The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury (Q30536373)

10 October 2017

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury (English)

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10 October 2017

8

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10 October 2017

Patrick N Harter

12

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Rudi Beschorner

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Rudi Beschorner

11

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Britta Engelhardt

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Britta Engelhardt

14

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Michel Mittelbronn

13

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Michel Mittelbronn

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10 October 2017

10

Marco Prinz

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10 October 2017

9

Matthias Endres

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10 October 2017

Gaby Enzmann

1

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10 October 2017

Caroline Mysiorek

2

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10 October 2017

Roser Gorina

3

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10 October 2017

Yu-Jung Cheng

4

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10 October 2017

Sharang Ghavampour

5

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10 October 2017

Melanie-Jane Hannocks

6

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10 October 2017

Vincent Prinz

7

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10 October 2017

Lydia Sorokin

15

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10 October 2017

27 December 2012

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10 October 2017

Acta Neuropathologica

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10 October 2017

125

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10 October 2017

395-412

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10 October 2017

3

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Creative Commons Attribution 2.0 Generic

10 October 2017

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27 December 2012

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April 2022 Public Data File from Crossref

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ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3578720/fullTextXML

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https://scigraph.springernature.com/pub.10.1007/s00401-012-1076-3

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cites work

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The endothelial glycocalyx as a barrier to leukocyte adhesion and its mediation by extracellular proteases

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Shedding of the endothelial glycocalyx in arterioles, capillaries, and venules and its effect on capillary hemodynamics during inflammation

20 June 2018

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Acute anti-inflammatory approaches to ischemic stroke

20 June 2018

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Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

20 June 2018

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Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

20 June 2018

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Effects of G-CSF treatment on neutrophil mobilization and neurological outcome after transient focal ischemia.

20 June 2018

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The blood-brain and the blood-cerebrospinal fluid barriers: function and dysfunction.

20 June 2018

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Update of the stroke therapy academic industry roundtable preclinical recommendations

20 June 2018

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Perivascular spaces and the two steps to neuroinflammation

20 June 2018

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Tracking the inflammatory response in stroke in vivo by sensing the enzyme myeloperoxidase

20 June 2018

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Inflammation and the neurovascular unit in the setting of focal cerebral ischemia

20 June 2018

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Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA.

20 June 2018

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Genetic influence on immune phenotype revealed strain-specific variations in peripheral blood lineages

20 June 2018

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Getting to the site of inflammation: the leukocyte adhesion cascade updated

20 June 2018

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Three-dimensional cerebral vasculature of the CBA mouse brain: a magnetic resonance imaging and micro computed tomography study

20 June 2018

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Vasculoprotective properties of the endothelial glycocalyx: effects of fluid shear stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Effect of neutrophil depletion on gelatinase expression, edema formation and hemorrhagic transformation after focal ischemic stroke

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

20 June 2018

1 reference

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Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Neuroprotective effect of granulocyte colony-stimulating factor after focal cerebral ischemia.

20 June 2018

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Anti-leukocyte antibodies: LeukArrest (Hu23F2G) and Enlimomab (R6.5) in acute stroke.

20 June 2018

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The role of leukocytes following cerebral ischemia: pathogenic variable or bystander reaction to emerging infarct?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Examination of several potential mechanisms for the negative outcome in a clinical stroke trial of enlimomab, a murine anti-human intercellular adhesion molecule-1 antibody: a bedside-to-bench study

20 June 2018

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Use of anti-ICAM-1 therapy in ischemic stroke: results of the Enlimomab Acute Stroke Trial

20 June 2018

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Pathobiology of ischaemic stroke: an integrated view

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

CD18-mediated neutrophil recruitment contributes to the pathogenesis of reperfused but not nonreperfused stroke

20 June 2018

1 reference

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Neuroprotective effects of gelsolin during murine stroke

20 June 2018

1 reference

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Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

The development of experimental autoimmune encephalomyelitis in the mouse requires alpha4-integrin but not alpha4beta7-integrin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Morphological characteristics and distribution pattern of the arterial vessels in human cerebral cortex: a scanning electron microscope study

20 June 2018

1 reference

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Adhesion molecule phenotype of T lymphocytes in inflamed CNS.

20 June 2018

1 reference

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Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Exacerbation of cerebral injury in mice that express the P-selectin gene: identification of P-selectin blockade as a new target for the treatment of stroke

20 June 2018

1 reference

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Brain endothelium lack one of two pathways of P-selectin-mediated neutrophil adhesion.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Progressive expression of immunomolecules on activated microglia and invading leukocytes following focal cerebral ischemia in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Cerebral protection in homozygous null ICAM-1 mice after middle cerebral artery occlusion. Role of neutrophil adhesion in the pathogenesis of stroke

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Selective expression of Ly-6G on myeloid lineage cells in mouse bone marrow. RB6-8C5 mAb to granulocyte-differentiation antigen (Gr-1) detects members of the Ly-6 family

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Lymphocytes infiltrating the CNS during inflammation display a distinctive phenotype and bind to VCAM-1 but not to MAdCAM-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

P-selectin and intercellular adhesion molecule-1 expression after focal brain ischemia and reperfusion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Cerebral infarction. Evolution of histopathological changes after occlusion of a middle cerebral artery in primates.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

The cranial arachnoid and pia mater in man: anatomical and ultrastructural observations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Interrelationships of the pia mater and the perivascular (Virchow-Robin) spaces in the human cerebrum

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Homing to central nervous system vasculature by antigen-specific lymphocytes. II. Lymphocyte/endothelial cell adhesion during the initial stages of autoimmune demyelination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Intracerebral injection of proinflammatory cytokines or leukocyte chemotaxins induces minimal myelomonocytic cell recruitment to the parenchyma of the central nervous system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Reperfusion increases neutrophils and leukotriene B4 receptor binding in rat focal ischemia.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Dynamics of polymorphonuclear leukocyte accumulation in acute cerebral infarction and their correlation with brain tissue damage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Polymorphonuclear neutrophils contribute to infarction and oxidative stress in the cortex but not in the striatum after ischemia–reperfusion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Granulocyte-colony stimulating factor delays PWI/DWI mismatch evolution and reduces final infarct volume in permanent-suture and embolic focal cerebral ischemia models in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Positron emission tomography imaging of poststroke angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Attenuation of delayed neuronal death after mild focal ischemia in mice by inhibition of the caspase family.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Neuroprotection with the CXCL8 inhibitor repertaxin in transient brain ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Hierarchical microimaging for multiscale analysis of large vascular networks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

CD40/CD40 ligand signaling in mouse cerebral microvasculature after focal ischemia/reperfusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Deficiency of intercellular adhesion molecule 1 attenuates microcirculatory disturbance and infarction size in focal cerebral ischemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN): an adaptive dose-response study of UK-279,276 in acute ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Endothelial ICAM-1 expression associated with inflammatory cell response in human ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Differences in the cerebrovascular anatomy of C57black/6 and SV129 mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Optimal depth and duration of mild hypothermia in a focal model of transient cerebral ischemia: effects on neurologic outcome, infarct size, apoptosis, and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Systemic inflammatory stimulus potentiates the acute phase and CXC chemokine responses to experimental stroke and exacerbates brain damage via interleukin-1- and neutrophil-dependent mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Effect of Intravenous Thrombolysis on MRI Parameters and Functional Outcome in Acute Stroke <6 Hours

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

AXIS: a trial of intravenous granulocyte colony-stimulating factor in acute ischemic stroke

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood-brain barrier endothelium.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Metalloproteinases control brain inflammation induced by pertussis toxin in mice overexpressing the chemokine CCL2 in the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Leukocyte infiltration in acute hemispheric ischemic stroke.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Endothelial basement membrane laminin alpha5 selectively inhibits T lymphocyte extravasation into the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Selective neuronal vulnerability following mild focal brain ischemia in the mouse.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

The tight junctions of the leptomeningeal blood-cerebrospinal fluid barrier during development.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3578720

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

26 November 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00401-012-1076-3

Immunochemical and autoantigenic properties of the globular domain of basement membrane collagen (type IV)

21 January 2018

1 reference

12 December 2020

Role of cell adhesion molecules in brain injury after transient middle cerebral artery occlusion in the rat

1 reference

12 December 2020

Lack of evidence for neutrophil participation during infarct formation following focal cerebral ischemia in the rat

1 reference

12 December 2020

T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cells

1 reference

12 December 2020

Contributions of LFA-1 and Mac-1 to brain injury and microvascular dysfunction induced by transient middle cerebral artery occlusion

1 reference

12 December 2020

The Desmoteplase in Acute Ischemic Stroke Trial (DIAS)

1 reference

12 December 2020

E- and P-selectin are not required for the development of experimental autoimmune encephalomyelitis in C57BL/6 and SJL mice

1 reference

12 December 2020

Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice

1 reference

12 December 2020

Myeloperoxidase attracts neutrophils by physical forces

1 reference

12 December 2020

Cerebrospinal Fluid Cytology After Stroke

1 reference

12 December 2020

10.1007/S00401-012-1076-3

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DOI

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Dimensions Publication ID

10 October 2017

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1 reference

10 October 2017

1 reference