p63 and p73: old members of a new family (Q30595453)

25 June 2017

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title

p63 and p73: old members of a new family (English)

1 reference

25 June 2017

M C Marin

1

1 reference

PubMed ID

10799748

25 June 2017

W G Kaelin

series ordinal

2

1 reference

PubMed ID

10799748

25 June 2017

language of work or name

English

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publication date

1 May 2000

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Biochimica et Biophysica Acta

25 June 2017

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25 June 2017

1470

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25 June 2017

3

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25 June 2017

M93-M100

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

25 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p63, a p53 homolog at 3q27-29, encodes multiple products with transactivating, death-inducing, and dominant-negative activities

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

A novel protein with strong homology to the tumor suppressor p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Cloning and functional analysis of human p51, which structurally and functionally resembles p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

A new human p53 homologue

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

T antigen is bound to a host protein in SY40-transformed cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Characterization of a 54K Dalton cellular SV40 tumor antigen present in SV40-transformed cells and uninfected embryonal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Structural aspects of the p53 protein in relation to gene evolution: a second look.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Negative feedback regulation of wild-type p53 biosynthesis.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Immunologically distinct p53 molecules generated by alternative splicing

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

The carboxyl-terminal domain of the p53 protein regulates sequence-specific DNA binding through its nonspecific nucleic acid-binding activity

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Alternatively spliced forms in the carboxy-terminal domain of the p53 protein regulate its ability to promote annealing of complementary single strands of nucleic acids

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Two new p73 splice variants, gamma and delta, with different transcriptional activity.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Alternatively spliced p53 RNA in transformed and normal cells of different tissue types

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Endogenous p53 protein generated from wild-type alternatively spliced p53 RNA in mouse epidermal cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

A leucine-rich nuclear export signal in the p53 tetramerization domain: regulation of subcellular localization and p53 activity by NES masking

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Viral oncoproteins discriminate between p53 and the p53 homolog p73.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 is a simian [correction of human] p53-related protein that can induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Promoter specificity and stability control of the p53-related protein p73

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

New p73 variants with altered C-terminal structures have varied transcriptional activities

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Heterozygous germline mutations in the p53 homolog p63 are the cause of EEC syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

There may be two tumor suppressor genes on chromosome arm 1p closely associated with biologically distinct subtypes of neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p53 Family members p63 and p73 are SAM domain-containing proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Predicting functions from protein sequences--where are the bottlenecks?

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Solution structure of a conserved C-terminal domain of p73 with structural homology to the SAM domain.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Different p73 splicing variants are expressed in distinct tumour areas of a multifocal neuroblastoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 and p63 are homotetramers capable of weak heterotypic interactions with each other but not with p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 function is inhibited by tumor-derived p53 mutants in mammalian cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Cancer. p53, guardian of the genome

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Adenovirus early region 1B 58,000-dalton tumor antigen is physically associated with an early region 4 25,000-dalton protein in productively infected cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

The large T antigen of simian virus 40 binds and inactivates p53 but not p73.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Distinct regulation of p53 and p73 activity by adenovirus E1A, E1B, and E4orf6 proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Failure of viral oncoproteins to target the p53-homologue p51A

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Tumor surveillance via the ARF-p53 pathway.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Post-Translational Regulation of the 54K Cellular Tumor Antigen in Normal and Transformed Cells

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

The p53-mdm-2 autoregulatory feedback loop

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Oncoprotein MDM2 conceals the activation domain of tumour suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mdm2 promotes the rapid degradation of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Regulation of p53 stability by Mdm2

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

MDM2 suppresses p73 function without promoting p73 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Inactivation of the p53-homologue p73 by the mdm2-oncoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mdm2 binds p73 alpha without targeting degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

MDM2 and MDMX bind and stabilize the p53-related protein p73

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p300/MDM2 complexes participate in MDM2-mediated p53 degradation

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Regulation of Mdm2-directed degradation by the C terminus of p53.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

1 reference

7 January 2021

p63 is essential for regenerative proliferation in limb, craniofacial and epithelial development

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p63 is a p53 homologue required for limb and epidermal morphogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 at chromosome 1p36.3 is lost in advanced stage neuroblastoma but its mutation is infrequent

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mutational analysis of the p73 gene in human breast cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mutation and expression analysis of the p73 gene in prostate cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Overexpression of the wild type p73 gene in human bladder cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Alterations of p73 preferentially occur in gastric adenocarcinomas with foveolar epithelial phenotype.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Absence of mutation of the p73 gene localized at chromosome 1p36.3 in hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

p73 mutations and expression in adult de novo acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Loss of imprinting and allele switching of p73 in renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

The expression of p73 is increased in lung cancer, independent of p53 gene alteration

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Mutational analysis of p51A/TAp63gamma, a p53 homolog, in non-small cell lung cancer and breast cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

Lack of p73 mutations and late occurrence of p73 allelic deletions in melanoma tissues and cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0304-419X%2800%2900010-X

7 January 2021

10.1016/S0304-419X(00)00010-X

Identifiers

DOI

1 reference

25 June 2017

1 reference

PubMed ID

10799748