldrich syndrome protein family verprolin-homologous protein (WAVE) and Rac1 in the phagocytosis of amyloid-beta(1-42) in rat microglia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Galantamine is an allosterically potentiating ligand of neuronal nicotinic but not of muscarinic acetylcholine receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Enhanced neurofibrillary degeneration in transgenic mice expressing mutant tau and APP.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Alzheimer's disease and related disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

alpha 7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block A beta-amyloid-induced neurotoxicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Allosteric sensitization of nicotinic receptors by galantamine, a new treatment strategy for Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Nicotinic receptor function: new perspectives from knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Translating cell biology into therapeutic advances in Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Choline is a selective agonist of alpha7 nicotinic acetylcholine receptors in the rat brain neurons.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Rho GTPases and the actin cytoskeleton

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Expression of two neuronal nicotinic receptor subunits in innervated and denervated adult rat muscle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

An evaluation of neuronal nicotinic acetylcholine receptor activation by quaternary nitrogen compounds indicates that choline is selective for the alpha 7 subtype.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Agonist and toxin sensitivities of ACh-evoked currents on neurons expressing multiple nicotinic ACh receptor subunits.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Alzheimer disease: Evidence for selective loss of cholinergic neurons in the nucleus basalis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Alzheimer's Disease: A Disorder of Cortical Cholinergic Innervation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

Selective loss of central cholinergic neurons in Alzheimer's disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Deglycosylated anti-amyloid beta antibodies reduce microglial phagocytosis and cytokine production while retaining the capacity to induce amyloid beta sequestration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Neuropathology of human Alzheimer disease after immunization with amyloid-beta peptide: a case report.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Galantamine in AD: A 6-month randomized, placebo-controlled trial with a 6-month extension. The Galantamine USA-1 Study Group.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

The cognitive benefits of galantamine are sustained for at least 36 months: a long-term extension trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Allosteric modulation of Torpedo nicotinic acetylcholine receptor ion channel activity by noncompetitive agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Allosteric modulation of nicotinic acetylcholine receptors as a treatment strategy for Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Galantamine modulates nicotinic receptor and blocks Abeta-enhanced glutamate toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Synergistic effect of galantamine on nicotine-induced neuroprotection in hemiparkinsonian rat model

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Cholinergic modulation of microglial activation by alpha 7 nicotinic receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Microglial alpha7 nicotinic acetylcholine receptors drive a phospholipase C/IP3 pathway and modulate the cell activation toward a neuroprotective role.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Microglial activation and amyloid-beta clearance induced by exogenous heat-shock proteins.

21 January 2018

2 references

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

21 January 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001000

High mobility group box protein-1 inhibits microglial Abeta clearance and enhances Abeta neurotoxicity

26 November 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Androgens modulate beta-amyloid levels in male rat brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Choline availability and acetylcholine synthesis in the hippocampus of acetylcholinesterase-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Chronic nicotine treatment reduces beta-amyloidosis in the brain of a mouse model of Alzheimer's disease (APPsw).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

IL-4-induced selective clearance of oligomeric beta-amyloid peptide(1-42) by rat primary type 2 microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.142356

Photoaffinity labeling of Torpedo acetylcholine receptor by physostigmine

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20947502

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Monoclonal antibodies FK1 and WF6 define two neighboring ligand binding sites on Torpedo acetylcholine receptor alpha-polypeptide

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20947502

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Agonist responses of neuronal nicotinic acetylcholine receptors are potentiated by a novel class of allosterically acting ligands

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20947502

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M110.142356

1 reference

27 September 2017

1 reference

27 September 2017

1 reference