INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells (Q30525001)

19 October 2017

INF2 promotes the formation of detyrosinated microtubules necessary for centrosome reorientation in T cells (English)

1 reference

19 October 2017

Laura Andrés-Delgado

1

1 reference

19 October 2017

Olga M Antón

2

1 reference

19 October 2017

Francesca Bartolini

3

1 reference

19 October 2017

Ana Ruiz-Sáenz

4

1 reference

19 October 2017

Isabel Correas

5

1 reference

19 October 2017

Gregg G Gundersen

6

1 reference

19 October 2017

Miguel A Alonso

7

1 reference

19 October 2017

language of work or name

English

0 references

publication date

1 September 2012

1 reference

19 October 2017

Journal of Cell Biology

1 reference

19 October 2017

198

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19 October 2017

6

1 reference

19 October 2017

1025-1037

1 reference

describes a project that uses

19 October 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3444772/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Casein kinase I delta controls centrosome positioning during T cell activation

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Splice variant-specific cellular function of the formin INF2 in maintenance of Golgi architecture

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Centrosome docking at the immunological synapse is controlled by Lck signaling

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Rho activation of mDia formins is modulated by an interaction with inverted formin 2 (INF2)

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Par3 and dynein associate to regulate local microtubule dynamics and centrosome orientation during migration

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Beyond polymer polarity: how the cytoskeleton builds a polarized cell

20 June 2018

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MTOC translocation modulates IS formation and controls sustained T cell signaling

20 June 2018

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The formin mDia2 stabilizes microtubules independently of its actin nucleation activity

20 June 2018

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Differential trafficking of Kif5c on tyrosinated and detyrosinated microtubules in live cells

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Microtubule stabilization specifies initial neuronal polarization

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20 June 2018

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Formins regulate the actin-related protein 2/3 complex-independent polarization of the centrosome to the immunological synapse

20 June 2018

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Regulation of T-cell activation by the cytoskeleton

20 June 2018

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Recruitment of dynein to the Jurkat immunological synapse

20 June 2018

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Tubulin tyrosination is a major factor affecting the recruitment of CAP-Gly proteins at microtubule plus ends.

20 June 2018

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INF2 Is a WASP homology 2 motif-containing formin that severs actin filaments and accelerates both polymerization and depolymerization.

20 June 2018

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20 June 2018

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Nuclear movement regulated by Cdc42, MRCK, myosin, and actin flow establishes MTOC polarization in migrating cells

20 June 2018

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EB1 and APC bind to mDia to stabilize microtubules downstream of Rho and promote cell migration

20 June 2018

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HDAC6 deacetylase activity links the tubulin cytoskeleton with immune synapse organization

20 June 2018

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Crystal structures of a Formin Homology-2 domain reveal a tethered dimer architecture

20 June 2018

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20 June 2018

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20 June 2018

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Recruitment of Nck by CD3 epsilon reveals a ligand-induced conformational change essential for T cell receptor signaling and synapse formation

20 June 2018

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Export from pericentriolar endocytic recycling compartment to cell surface depends on stable, detyrosinated (glu) microtubules and kinesin.

20 June 2018

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Cdc42, dynein, and dynactin regulate MTOC reorientation independent of Rho-regulated microtubule stabilization

20 June 2018

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mDia mediates Rho-regulated formation and orientation of stable microtubules

20 June 2018

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Differential clustering of CD4 and CD3zeta during T cell recognition

20 June 2018

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FRL, a novel formin-related protein, binds to Rac and regulates cell motility and survival of macrophages

20 June 2018

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Detyrosination of tubulin regulates the interaction of intermediate filaments with microtubules in vivo via a kinesin-dependent mechanism

20 June 2018

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TCR, LFA-1, and CD28 play unique and complementary roles in signaling T cell cytoskeletal reorganization.

20 June 2018

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Rho guanosine triphosphatase mediates the selective stabilization of microtubules induced by lysophosphatidic acid

20 June 2018

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Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism

20 June 2018

1 reference

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Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors

20 June 2018

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p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin

20 June 2018

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Effects of taxol and taxol/hyperthermia treatments on the functional polarization of cytotoxic T lymphocytes.

20 June 2018

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Regulation of the polarization of T cells toward antigen-presenting cells by Ras-related GTPase CDC42

20 June 2018

1 reference

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Selective stabilization of microtubules oriented toward the direction of cell migration

20 June 2018

1 reference

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Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules

20 June 2018

1 reference

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Formin INF2 regulates MAL-mediated transport of Lck to the plasma membrane of human T lymphocytes

20 June 2018

1 reference

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Distinct roles for the actin nucleators Arp2/3 and hDia1 during NK-mediated cytotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Substoichiometric binding of taxol suppresses microtubule dynamics.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Tubulin tyrosination navigates the kinesin-1 motor domain to axons

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Dynamic polarization of the microtubule cytoskeleton during CTL-mediated killing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

The formin INF2 regulates basolateral-to-apical transcytosis and lumen formation in association with Cdc42 and MAL2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Centrosome polarization delivers secretory granules to the immunological synapse.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Tyrosine phosphorylation of α tubulin in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.201202137

Reorientation of the microtubule-organizing center and the Golgi apparatus in cloned cytotoxic lymphocytes triggered by binding to lysable target cells

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3444772

26 November 2018

Identifiers

DOI

10.1083/JCB.201202137

1 reference

19 October 2017

1 reference

19 October 2017

PubMed publication ID

22986496

1 reference