Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes (Q30536567)

15 August 2017

Exogenous delivery of chaperonin subunit fragment ApiCCT1 modulates mutant Huntingtin cellular phenotypes (English)

1 reference

15 August 2017

7

1 reference

23 June 2017

8

Judith Frydman

1 reference

15 August 2017

6

Charles G Glabe

1 reference

15 August 2017

Emily M Sontag

1

1 reference

15 August 2017

Lukasz A Joachimiak

2

1 reference

15 August 2017

Zhiqun Tan

3

1 reference

15 August 2017

Anthony Tomlinson

4

1 reference

15 August 2017

David E Housman

5

1 reference

15 August 2017

Leslie M Thompson

9

1 reference

15 August 2017

language of work or name

English

0 references

publication date

30 January 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

15 August 2017

1 reference

15 August 2017

110

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15 August 2017

3077-3082

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15 August 2017

8

1 reference

describes a project that uses

15 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3581981/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Detection of Mutant Huntingtin Aggregation Conformers and Modulation of SDS-Soluble Fibrillar Oligomers by Small Molecules

1 reference

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Methylene blue modulates huntingtin aggregation intermediates and is protective in Huntington's disease models

20 June 2018

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Cell-penetrating peptides: breaking through to the other side

20 June 2018

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Cellular strategies of protein quality control

20 June 2018

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Methods for measuring proteasome activity: current limitations and future developments

20 June 2018

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Chaperone networks: tipping the balance in protein folding diseases

20 June 2018

1 reference

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Mutant huntingtin fragments form oligomers in a polyglutamine length-dependent manner in vitro and in vivo

20 June 2018

1 reference

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The chaperonin TRiC blocks a huntingtin sequence element that promotes the conformational switch to aggregation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581981

Loss of Hsp70 exacerbates pathogenesis but not levels of fibrillar aggregates in a mouse model of Huntington's disease

20 June 2018

1 reference

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CEP-1347 reduces mutant huntingtin-associated neurotoxicity and restores BDNF levels in R6/2 mice

20 June 2018

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Adapting proteostasis for disease intervention

20 June 2018

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The chaperonin TRiC controls polyglutamine aggregation and toxicity through subunit-specific interactions

20 June 2018

1 reference

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Shuttling mechanism of peroxisome targeting signal type 1 receptor Pex5: ATP-independent import and ATP-dependent export

20 June 2018

1 reference

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Contribution of nuclear and extranuclear polyQ to neurological phenotypes in mouse models of Huntington's disease

20 June 2018

1 reference

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Modulation of neurodegeneration by molecular chaperones

20 June 2018

1 reference

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Mechanism of the eukaryotic chaperonin: protein folding in the chamber of secrets.

20 June 2018

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Inclusion body formation reduces levels of mutant huntingtin and the risk of neuronal death

20 June 2018

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20 June 2018

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A cell-based assay for aggregation inhibitors as therapeutics of polyglutamine-repeat disease and validation in Drosophila

20 June 2018

1 reference

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Hsp70 and hsp40 chaperones can inhibit self-assembly of polyglutamine proteins into amyloid-like fibrils

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581981

Cell-penetrating peptides.

20 June 2018

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Aggregation of huntingtin in neuronal intranuclear inclusions and dystrophic neurites in brain

20 June 2018

1 reference

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Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation

20 June 2018

1 reference

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Cell internalization of the third helix of the Antennapedia homeodomain is receptor-independent.

20 June 2018

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Protein folding in the central cavity of the GroEL-GroES chaperonin complex

20 June 2018

1 reference

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A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581981

Suppression of polyglutamine-mediated neurodegeneration in Drosophila by the molecular chaperone HSP70.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222663110

Over-expression of inducible HSP70 chaperone suppresses neuropathology and improves motor function in SCA1 mice

21 January 2018

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Aggregated polyglutamine peptides delivered to nuclei are toxic to mammalian cells

21 January 2018

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Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.

21 January 2018

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Cytosolic chaperonin prevents polyglutamine toxicity with altering the aggregation state.

21 January 2018

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Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.1222663110

Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells

21 January 2018

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Metagrowth: a new resource for the building of metabolic hypotheses in microbiology

21 January 2018

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PARK7 DJ-1 protects against degeneration of nigral dopaminergic neurons in Parkinson's disease rat model.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222663110

DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222663110

Huntingtin-encoded polyglutamine expansions form amyloid-like protein aggregates in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1222663110

21 January 2018

Isolation of nucleoli

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581981

Sensitive biochemical aggregate detection reveals aggregation onset before symptom development in cellular and murine models of Huntington's disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3581981

26 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/23365139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A Truncated HIV-1 Tat Protein Basic Domain Rapidly Translocates through the Plasma Membrane and Accumulates in the Cell Nucleus

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23365139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1222663110

1 reference

15 August 2017

0 references

1 reference

15 August 2017

1 reference