Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes (Q30597186)

19 October 2017

Combining hypoxia and bioreactor hydrodynamics boosts induced pluripotent stem cell differentiation towards cardiomyocytes (English)

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stem cell differentiation

19 October 2017

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1 reference

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9

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19 October 2017

Margarida Serra

2

0 references

Catarina Brito

object named as

Catarina Brito

5

0 references

Paula Marques Alves

object named as

Paula M Alves

11

0 references

Jürgen Hescheler

8

object named as

Jürgen Hescheler

1 reference

19 October 2017

Cláudia Correia

1

1 reference

19 October 2017

Nuno Espinha

3

1 reference

19 October 2017

Marcos Sousa

4

1 reference

19 October 2017

Karsten Burkert

6

1 reference

19 October 2017

Yunjie Zheng

7

1 reference

19 October 2017

Tomo Sarić

10

1 reference

19 October 2017

1 December 2014

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Stem Cell Reviews and Reports

19 October 2017

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19 October 2017

10

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19 October 2017

6

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19 October 2017

786-801

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Creative Commons Attribution 4.0 International

19 October 2017

start time

15 July 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Cardiomyocyte regeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Electrophysiological integration and action potential properties of transplanted cardiomyocytes derived from induced pluripotent stem cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Scalable expansion of human induced pluripotent stem cells in the defined xeno-free E8 medium under adherent and suspension culture conditions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Making cardiomyocytes: how mechanical stimulation can influence differentiation of pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

The use of aggregates of purified cardiomyocytes derived from human ESCs for functional engraftment after myocardial infarction

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Structural and functional maturation of cardiomyocytes derived from human pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Selective elimination of human pluripotent stem cells by an oleate synthesis inhibitor discovered in a high-throughput screen

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Controlling self-renewal and differentiation of stem cells via mechanical cues.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Induced pluripotent stem cells for cardiac repair

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Extracellular matrix promotes highly efficient cardiac differentiation of human pluripotent stem cells: the matrix sandwich method

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Differentiation of human embryonic stem cells and induced pluripotent stem cells to cardiomyocytes: a methods overview

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Process engineering of human pluripotent stem cells for clinical application

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Clinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Electron microscopic study of mouse embryonic stem cell-derived cardiomyocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Induced pluripotent stem cells--opportunities for disease modelling and drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

SIRPA is a specific cell-surface marker for isolating cardiomyocytes derived from human pluripotent stem cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Embryonic stem cell-derived cardiomyocyte heterogeneity and the isolation of immature and committed cells for cardiac remodeling and regeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Cardiac differentiation of pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Role of mechanical factors in fate decisions of stem cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Scalable Production of Cardiomyocytes Derived from c-Myc Free Induced Pluripotent Stem Cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

iPS cells: a source of cardiac regeneration

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Biophysics and dynamics of natural and engineered stem cell microenvironments

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Nongenetic method for purifying stem cell-derived cardiomyocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Cardiomyocytes from human pluripotent stem cells in regenerative medicine and drug discovery

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Scalable stirred-suspension bioreactor culture of human pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Functional characterization of cardiomyocytes derived from murine induced pluripotent stem cells in vitro

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Generation of functional murine cardiac myocytes from induced pluripotent stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Effect of mechanical loading on three-dimensional cultures of embryonic stem cell-derived cardiomyocytes

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Expansion of undifferentiated murine embryonic stem cells as aggregates in suspension culture bioreactors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Effects of static and cyclic loading in regulating extracellular matrix synthesis by cardiovascular cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Regeneration gaps: observations on stem cells and cardiac repair

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Physiologic oxygen enhances human embryonic stem cell clonal recovery and reduces chromosomal abnormalities.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Increased cardiomyocyte differentiation from human embryonic stem cells in serum-free cultures

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Characterization and enrichment of cardiomyocytes derived from human embryonic stem cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes

20 June 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Development of a perfusion fed bioreactor for embryonic stem cell-derived cardiomyocyte generation: oxygen-mediated enhancement of cardiomyocyte output.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Generation of human embryonic stem cell-derived mesoderm and cardiac cells using size-specified aggregates in an oxygen-controlled bioreactor

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Synergistic effects of hypoxia and extracellular matrix cues in cardiomyogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Embryonic stem cells utilize reactive oxygen species as transducers of mechanical strain-induced cardiovascular differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Cyclic strain induces mouse embryonic stem cell differentiation into vascular smooth muscle cells by activating PDGF receptor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Mechanical strain regulates endothelial cell patterning in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Mechanical stimulation of cyclic tensile strain induces reduction of pluripotent related gene expressions via activation of Rho/ROCK and subsequent decreasing of AKT phosphorylation in human induced pluripotent stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Cardiomyocyte production in mass suspension culture: embryonic stem cells as a source for great amounts of functional cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Effects of shear stress on germ lineage specification of embryonic stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Identification of cell surface proteins for antibody-based selection of human embryonic stem cell-derived cardiomyocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Patterns of expression in the developing myocardium: towards a morphologically integrated transcriptional model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

Improving expansion of pluripotent human embryonic stem cells in perfused bioreactors through oxygen control

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12015-014-9533-0

The effect of cyclic strain on embryonic stem cell-derived cardiomyocytes

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Cardiac grafting of engineered heart tissue in syngenic rats.

26 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4225049

Differentiation of embryonic stem cells into cardiomyocytes in a compliant microfluidic system

26 November 2018

1 reference

12 December 2020

Chondrocyte differentiation is modulated by frequency and duration of cyclic compressive loading

1 reference

12 December 2020

A small molecule that promotes cardiac differentiation of human pluripotent stem cells under defined, cytokine- and xeno-free conditions

1 reference

12 December 2020

Effects of oxygen tension on the establishment and lactate dehydrogenase activity of murine embryonic stem cells

1 reference

12 December 2020

Oxygen tension in the oviduct and uterus of rhesus monkeys, hamsters and rabbits

1 reference

12 December 2020

Experimental characterization of flow conditions in 2- and 20-l bioreactors with wave-induced motion

1 reference

12 December 2020

10.1007/S12015-014-9533-0

Identifiers

DOI

1 reference

Dimensions Publication ID

19 October 2017

0 references

1 reference

19 October 2017

PubMed publication ID

25022569

1 reference