Loss of heterozygosity in tumor cells requires re-evaluation: the data are biased by the size-dependent differential sensitivity of allele detection (Q30584951)

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English	Loss of heterozygosity in tumor cells requires re-evaluation: the data are biased by the size-dependent differential sensitivity of allele detection	scientific article

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scholarly article

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Europe PubMed Central

25 June 2017

Loss of heterozygosity in tumor cells requires re-evaluation: the data are biased by the size-dependent differential sensitivity of allele detection (English)

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Europe PubMed Central

25 June 2017

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Liu J

1

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Europe PubMed Central

25 June 2017

Zabarovska VI

2

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Europe PubMed Central

25 June 2017

Braga E

3

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Europe PubMed Central

25 June 2017

Alimov A

4

1 reference

Europe PubMed Central

25 June 2017

Klein G

5

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Europe PubMed Central

25 June 2017

Zabarovsky ER

6

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Europe PubMed Central

25 June 2017

language of work or name

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publication date

1 November 1999

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Europe PubMed Central

25 June 2017

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Europe PubMed Central

25 June 2017

462

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Europe PubMed Central

25 June 2017

1-2

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Europe PubMed Central

25 June 2017

121-128

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Europe PubMed Central

25 June 2017

Molecular genetic investigation of sporadic renal cell carcinoma: analysis of allele loss on chromosomes 3p, 5q, 11p, 17 and 22

1 reference

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Somatic cell hybrid panel and NotI linking clones for physical mapping of human chromosome 3.

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Alu-PCR approach to isolating NotI-linking clones from the 3p14-p21 region frequently deleted in renal cell carcinoma.

1 reference

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Loss of chromosome arm 8p loci in prostate cancer: Mapping by quantitative allelic imbalance

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Delineation of two distinct deleted regions on chromosome 9 in human non-melanoma skin cancers

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Deletion mapping of chromosome 11 in carcinoma of the bladder.

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Frequent deletions of material from chromosome arm 1p in oligodendroglial tumors revealed by double-target fluorescence in situ hybridization and microsatellite analysis.

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Loss of heterozygosity on chromosome 9 in human breast cancer: Association with clinical variables and genetic changes at other chromosome regions

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APC gene mutations and allelic losses in sporadic ampullary tumours: evidence of genetic difference from tumours associated with familial adenomatous polyposis.

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Loss of heterozygosity on chromosome arm 16q in breast cancer metastases.

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Frequent loss of heterozygosity in the region of the D7S523 locus in advanced ovarian cancer

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Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients

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Homozygous deletion and frequent allelic loss of the 21q11.1-q21.1 region including the ANA gene in human lung carcinoma

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Loss of heterozygosity for the short arm of chromosome 7 in sporadic Wilms tumour.

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Distinct regions of allelic imbalance on chromosome 10q22-q26 in squamous cell carcinomas of the lung.

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Detailed deletion mapping suggests the involvement of a tumor suppressor gene at 17p13.3, distal to p53, in the pathogenesis of lung cancers.

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Fine deletion mapping of chromosome 8p in non-small-cell lung carcinoma.

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Optimizing comparative genomic hybridization for analysis of DNA sequence copy number changes in solid tumors

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Detailed deletion mapping of chromosome segment 17q12-21 in sporadic breast tumours

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Identification of three distinct regions of allelic deletions on the short arm of chromosome 8 in hepatocellular carcinoma

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Comparative allelotyping epithelial tumors of the short arm of human chromosome 3 in of four different types

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21 January 2018

Involvement of multiple loci on chromosome 3 in renal cell cancer development

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7 January 2021

Loss of heterozygosity on chromosome arm 3p in nasopharyngeal carcinoma

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A 3p21.3 region is preferentially eliminated from human chromosome 3/mouse microcell hybrids during tumor growth in SCID mice

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Rapid mapping of NotI linking clones with differential hybridization and Alu-PCR

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Trinucleotide repeats affect DNA replication in vivo

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Major role for a 3p21 region and lack of involvement of the t(3;8) breakpoint region in the development of renal cell carcinoma suggested by loss of heterozygosity analysis

1 reference

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7 January 2021

Loss of heterozygosity from the short arm of chromosome 8 is an early event in breast cancers

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Loss of chromosome 17 loci in prostate cancer detected by polymerase chain reaction quantitation of allelic markers

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Loss of heterozygosity at 9p21 loci and mutations of the MTS1 and MTS2 genes in human lung cancers

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Correlations of allelic imbalance of chromosome 14 with adverse prognostic parameters in 148 renal cell carcinomas

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Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization

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Allelic losses on 18q21 are associated with progression and metastasis in human prostate cancer

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Loss of heterozygosity of chromosome 13 in Merkel cell carcinoma

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Loss of heterozygosity at 11q23.1 in breast carcinomas: indication for involvement of a gene distal and close to ATM

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Allelic loss of the BRCA1 and BRCA2 genes and other regions on 17q and 13q in breast cancer among women from Taiwan (area of low incidence but early onset)

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Deletion mapping of chromosome 4q in hepatocellular carcinoma

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Loss of heterozygosity on chromosome 14 in nasopharyngeal carcinoma

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A common region of allelic loss on chromosome region 3p25.3-26.3 in nasopharyngeal carcinoma

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Differential loss of heterozygosity at 7q31.2 in follicular and papillary thyroid tumors

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Frequent loss of heterozygosity and three critical regions on the short arm of chromosome 8 in ovarian adenocarcinomas

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Allelic loss on chromosome 6Q in primary prostate cancer

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Chromosome loss is the most frequent mechanism contributing to HLA haplotype loss in human tumors

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A novel region of deletion on chromosome 6q23.3 spanning less than 500 Kb in high grade invasive epithelial ovarian cancer

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Frequent loss of heterozygosity at 1p36 in ovarian adenocarcinomas but the gene encoding p73 is unlikely to be the target

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Localization of tumor suppressor gene associated with distant metastasis of urinary bladder cancer to a 1-Mb interval on 8p22

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Refinement of the LOH region 1 at 11q23.1 deleted in human breast carcinomas and sublocalization of 11 expressed sequence tags within the refined region

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10.1016/S0014-5793(99)01523-9

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Europe PubMed Central

25 June 2017

1 reference

Europe PubMed Central

25 June 2017

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