Mechanism for Hypocretin-mediated sleep-to-wake transitions (Q30525530)

13 August 2017

Mechanism for Hypocretin-mediated sleep-to-wake transitions (English)

1 reference

13 August 2017

0 references

Matthew E Carter

1

1 reference

13 August 2017

Julia Brill

2

1 reference

13 August 2017

Patricia Bonnavion

3

1 reference

13 August 2017

John R Huguenard

4

1 reference

13 August 2017

Ramon Huerta

5

1 reference

13 August 2017

Luis de Lecea

6

1 reference

13 August 2017

language of work or name

English

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publication date

5 September 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

1 reference

13 August 2017

109

1 reference

13 August 2017

39

1 reference

13 August 2017

E2635-44

1 reference

Optogenetics in neural systems

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Effects and mechanisms of wakefulness on local cortical networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Knockdown of orexin type 1 receptor in rat locus coeruleus increases REM sleep during the dark period

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Tuning arousal with optogenetic modulation of locus coeruleus neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Synchrony with shunting inhibition in a feedforward inhibitory network.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

POTENTIAL, IMPEDANCE, AND RECTIFICATION IN MEMBRANES

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Sleep homeostasis modulates hypocretin-mediated sleep-to-wake transitions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Robust microcircuit synchronization by inhibitory connections

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Bi-stable neural state switches

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Role of orexin input in the diurnal rhythm of locus coeruleus impulse activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Neural substrates of awakening probed with optogenetic control of hypocretin neurons

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The neural circuit of orexin (hypocretin): maintaining sleep and wakefulness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Hypothalamic regulation of sleep and circadian rhythms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Organization of hypocretin/orexin efferents to locus coeruleus and basal forebrain arousal-related structures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The neurobiology of sleep: genetics, cellular physiology and subcortical networks

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The hypocretins: setting the arousal threshold

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

SB-334867-A: the first selective orexin-1 receptor antagonist

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Neurons containing hypocretin (orexin) project to multiple neuronal systems

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The hypocretins: hypothalamus-specific peptides with neuroexcitatory activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Activity of norepinephrine-containing locus coeruleus neurons in behaving rats anticipates fluctuations in the sleep-waking cycle.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Behavioral activation of rats during intraventricular infusion of norepinephrine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Evidence that locus coeruleus is the site where clonidine and drugs acting at alpha 1- and alpha 2-adrenoceptors affect sleep and arousal mechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Neuronal excitability modulation over the sleep cycle: a structural and mathematical model

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Sleep cycle oscillation: reciprocal discharge by two brainstem neuronal groups.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Discharge of identified orexin/hypocretin neurons across the sleep-waking cycle.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Hypocretin (orexin) deficiency in human narcolepsy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

The locus coeruleus–noradrenergic system: modulation of behavioral state and state-dependent cognitive processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Transgenic expression of Cre recombinase from the tyrosine hydroxylase locus

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Photocycles of channelrhodopsin-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Orexins cause depolarization via nonselective cationic and K+ channels in isolated locus coeruleus neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

A mathematical model of homeostatic regulation of sleep-wake cycles by hypocretin/orexin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Orexin directly excites orexin neurons through orexin 2 receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1202526109

Behavioral correlates of activity in identified hypocretin/orexin neurons

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

The wake-promoting hypocretin-orexin neurons are in an intrinsic state of membrane depolarization.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

SB-334867-A antagonises orexin mediated excitation in the locus coeruleus

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Hypocretin-1 modulates rapid eye movement sleep through activation of locus coeruleus neurons.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Hypocretin (orexin) activation and synaptic innervation of the locus coeruleus noradrenergic system.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Cellular and network models for intrathalamic augmenting responses during 10-Hz stimulation

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3465396

Synergistic sedative effects of noradrenergic alpha(1)- and beta-receptor blockade on forebrain electroencephalographic and behavioral indices

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22955882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A central pattern generator to control a pyloric-based system

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22955882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Interaction between the corticotropin-releasing factor system and hypocretins (orexins): a novel circuit mediating stress response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22955882

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1202526109

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference