Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition (Q30536707)

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English	Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition	scientific article

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19 February 2020

Insulin inhibits cardiac mesoderm, not mesendoderm, formation during cardiac differentiation of human pluripotent stem cells and modulation of canonical Wnt signaling can rescue this inhibition (English)

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19 February 2020

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19 February 2020

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19 February 2020

Timothy J. Kamp

4

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19 February 2020

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Jianhua Zhang

2

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19 February 2020

Sean P Palecek

5

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19 February 2020

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1 March 2013

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19 February 2020

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19 February 2020

31

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19 February 2020

3

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19 February 2020

447-457

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19 February 2020

A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development

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28 July 2018

Simultaneous voltage and calcium mapping of genetically purified human induced pluripotent stem cell-derived cardiac myocyte monolayers

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28 July 2018

Eomesodermin induces Mesp1 expression and cardiac differentiation from embryonic stem cells in the absence of Activin

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28 July 2018

Generation of human vascular smooth muscle subtypes provides insight into embryological origin-dependent disease susceptibility

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28 July 2018

Modulation of Wnt/β-catenin signaling in human embryonic stem cells using a 3-D microwell array.

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28 July 2018

Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size

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28 July 2018

The T-box transcription factor Eomesodermin acts upstream of Mesp1 to specify cardiac mesoderm during mouse gastrulation

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28 July 2018

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

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28 July 2018

Chemically defined conditions for human iPSC derivation and culture

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28 July 2018

IGF signaling directs ventricular cardiomyocyte proliferation during embryonic heart development

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28 July 2018

Stage-specific optimization of activin/nodal and BMP signaling promotes cardiac differentiation of mouse and human pluripotent stem cell lines

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28 July 2018

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

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28 July 2018

Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells

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28 July 2018

Insulin stabilizes microvascular endothelial barrier function via phosphatidylinositol 3-kinase/Akt-mediated Rac1 activation.

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28 July 2018

Expansion and maintenance of human embryonic stem cell-derived endothelial cells by TGFbeta inhibition is Id1 dependent

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28 July 2018

Modeling early retinal development with human embryonic and induced pluripotent stem cells

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28 July 2018

Human ISL1 heart progenitors generate diverse multipotent cardiovascular cell lineages

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28 July 2018

Human induced pluripotent stem cells free of vector and transgene sequences

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28 July 2018

Hematopoietic and endothelial differentiation of human induced pluripotent stem cells

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28 July 2018

Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancer

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28 July 2018

Chemically defined medium supporting cardiomyocyte differentiation of human embryonic stem cells

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28 July 2018

IGFBP-4 is an inhibitor of canonical Wnt signalling required for cardiogenesis

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28 July 2018

Human cardiovascular progenitor cells develop from a KDR+ embryonic-stem-cell-derived population

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28 July 2018

Rac1 activation controls nuclear localization of beta-catenin during canonical Wnt signaling.

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28 July 2018

The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway

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28 July 2018

Insulin redirects differentiation from cardiogenic mesoderm and endoderm to neuroectoderm in differentiating human embryonic stem cells

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28 July 2018

Induced pluripotent stem cell lines derived from human somatic cells

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28 July 2018

Enhanced cardiomyogenesis of human embryonic stem cells by a small molecular inhibitor of p38 MAPK.

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28 July 2018

Self-renewal of human embryonic stem cells requires insulin-like growth factor-1 receptor and ERBB2 receptor signaling

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28 July 2018

Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts

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28 July 2018

IGF and FGF cooperatively establish the regulatory stem cell niche of pluripotent human cells in vitro.

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28 July 2018

Proliferation of cardiomyocytes derived from human embryonic stem cells is mediated via the IGF/PI 3-kinase/Akt signaling pathway

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28 July 2018

Embryonic stem cell differentiation: emergence of a new era in biology and medicine

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28 July 2018

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28 July 2018

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28 July 2018

Endothelial cells derived from human embryonic stem cells

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28 July 2018

GATA4 transcription factor is required for ventral morphogenesis and heart tube formation

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28 July 2018

Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B

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28 July 2018

Phosphatidylinositol 3-kinase-Akt pathway plays a critical role in early cardiomyogenesis by regulating canonical Wnt signaling

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21 January 2018

Robust cardiomyocyte differentiation from human pluripotent stem cells via temporal modulation of canonical Wnt signaling.

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Embryonic stem cell lines derived from human blastocysts

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Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

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21 January 2018

Chamber-specific cardiac expression of Tbx5 and heart defects in Holt-Oram syndrome

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NKX2-5(eGFP/w) hESCs for isolation of human cardiac progenitors and cardiomyocytes.

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Early cell fate decisions of human embryonic stem cells and mouse epiblast stem cells are controlled by the same signalling pathways

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21 January 2018

Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method

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21 January 2018

Activin a efficiently specifies definitive endoderm from human embryonic stem cells only when phosphatidylinositol 3-kinase signaling is suppressed.

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Endothelial cells derived from human embryonic stem cells form durable blood vessels in vivo.

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21 January 2018

A highly efficient method to differentiate smooth muscle cells from human embryonic stem cells

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21 January 2018

MesP1 and MesP2 are essential for the development of cardiac mesoderm

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26 November 2018

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis

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Wnt3a-induced mesoderm formation and cardiomyogenesis in human embryonic stem cells

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12 December 2020

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10.1002/STEM.1289

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19 February 2020

PMC publication ID

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Europe PubMed Central

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19 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23193013%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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