The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data (Q30664916)

26 June 2017

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title

The relevance of tissue angiotensin-converting enzyme: manifestations in mechanistic and endpoint data (English)

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26 June 2017

T Rabelink

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Heribert Schunkert

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object named as

H Schunkert

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K Swedberg

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T Lüscher

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ORCID Public Data File 2021

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author name string

V J Dzau

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26 June 2017

K Bernstein

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D Celermajer

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J Cohen

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B Dahlöf

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J Deanfield

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J Diez

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H Drexler

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R Ferrari

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W van Gilst

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L Hansson

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B Hornig

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A Husain

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C Johnston

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H Lazar

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E Lonn

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J Mancini

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A Mimran

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C Pepine

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W Remme

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L Ruilope

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M Ruzicka

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T Unger

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D Vaughan

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M Weber

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26 June 2017

Working Group on Tissue Angiotensin-converting enzyme, International Society of Cardiovascular Pharmacotherapy

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26 June 2017

language of work or name

English

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publication date

1 November 2001

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American Journal of Cardiology

26 June 2017

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88

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1L-20L

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9A

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Comparative properties of angiotensin-converting enzyme inhibitors: Relations with inhibition of tissue angiotensin-converting enzyme and potential clinical implications

26 June 2017

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Concentrations of angiotensin-converting enzyme in tissues of the rat.

7 January 2021

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The critical role of tissue angiotensin-converting enzyme as revealed by gene targeting in mice

7 January 2021

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Genetic mapping of a gene causing hypertension in the stroke-prone spontaneously hypertensive rat

7 January 2021

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Heart mass and blood pressure have separate genetic determinants in the New Zealand genetically hypertensive (GH) rat

7 January 2021

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An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels

7 January 2021

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Angiotensin-converting enzyme in the human heart. Effect of the deletion/insertion polymorphism

7 January 2021

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Polymorphism of the angiotensin-converting enzyme gene and cardiovascular disease

7 January 2021

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Deletion polymorphism in the gene for angiotensin-converting enzyme is a potent risk factor for myocardial infarction

7 January 2021

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Association between a deletion polymorphism of the angiotensin-converting-enzyme gene and left ventricular hypertrophy.

7 January 2021

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[ACE gene polymorphism and cardiovascular diseases]

7 January 2021

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DD genotype of the angiotensin-converting enzyme gene is a risk factor for left ventricular hypertrophy

7 January 2021

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A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease

7 January 2021

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Absence of association or genetic linkage between the angiotensin-converting-enzyme gene and left ventricular mass.

7 January 2021

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Controversial association of left ventricular hypertrophy and the ACE I/D polymorphism--is the mist clearing up?

7 January 2021

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Association of angiotensin-converting enzyme gene I/D polymorphism with change in left ventricular mass in response to physical training

7 January 2021

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Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction

7 January 2021

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Genetic basis of left ventricular remodeling after myocardial infarction

7 January 2021

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Cardiovascular end-organ damage in Ren-2 transgenic rats compared to spontaneously hypertensive rats

7 January 2021

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Context-dependent associations of the ACE I/D polymorphism with blood pressure

7 January 2021

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Angiotensin I-converting enzyme gene polymorphism, coronary artery disease and myocardial infarction. An angiographically controlled study

7 January 2021

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Fate of angiotensin I in the circulation

7 January 2021

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Increased rat cardiac angiotensin converting enzyme activity and mRNA expression in pressure overload left ventricular hypertrophy. Effects on coronary resistance, contractility, and relaxation

7 January 2021

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Localization of angiotensin converting enzyme in rat heart

7 January 2021

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Cellular distribution of angiotensin-converting enzyme after myocardial infarction

7 January 2021

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Effects of ACE inhibitors on circulating versus cardiac angiotensin II in volume overload-induced cardiac hypertrophy in rats

7 January 2021

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Expression of renin-angiotensin system components in the heart, kidneys, and lungs of rats with experimental heart failure

7 January 2021

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Tissue-specific activation of cardiac angiotensin converting enzyme in experimental heart failure

7 January 2021

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Increased cardiac angiotensin-converting enzyme in rats with chronic heart failure

7 January 2021

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Expression of angiotensin-converting enzyme in remaining viable myocytes of human ventricles after myocardial infarction

7 January 2021

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Activation of angiotensinogen and angiotensin-converting enzyme gene expression in the left ventricle of senescent rats

7 January 2021

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Local stress, not systemic factors, regulate gene expression of the cardiac renin-angiotensin system in vivo: a comprehensive study of all its components in the dog.

7 January 2021

1 reference

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Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro

7 January 2021

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Is there an internal cardiac renin-angiotensin system?

7 January 2021

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Reciprocal regulation of pulmonary and cardiac angiotensin-converting enzyme in rats with severe left ventricular hypertrophy

7 January 2021

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Aspects of molecular biology and biochemistry of the cardiac renin-angiotensin system

7 January 2021

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Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions.

7 January 2021

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Prorenin, renin, angiotensinogen, and angiotensin-converting enzyme in normal and failing human hearts. Evidence for renin binding

7 January 2021

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Selective activation of cardiac angiotensinogen gene expression in post-infarction ventricular remodeling in the rat

7 January 2021

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Distribution and functional significance of cardiac angiotensin converting enzyme in hypertrophied rat hearts

7 January 2021

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Angiotensin II formation in the intact human heart. Predominance of the angiotensin-converting enzyme pathway

7 January 2021

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Vascular angiotensin-converting enzyme expression regulates local angiotensin II.

7 January 2021

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Angiotensin II-forming pathways in normal and failing human hearts

7 January 2021

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Local angiotensin II generation in the rat heart: role of renin uptake.

7 January 2021

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Regulation of local angiotensin II formation in the human heart in the presence of interstitial fluid. Inhibition of chymase by protease inhibitors of interstitial fluid and of angiotensin-converting enzyme by Ang-(1-9) formed by heart carboxypeptid

7 January 2021

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ACE knockout mice - lessons for adult nephrology

7 January 2021

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Angiotensin I and II exert inotropic effects in atrial but not in ventricular human myocardium. An in vitro study under physiological experimental conditions

7 January 2021

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Angiotensin II–Induced Growth Responses in Isolated Adult Rat Hearts

7 January 2021

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Effects of long-term angiotensin converting enzyme inhibition on myocardial hypertrophy in experimental aortic stenosis in the rat

7 January 2021

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Blockade of the renin-angiotensin system in cardiac pressure-overload hypertrophy in rats

7 January 2021

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Important role of tissue angiotensin-converting enzyme activity in the pathogenesis of coronary vascular and myocardial structural changes induced by long-term blockade of nitric oxide synthesis in rats

7 January 2021

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Pathological hypertrophy and cardiac interstitium. Fibrosis and renin-angiotensin-aldosterone system

7 January 2021

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Cultured myofibroblasts generate angiotensin peptides de novo

7 January 2021

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Regulation of extracellular matrix proteins in pressure-overload cardiac hypertrophy: effects of angiotensin converting enzyme inhibition

7 January 2021

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Quinapril decreases myocardial accumulation of extracellular matrix components in spontaneously hypertensive rats

7 January 2021

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Communication between myocytes and fibroblasts in cardiac remodeling in angiotensin chimeric mice

7 January 2021

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Stretch-mediated release of angiotensin II induces myocyte apoptosis by activating p53 that enhances the local renin-angiotensin system and decreases the Bcl-2-to-Bax protein ratio in the cell

7 January 2021

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p53 Induces myocyte apoptosis via the activation of the renin-angiotensin system.

7 January 2021

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Cardiomyocyte apoptosis and cardiac angiotensin-converting enzyme in spontaneously hypertensive rats

7 January 2021

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Intracardiac angiotensin-converting enzyme inhibition improves diastolic function in patients with left ventricular hypertrophy due to aortic stenosis

7 January 2021

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Angiotensin-converting enzyme inhibition prolongs survival and modifies the transition to heart failure in rats with pressure overload hypertrophy due to ascending aortic stenosis

7 January 2021

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Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting enzyme

7 January 2021

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Direct myocardial and coronary effects of enalaprilat in patients with dilated cardiomyopathy: assessment by a bilateral intracoronary infusion technique.

7 January 2021

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Effects of quinapril, a new angiotensin converting enzyme inhibitor, on left ventricular failure and survival in the cardiomyopathic hamster. Hemodynamic, morphological, and biochemical correlates

7 January 2021

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Effects of enalapril on mortality in severe congestive heart failure. Results of the Cooperative North Scandinavian Enalapril Survival Study (CONSENSUS).

7 January 2021

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Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure

7 January 2021

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Glucocorticoids Induce Angiotensin-Converting Enzyme Expression in Vascular Smooth Muscle

7 January 2021

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Bovine angiotensin converting enzyme cDNA cloning and regulation. Increased expression during endothelial cell growth arrest

7 January 2021

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Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects.

7 January 2021

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Role of bradykinin in mediating vascular effects of angiotensin-converting enzyme inhibitors in humans

7 January 2021

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Effect of activation and inhibition of the renin-angiotensin system on plasma PAI-1

7 January 2021

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Clinical importance of coronary endothelial vasodilator dysfunction and therapeutic options

7 January 2021

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Endothelial dysfunction in human disease

7 January 2021

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Angiotensin II-mediated hypertension in the rat increases vascular superoxide production via membrane NADH/NADPH oxidase activation. Contribution to alterations of vasomotor tone

7 January 2021

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Increased accumulation of tissue ACE in human atherosclerotic coronary artery disease

7 January 2021

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Interaction of genetic deficiency of endothelial nitric oxide, gender, and pregnancy in vascular response to injury in mice

7 January 2021

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Dietary protein intake and the progressive nature of kidney disease: the role of hemodynamically mediated glomerular injury in the pathogenesis of progressive glomerular sclerosis in aging, renal ablation, and intrinsic renal disease

7 January 2021

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Glomerular hemodynamic changes vs. hypertrophy in experimental glomerular sclerosis

7 January 2021

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Dual effects of angiotensin II on the plasminogen/plasmin system in rat mesangial cells

7 January 2021

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Interactions of transforming growth factor-beta and angiotensin II in renal fibrosis

7 January 2021

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Proteinuria predicts stroke and other atherosclerotic vascular disease events in nondiabetic and non-insulin-dependent diabetic subjects

7 January 2021

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Predictors of the progression of renal insufficiency in patients with insulin-dependent diabetes and overt diabetic nephropathy

7 January 2021

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Effect of antihypertensive therapy on the kidney in patients with diabetes: a meta-regression analysis

7 January 2021

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Additive antiproteinuric effect of ACE inhibition and a low-protein diet in human renal disease

7 January 2021

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Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. UK Prospective Diabetes Study Group

7 January 2021

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Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial

7 January 2021

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Antihypertensive therapy in type 2 diabetes: implications of the appropriate blood pressure control in diabetes (ABCD) trial

7 January 2021

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Coronary heart disease incidence in NIDDM patients in the Helsinki Heart Study

7 January 2021

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Systolic blood pressure as a predictor for cardiovascular disease in diabetes. A 5-year longitudinal study

7 January 2021

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NIDDM and its metabolic control predict coronary heart disease in elderly subjects

7 January 2021

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The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group

7 January 2021

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Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy. Heart Outcomes Prevention Evaluation Study Investigators

7 January 2021

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Effect of the angiotensin-converting-enzyme inhibitor benazepril on the progression of chronic renal insufficiency. The Angiotensin-Converting-Enzyme Inhibition in Progressive Renal Insufficiency Study Group

7 January 2021

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A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure

7 January 2021

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The Effect of the Angiotensin-Converting–Enzyme Inhibitor Zofenopril on Mortality and Morbidity after Anterior Myocardial Infarction

7 January 2021

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Long-term ACE-inhibitor therapy in patients with heart failure or left-ventricular dysfunction: a systematic overview of data from individual patients. ACE-Inhibitor Myocardial Infarction Collaborative Group

7 January 2021

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Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. Collaborative Group on ACE Inhibitor Trials.

7 January 2021

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Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators

7 January 2021

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Effect of ACE inhibitor trandolapril on life expectancy of patients with reduced left-ventricular function after acute myocardial infarction. TRACE Study Group. Trandolapril Cardiac Evaluation

7 January 2021

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Effect of enalapril on myocardial infarction and unstable angina in patients with low ejection fractions

7 January 2021

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Effects of captopril on ischemic events after myocardial infarction. Results of the Survival and Ventricular Enlargement trial. SAVE Investigators

7 January 2021

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Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection

7 January 2021

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The QUinapril Ischemic Event Trial (QUIET) design and methods: evaluation of chronic ACE inhibitor therapy after coronary artery intervention

7 January 2021

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Angiotensin-converting enzyme inhibition as antiatherosclerotic therapy: no answer yet. QUIET Investigators. QUinapril Ischemic Event Trial

7 January 2021

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Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients

7 January 2021

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Angiotensin-converting enzyme inhibition with quinapril improves endothelial vasomotor dysfunction in patients with coronary artery disease. The TREND (Trial on Reversing ENdothelial Dysfunction) Study

7 January 2021

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Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)

7 January 2021

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Effects of ramipril on plasma fibrinolytic balance in patients with acute anterior myocardial infarction. HEART Study Investigators

7 January 2021

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Angiotensin II formation in human vasculature after chronic ACE inhibition: a prospective, randomized, placebo-controlled study. QUO VADIS Investigators

7 January 2021

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Prevention of events with angiotensin-converting enzyme inhibition (the PEACE study design). Prevention of Events with Angiotensin-Converting Enzyme Inhibition

7 January 2021

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Effects of captopril therapy on endogenous fibrinolysis in men with recent, uncomplicated myocardial infarction.

7 January 2021

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Long-term effects of cholesterol lowering and angiotensin-converting enzyme inhibition on coronary atherosclerosis: The Simvastatin/Enalapril Coronary Atherosclerosis Trial (SCAT).

7 January 2021

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Randomized, placebo-controlled trial of the angiotensin-converting enzyme inhibitor, ramipril, in patients with coronary or other occlusive arterial disease

7 January 2021

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Effects of ramipril and vitamin E on atherosclerosis: the study to evaluate carotid ultrasound changes in patients treated with ramipril and vitamin E (SECURE).

7 January 2021

1 reference

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Converting enzyme inhibitors in cardiovascular therapy: current status and future potential

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Structural constraints of inhibitors for binding at two active sites on somatic angiotensin converting enzyme

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Characterization of cardiac angiotensin converting enzyme (ACE) and in vivo inhibition following oral quinapril to rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

The cardiac renin-angiotensin system in heart failure.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Measurement of angiotensin I converting enzyme inhibition in the heart

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Inhibition of angiotensin-converting enzyme (ACE) in plasma and tissue.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Functional importance of angiotensin-converting enzyme-dependent in situ angiotensin II generation in the human forearm

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Angiotensin-converting enzyme-independent contraction to angiotensin I in human resistance arteries.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Effect of enalaprilat on nitric oxide activity in coronary artery disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Differential effects of quinaprilat and enalaprilat on endothelial function of conduit arteries in patients with chronic heart failure

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Effect of enalapril and quinapril on forearm vascular ACE in man.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Ramipril prevents endothelial dysfunction induced by oxidized low-density lipoproteins: a bradykinin-dependent mechanism

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Ramiprilat prevents the development of acute coronary endothelial dysfunction in the dog.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

ACE inhibition accelerates endothelial regrowth in vivo: a possible explanation for the benefit observed with ACE inhibitors following arterial injury.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Increased NADH-Oxidase–Mediated Superoxide Production in the Early Stages of Atherosclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Mechanism by which quinapril improves vascular function in coronary artery disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Improvement in endothelial function by angiotensin converting enzyme inhibition in insulin-dependent diabetes mellitus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Tissue inhibition of angiotensin-converting enzyme activity stimulates angiogenesis in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Tissue angiotensin converting enzyme in cardiac and vascular hypertrophy, repair, and remodeling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Angiotensin-Converting Enzyme Inhibitors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

Control of hypertension with the angiotensin converting enzyme inhibitor captopril reduces glomerular proteinuria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Indications for ACE inhibitors in the early treatment of acute myocardial infarction: systematic overview of individual data from 100,000 patients in randomized trials. ACE Inhibitor Myocardial Infarction Collaborative Group

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9149%2801%2901878-1

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0002-9149(01)01878-1

1 reference

26 June 2017

1 reference