Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II. (Q30540902)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

title

Metformin impairs glucose consumption and survival in Calu-1 cells by direct inhibition of hexokinase-II (English)

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3 March 2020

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2

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Silvia Ravera

4

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3 March 2020

Michela Massollo

5

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3 March 2020

Adriana Amaro

7

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3 March 2020

Mario Passalacqua

8

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3 March 2020

Ulrich Pfeffer

10

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3 March 2020

Renzo Cordera

11

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3 March 2020

Davide Maggi

12

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3 March 2020

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Gianmario Sambuceti

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3 March 2020

author name string

Barbara Salani

1

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3 March 2020

Alberto Del Rio

3

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3 March 2020

Anna Maria Orengo

6

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3 March 2020

Sara Maffioli

9

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language of work or name

English

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publication date

1 January 2013

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3 March 2020

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3 March 2020

volume

3

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3 March 2020

page(s)

2070

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

3 March 2020

copyright license

start time

25 June 2013

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3691576/fullTextXML

inferred from PubMed Central ID database lookup

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Metformin abolishes increased tumor (18)F-2-fluoro-2-deoxy-D-glucose uptake associated with a high energy diet

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Subcellular localization of hexokinases I and II directs the metabolic fate of glucose

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Hexokinase-2 bound to mitochondria: cancer's stygian link to the "Warburg Effect" and a pivotal target for effective therapy

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Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression

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Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

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Identifiers

DOI

10.1038/SREP02070

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

3 March 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json

3 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23797762%20AND%20SRC:MED&resulttype=core&format=json