Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis (Q30582338)

16 October 2017

Cofactor-dependent conformational heterogeneity of GAD65 and its role in autoimmunity and neurotransmitter homeostasis (English)

1 reference

16 October 2017

1 reference

19

1 reference

Mauricio Garcia de Souza Costa

16 October 2017

3

Mauricio G S Costa

1 reference

16 October 2017

Itamar Kass

1

0 references

Daniel Christ

Daniel Christ

15

0 references

Ashley Buckle

Ashley M Buckle

20

0 references

David Perahia

16

David Perahia

1 reference

16 October 2017

12

David Langley

0 references

author name string

David E Hoke

2

1 reference

16 October 2017

Cyril F Reboul

4

1 reference

16 October 2017

Benjamin T Porebski

5

1 reference

16 October 2017

Nathan P Cowieson

6

1 reference

16 October 2017

Hervé Leh

7

1 reference

16 October 2017

Eugenia Pennacchietti

8

1 reference

16 October 2017

Julia McCoey

9

1 reference

16 October 2017

Oded Kleifeld

10

1 reference

16 October 2017

Carla Borri Voltattorni

11

1 reference

16 October 2017

Brendan Roome

13

1 reference

16 October 2017

Ian R Mackay

14

1 reference

16 October 2017

Malcolm Buckle

17

1 reference

16 October 2017

Alessandro Paiardini

18

1 reference

16 October 2017

language of work or name

English

0 references

publication date

9 June 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

16 October 2017

1 reference

16 October 2017

111

1 reference

16 October 2017

25

1 reference

16 October 2017

E2524-9

1 reference

Structural characterization of the mechanism through which human glutamic acid decarboxylase auto-activates

16 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Open conformation of human DOPA decarboxylase reveals the mechanism of PLP addition to Group II decarboxylases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

An analysis of the cross-reactivity of autoantibodies to GAD65 and GAD67 in diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Characterisation of peptide microarrays for studying antibody-antigen binding using surface plasmon resonance imagery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Structural determinants of GAD antigenicity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Structural biology of the GAD autoantigen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Probing protein structure by limited proteolysis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Local changes in the catalytic site of mammalian histidine decarboxylase can affect its global conformation and stability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Cofactor and tryptophan accessibility and unfolding of brain glutamate decarboxylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Conformational epitopes on the diabetes autoantigen GAD65 identified by peptide phage display and molecular modeling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Structural characteristics of brain glutamate decarboxylase in relation to its interaction and activation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Regulation of gamma-aminobutyric acid synthesis in the brain

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Identification of a dominant epitope of glutamic acid decarboxylase (GAD-65) recognized by autoantibodies in stiff-man syndrome

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Multiple evolutionary origin of pyridoxal-5'-phosphate-dependent amino acid decarboxylases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Evidence for feedback regulation of glutamate decarboxylase by gamma-aminobutyric acid

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Antibodies to a 64,000 Mr human islet cell antigen precede the clinical onset of insulin-dependent diabetes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Monoclonal antibodies to glutamic acid decarboxylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Two genes encode distinct glutamate decarboxylases

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Two human glutamate decarboxylases, 65-kDa GAD and 67-kDa GAD, are each encoded by a single gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Human monoclonal islet cell antibodies from a patient with insulin-dependent diabetes mellitus reveal glutamate decarboxylase as the target antigen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

20 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403182111

Distinctive interactions in the holoenzyme formation for two isoforms of glutamate decarboxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403182111

Computational Methods for Studying Serpin Conformational Change and Structural Plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403182111

Consensus modes, a robust description of protein collective motions from multiple-minima normal mode analysis--application to the HIV-1 protease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1403182111

High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4078817

ATP binding to brain l-glutamate decarboxylase: A study by affinity chromatography

26 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24927554

12 December 2020

inferred from PubMed ID database lookup

Inactivation of brain glutamate decarboxylase and the effects of adenosine 5?-triphosphate and inorganic phosphate

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24927554

12 December 2020

inferred from PubMed ID database lookup

ATP's impact on the conformation and holoenzyme formation in relation to the regulation of brain glutamate decarboxylase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24927554

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.1403182111

1 reference

release_r24h25mq6bdqfcdq27ravdjike

16 October 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/r24h25mq6bdqfcdq27ravdjike

24 November 2022

mapped directly with Wikidata item

1 reference

16 October 2017

PubMed publication ID

24927554

1 reference