An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation (Q30604334)

19 October 2017

An MHC II-dependent activation loop between adipose tissue macrophages and CD4+ T cells controls obesity-induced inflammation (English)

1 reference

19 October 2017

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2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310975%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

Brian F. Zamarron

5

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5 June 2020

Kanakadurga Singer

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5 June 2020

Robert W O'Rourke

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5 June 2020

author name string

Kae Won Cho

1

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5 June 2020

Jennifer L DelProposto

3

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5 June 2020

Lynn Geletka

4

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5 June 2020

Gabriel Martinez-Santibanez

6

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5 June 2020

Kevin A Meyer

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5 June 2020

Carey N Lumeng

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5 June 2020

publication date

9 October 2014

1 reference

19 October 2017

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5 June 2020

volume

9

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5 June 2020

issue

2

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5 June 2020

page(s)

605-617

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RBP4 activates antigen-presenting cells, leading to adipose tissue inflammation and systemic insulin resistance

5 June 2020

cites work

1 reference

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Attenuated adipose tissue and skeletal muscle inflammation in obese mice with combined CD4+ and CD8+ T cell deficiency

20 June 2018

1 reference

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Flow cytometry analyses of adipose tissue macrophages.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Imaging white adipose tissue with confocal microscopy

20 June 2018

1 reference

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T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance

20 June 2018

1 reference

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Regulation of adipose tissue T cell subsets by Stat3 is crucial for diet-induced obesity and insulin resistance

20 June 2018

1 reference

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Immunological goings-on in visceral adipose tissue

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Association between specific adipose tissue CD4+ T-cell populations and insulin resistance in obese individuals.

20 June 2018

1 reference

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Improved insulin sensitivity despite increased visceral adiposity in mice deficient for the immune cell transcription factor T-bet

20 June 2018

1 reference

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Adipose tissue macrophages function as antigen-presenting cells and regulate adipose tissue CD4+ T cells in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Class II major histocompatibility complex plays an essential role in obesity-induced adipose inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Neuropeptide Y is produced by adipose tissue macrophages and regulates obesity-induced inflammation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

20 June 2018

1 reference

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Dynamic T cell-APC interactions sustain chronic inflammation in atherosclerosis

20 June 2018

1 reference

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Dendritic cells promote macrophage infiltration and comprise a substantial proportion of obesity-associated increases in CD11c+ cells in adipose tissue and liver

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Unexpected role for MHC II-peptide complexes in shaping CD8 T-cell expansion and differentiation in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Identification of adipose tissue dendritic cells correlated with obesity-associated insulin-resistance and inducing Th17 responses in mice and patients

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Systemic inflammation and insulin sensitivity in obese IFN-γ knockout mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Visceral adipose inflammation in obesity is associated with critical alterations in tregulatory cell numbers

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance

20 June 2018

1 reference

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Alternative macrophage activation and metabolism

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

T cell and APC dynamics in situ control the outcome of vaccination

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4252867

Normalization of obesity-associated insulin resistance through immunotherapy

20 June 2018

1 reference

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Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters

20 June 2018

1 reference

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Omental milky spots develop in the absence of lymphoid tissue-inducer cells and support B and T cell responses to peritoneal antigens

20 June 2018

1 reference

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Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy

20 June 2018

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Homeostasis of naive and memory T cells

20 June 2018

1 reference

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Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals

20 June 2018

1 reference

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CD4 T cells: fates, functions, and faults

20 June 2018

1 reference

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Interferon-gamma, a Th1 cytokine, regulates fat inflammation: a role for adaptive immunity in obesity

20 June 2018

1 reference

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

20 June 2018

1 reference

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Dendritic cells in a mature age.

20 June 2018

1 reference

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In vivo imaging of lymphocyte trafficking

20 June 2018

1 reference

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Adiponectin induces dendritic cell activation via PLCγ/JNK/NF-κB pathways, leading to Th1 and Th17 polarization.

20 June 2018

1 reference

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Leptin Promotes Differentiation and Survival of Human Dendritic Cells and Licenses Them for Th1 Priming

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25310975

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Protection from radiation-induced colitis requires MHC class II antigen expression by cells of hemopoietic origin

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25310975

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2014.09.004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310975%20AND%20SRC:MED&resulttype=core&format=json

5 June 2020

1 reference

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5 June 2020

PubMed publication ID

25310975

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25310975%20AND%20SRC:MED&resulttype=core&format=json