A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms (Q30513464)

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12 February 2020

title

A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms (English)

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12 February 2020

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4

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12 February 2020

Natalia Trayanova

10

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12 February 2020

Crystal M Ripplinger

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author name string

Jonathan D Moreno

1

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12 February 2020

Z Iris Zhu

2

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12 February 2020

Pei-Chi Yang

3

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12 February 2020

Mao-Tsuen Jeng

5

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12 February 2020

Chaoyi Kang

6

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12 February 2020

Lianguo Wang

7

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12 February 2020

Jason D Bayer

8

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12 February 2020

David J Christini

9

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12 February 2020

Robert S Kass

12

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12 February 2020

Colleen E Clancy

13

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12 February 2020

language of work or name

English

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publication date

1 August 2011

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Science Translational Medicine

12 February 2020

published in

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12 February 2020

volume

3

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12 February 2020

issue

98

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12 February 2020

page(s)

98ra83

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Transmural heterogeneity and remodeling of ventricular excitation-contraction coupling in human heart failure

12 February 2020

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New developments in atrial antiarrhythmic drug therapy

28 July 2018

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Specificities of atrial electrophysiology: Clues to a better understanding of cardiac function and the mechanisms of arrhythmias

28 July 2018

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Multiscale modelling of drug-induced effects on cardiac electrophysiological activity

28 July 2018

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Is heart size a factor in ventricular fibrillation? Or how close are rabbit and human hearts?

28 July 2018

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Flecainide sensitivity of a Na channel long QT mutation shows an open-channel blocking mechanism for use-dependent block

28 July 2018

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State-dependent trapping of flecainide in the cardiac sodium channel

28 July 2018

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28 July 2018

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Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues

28 July 2018

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Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations

28 July 2018

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The rise of computational biology

28 July 2018

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Preferential block of late sodium current in the LQT3 DeltaKPQ mutant by the class I(C) antiarrhythmic flecainide.

28 July 2018

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Slow conduction in cardiac tissue, I: effects of a reduction of excitability versus a reduction of electrical coupling on microconduction.

28 July 2018

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Local anesthetics as effectors of allosteric gating. Lidocaine effects on inactivation-deficient rat skeletal muscle Na channels

28 July 2018

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Vulnerability in an excitable medium: analytical and numerical studies of initiating unidirectional propagation

28 July 2018

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Mechanism of flecainide's rate-dependent actions on action potential duration in canine atrial tissue

28 July 2018

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On the molecular nature of the lidocaine receptor of cardiac Na+ channels. Modification of block by alterations in the alpha-subunit III-IV interdomain

28 July 2018

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Antiarrhythmic agents: the modulated receptor mechanism of action of sodium and calcium channel-blocking drugs

28 July 2018

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Effect of Flecainide on Action Potentials and Alternating Current-Induced Arrhythmias in Mammalian Myocardium

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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12 December 2020

K+ channel blocking actions of flecainide compared with those of propafenone and quinidine in adult rat ventricular myocytes

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12 December 2020

Comparison of the effects of class I anti-arrhythmic drugs, cibenzoline, mexiletine and flecainide, on the delayed rectifier K+ current of guinea-pig ventricular myocytes

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

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12 December 2020

Differential block of cardiac delayed rectifier current by class Ic antiarrhythmic drugs: evidence for open channel block and unblock

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12 December 2020

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Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21885405%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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12 February 2020

PubMed publication ID

21885405

1 reference