Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction (Q30559284)

20 August 2017

Histone deacetylase 6-mediated selective autophagy regulates COPD-associated cilia dysfunction (English)

1 reference

20 August 2017

0 references

18

John Quackenbush

0 references

Bin Shan

Bin Shan

12

0 references

Yohannes Tesfaigzi

Yohannes Tesfaigzi

16

0 references

Chang Hyeok An

Chang Hyeok An

11

0 references

Suzanne M Cloonan

Suzanne M Cloonan

2

0 references

Edwin K Silverman

19

Edwin K Silverman

1 reference

20 August 2017

10

Kenji Mizumura

1 reference

20 August 2017

25

Augustine M K Choi

1 reference

20 August 2017

24

Stefan W Ryter

1 reference

20 August 2017

Hilaire C Lam

1

1 reference

20 August 2017

Abhiram R Bhashyam

3

1 reference

20 August 2017

Jeffery A Haspel

4

1 reference

20 August 2017

Anju Singh

5

1 reference

20 August 2017

J Fah Sathirapongsasuti

6

1 reference

20 August 2017

Morgan Cervo

7

1 reference

20 August 2017

Hongwei Yao

8

1 reference

20 August 2017

Anna L Chung

9

1 reference

20 August 2017

Jonathan M Franks

13

1 reference

20 August 2017

Kathleen J Haley

14

1 reference

20 August 2017

Caroline A Owen

15

1 reference

20 August 2017

George R Washko

17

1 reference

20 August 2017

Irfan Rahman

20

1 reference

20 August 2017

Hong Pyo Kim

21

1 reference

20 August 2017

Ashfaq Mahmood

22

1 reference

20 August 2017

Shyam S Biswal

23

1 reference

20 August 2017

language of work or name

English

0 references

publication date

8 November 2013

1 reference

Journal of Clinical Investigation

20 August 2017

1 reference

20 August 2017

123

1 reference

20 August 2017

12

1 reference

20 August 2017

5212-5230

1 reference

describes a project that uses

20 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3859407/fullTextXML

inferred from PubMed Central ID database lookup

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20 June 2018

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20 June 2018

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Target-of-rapamycin complex 1 (Torc1) signaling modulates cilia size and function through protein synthesis regulation

20 June 2018

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20 June 2018

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Protein Aggregates Are Recruited to Aggresome by Histone Deacetylase 6 via Unanchored Ubiquitin C Termini

20 June 2018

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Cigarette smoke exposure induces CFTR internalization and insolubility, leading to airway surface liquid dehydration

20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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20 June 2018

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Acetylation-deacetylation of the transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2) regulates its transcriptional activity and nucleocytoplasmic localization

20 June 2018

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20 June 2018

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Autophagy protein microtubule-associated protein 1 light chain-3B (LC3B) activates extrinsic apoptosis during cigarette smoke-induced emphysema

20 June 2018

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20 June 2018

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20 June 2018

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Generalizing moving averages for tiling arrays using combined p-value statistics.

20 June 2018

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The antioxidant transcription factor Nrf2 negatively regulates autophagy and growth arrest induced by the anticancer redox agent mitoquinone

20 June 2018

1 reference

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Cigarette smoke-induced autophagy is regulated by SIRT1-PARP-1-dependent mechanism: implication in pathogenesis of COPD.

20 June 2018

1 reference

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20 June 2018

The Beclin 1 interactome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Cigarette smoke total particulate matter increases mucous secreting cell numbers in vitro: a potential model of goblet cell hyperplasia

20 June 2018

1 reference

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Vagal control of mucociliary clearance in murine lungs: a study in a chronic preparation

20 June 2018

1 reference

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Mammalian autophagy: core molecular machinery and signaling regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Smoking is associated with shortened airway cilia

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

The ubiquitin conjugation system is involved in the disassembly of cilia and flagella

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Novel methods for measuring cardiac autophagy in vivo.

20 June 2018

1 reference

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Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Egr-1 regulates autophagy in cigarette smoke-induced chronic obstructive pulmonary disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Chemical and biological approaches synergize to ameliorate protein-folding diseases.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Autophagic proteins regulate cigarette smoke-induced apoptosis: protective role of heme oxygenase-1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Comprehensive high-throughput arrays for relative methylation (CHARM).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Autophagy in the Pathogenesis of Disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Mucociliary clearance as an outcome measure for cystic fibrosis clinical research

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

HEF1-dependent Aurora A activation induces disassembly of the primary cilium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

pVHL and GSK3beta are components of a primary cilium-maintenance signalling network

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Methods for monitoring autophagy from yeast to human

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Intraflagellar transport and cilium-based signaling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Therapeutic approaches to protein-misfolding diseases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Chronic obstructive pulmonary disease: molecular and cellularmechanisms

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. NHLBI/WHO Global Initiative for Chronic Obstructive Lung Disease (GOLD) Workshop summary

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Induction of autophagy and inhibition of tumorigenesis by beclin 1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Aggresomes: a cellular response to misfolded proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Hypomethylation of DNA: a possible epigenetic mechanism involved in tumor promotion

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Morphologic alterations induced by short-term cigarette smoking.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Studies on cilia. 3. Further studies on the cilium tip and a "sliding filament" model of ciliary motility

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Inhalation injury to tracheal epithelium in an ovine model of cotton smoke exposure. Early phase (30 minutes).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Phenylbutyric acid reduces amyloid plaques and rescues cognitive behavior in AD transgenic mice.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Inducible disruption of autophagy in the lung causes airway hyper-responsiveness.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Growth and differentiation of mouse tracheal epithelial cells: selection of a proliferative population.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3859407

Pulmonary function, oxidative stress and inflammatory markers in severe COPD exacerbation

26 November 2018

1 reference

12 December 2020

Selective autophagy: ubiquitin-mediated recognition and beyond

1 reference

12 December 2020

Smoke and viral infection cause cilia loss detectable by bronchoalveolar lavage cytology and dynein ELISA

1 reference

12 December 2020

Experimental effect of cigarette smoke on human respiratory cilia

1 reference

12 December 2020

Chronic obstructive pulmonary disease

1 reference

12 December 2020

Methodology for the measurement of mucociliary function in the mouse by scintigraphy

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI69636

1 reference

20 August 2017

1 reference

20 August 2017

1 reference