Predicting cancer drug mechanisms of action using molecular network signatures (Q30573575)

14 October 2017

Predicting cancer drug mechanisms of action using molecular network signatures (English)

1 reference

14 October 2017

Douglas A. Lauffenburger

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4

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Douglas A Lauffenburger

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14 October 2017

Justin R Pritchard

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14 October 2017

Peter M Bruno

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2

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14 October 2017

Michael T Hemann

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3

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14 October 2017

language of work or name

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4 January 2013

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14 October 2017

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14 October 2017

9

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14 October 2017

7

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14 October 2017

1604-1619

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Modulatory profiling identifies mechanisms of small molecule-induced cell death.

14 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

A mammalian functional-genetic approach to characterizing cancer therapeutics

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Cytoscape 2.8: new features for data integration and network visualization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Discovery of drug mode of action and drug repositioning from transcriptional responses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Zebrafish behavioral profiling links drugs to biological targets and rest/wake regulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Using sequence similarity networks for visualization of relationships across diverse protein superfamilies.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Stromal gene signatures in large-B-cell lymphomas

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Drug target identification using side-effect similarity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

High-content single-cell drug screening with phosphospecific flow cytometry

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Network-based classification of breast cancer metastasis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Gene expression profiling predicts clinical outcome of breast cancer

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Functional discovery via a compendium of expression profiles

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Characterization of a novel zinc finger gene (ZNF165) mapping to 6p21 that is expressed specifically in testis

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

Display and analysis of patterns of differential activity of drugs against human tumor cell lines: development of mean graph and COMPARE algorithm.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3945388

A Decision-Theoretic Generalization of On-Line Learning and an Application to Boosting

20 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC2MB25459J

Identification of small molecules enhancing autophagic function from drug network analysis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC2MB25459J

Exploring the Mode-of-Action of Bioactive Compounds by Chemical-Genetic Profiling in Yeast

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1039%2FC2MB25459J

21 January 2018

Identifiers

DOI

10.1039/C2MB25459J

1 reference

14 October 2017

1 reference

14 October 2017

PubMed publication ID

23287973

1 reference