Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice (Q30558348)

19 August 2017

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice (English)

1 reference

19 August 2017

0 references

1 reference

Michihiro Mieda

1

1 reference

19 August 2017

Jon T Willie

2

1 reference

19 August 2017

Junko Hara

3

1 reference

19 August 2017

Christopher M Sinton

4

1 reference

19 August 2017

Takeshi Sakurai

5

1 reference

19 August 2017

Masashi Yanagisawa

6

1 reference

19 August 2017

language of work or name

English

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publication date

16 March 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

19 August 2017

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19 August 2017

101

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19 August 2017

4649-4654

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19 August 2017

13

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Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

The neurobiology, diagnosis, and treatment of narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Sleeping with the hypothalamus: emerging therapeutic targets for sleep disorders

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

The role of cerebrospinal fluid hypocretin measurement in the diagnosis of narcolepsy and other hypersomnias

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Orexins/hypocretins in the ob/ob mouse: hypothalamic gene expression, peptide content and metabolic effects

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Arousal effect of orexin A depends on activation of the histaminergic system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

To eat or to sleep? Orexin in the regulation of feeding and wakefulness

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Reduced number of hypocretin neurons in human narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Narcolepsy: a neurodegenerative disease of the hypocretin system?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

The novel brain neuropeptide, orexin-A, modulates the sleep-wake cycle of rats

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Orexin A activates locus coeruleus cell firing and increases arousal in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Distribution of orexin neurons in the adult rat brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Neurons containing hypocretin (orexin) project to multiple neuronal systems

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Modafinil induces wakefulness without intensifying motor activity or subsequent rebound hypersomnolence in the rat.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Pharmacological aspects of human and canine narcolepsy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Efficient selection for high-expression transfectants with a novel eukaryotic vector

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Neuroendocrine and electroencephalographic sleep changes due to acute amphetamine ingestion in human beings

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Strain differences in amphetamine sensitivity in mice. II. Overcompensation of paradoxical sleep after deprivation in two C57 strains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Hypocretin (orexin) deficiency in human narcolepsy.

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400590101

Genetic ablation of orexin neurons in mice results in narcolepsy, hypophagia, and obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400590101

Circadian-dependent and circadian-independent behavioral actions of hypocretin/orexin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400590101

Decreased brain histamine content in hypocretin/orexin receptor-2 mutated narcoleptic dogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400590101

Effects of orexin-A on memory processing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0400590101

Hypocretin increases impulse flow in the septohippocampal GABAergic pathway: implications for arousal via a mechanism of hippocampal disinhibition.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Systemic administration of hypocretin-1 reduces cataplexy and normalizes sleep and waking durations in narcoleptic dogs

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=384801

Independent feeding and metabolic actions of orexins in mice

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15070772

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effects of single and chronic intracerebroventricular administration of the orexins on feeding in the rat

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15070772

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0400590101

1 reference

19 August 2017

0 references

1 reference

19 August 2017

1 reference