Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis. (Q30501593)

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6 February 2020

title

Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis (English)

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6 February 2020

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12

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6 February 2020

Jessica Zambonin

1

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6 February 2020

Graham R Campbell

4

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6 February 2020

Josa M Frischer

9

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Douglass Matthew Turnbull

6 February 2020

10

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6 February 2020

Robin Franklin

13

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6 February 2020

author name string

Chao Zhao

2

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6 February 2020

Nobuhiko Ohno

3

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6 February 2020

Sarah Engeham

5

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6 February 2020

Iryna Ziabreva

6

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6 February 2020

Nadine Schwarz

7

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6 February 2020

Sok Ee Lee

8

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6 February 2020

Bruce D Trapp

11

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6 February 2020

Don J Mahad

14

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language of work or name

English

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publication date

1 July 2011

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6 February 2020

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6 February 2020

volume

134

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6 February 2020

issue

Pt 7

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6 February 2020

page(s)

1901-1913

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describes a project that uses

6 February 2020

ImageJ

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11 June 2022

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inferred from PubMed Central ID database lookup

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Demyelination increases axonal stationary mitochondrial size and the speed of axonal mitochondrial transport

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SLP-2 is required for stress-induced mitochondrial hyperfusion

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Mitochondrial changes within axons in multiple sclerosis

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Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

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Mitochondrial biogenesis in the axons of vertebrate peripheral neurons

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Remyelination protects axons from demyelination-associated axon degeneration

20 June 2018

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Remyelination can be extensive in multiple sclerosis despite a long disease course

20 June 2018

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Sodium channels and multiple sclerosis: roles in symptom production, damage and therapy.

20 June 2018

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Axonal protection in multiple sclerosis--a particular need during remyelination?

20 June 2018

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Remyelination is extensive in a subset of multiple sclerosis patients.

20 June 2018

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The axonal transport of mitochondria.

20 June 2018

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Molecular changes in neurons in multiple sclerosis: altered axonal expression of Nav1.2 and Nav1.6 sodium channels and Na+/Ca2+ exchanger

20 June 2018

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The effects of injecting 'energy-rich' phosphate compounds on the active transport of ions in the giant axons of Loligo

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The role of nitric oxide in multiple sclerosis

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Quantitative ultrastructural analysis of a single spinal cord demyelinated lesion predicts total lesion load, axonal loss, and neurological dysfunction in a murine model of multiple sclerosis

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Multiple sclerosis and chronic autoimmune encephalomyelitis: a comparative quantitative study of axonal injury in active, inactive, and remyelinated lesions

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Nodal, paranodal and juxtaparanodal axonal proteins during demyelination and remyelination in multiple sclerosis.

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Axonal loss in multiple sclerosis: a pathological survey of the corticospinal and sensory tracts

21 January 2018

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Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients

21 January 2018

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Disruption of neurofascin localization reveals early changes preceding demyelination and remyelination in multiple sclerosis

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Acute axonal damage in multiple sclerosis is most extensive in early disease stages and decreases over time.

21 January 2018

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Axonal mitochondrial transport and potential are correlated

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Na+-dependent sources of intra-axonal Ca2+ release in rat optic nerve during in vitro chemical ischemia.

21 January 2018

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Impaired remyelination and depletion of oligodendrocyte progenitors does not occur following repeated episodes of focal demyelination in the rat central nervous system

21 January 2018

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Remyelination occurs as extensively but more slowly in old rats compared to young rats following gliotoxin-induced CNS demyelination

21 January 2018

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Enhanced number and activity of mitochondria in multiple sclerosis lesions

21 January 2018

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Identification and investigation of mitochondria lacking cytochrome c oxidase activity in axons

21 January 2018

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Mitochondrial Protein Nitration Primes Neurodegeneration in Experimental Autoimmune Encephalomyelitis

21 January 2018

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Neuropathology of white matter disease in Leber's hereditary optic neuropathy

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Remyelination in multiple sclerosis

26 November 2018

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12 December 2020

Multiple sclerosis: remyelination in acute lesions

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12 December 2020

The regulation of bidirectional mitochondrial transport is coordinated with axonal outgrowth

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Conduction in segmentally demyelinated mammalian central axons

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Focal accumulation of intra-axonal mitochondria in demyelination of the cat optic nerve

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Mitochondrial dysfunction plays a key role in progressive axonal loss in Multiple Sclerosis

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Ions, energy and axonal injury: towards a molecular neurology of multiple sclerosis

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The restoration of conduction by central remyelination

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Identifiers

DOI

10.1093/BRAIN/AWR110

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21705418%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21705418%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

PubMed publication ID

21705418

1 reference