Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing. (Q30677297)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26296891%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

title

Rapid fine conformational epitope mapping using comprehensive mutagenesis and deep sequencing (English)

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22 February 2020

2

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22 February 2020

Aritro Nath

3

1 reference

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22 February 2020

Timothy A Whitehead

11

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ORCID Public Data File 2021

author name string

Caitlin A Kowalsky

1

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22 February 2020

Hailey E Dann

4

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22 February 2020

Vince W Kelly

5

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22 February 2020

Li Liu

6

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22 February 2020

Purva Shanker

7

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22 February 2020

Ellen K Wagner

8

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22 February 2020

Jennifer A Maynard

9

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22 February 2020

Christina Chan

10

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22 February 2020

language of work or name

English

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publication date

20 August 2015

1 reference

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Journal of Biological Chemistry

22 February 2020

published in

1 reference

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22 February 2020

volume

290

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22 February 2020

issue

44

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22 February 2020

page(s)

26457-26470

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High-resolution epitope mapping by HX MS reveals the pathogenic mechanism and a possible therapy for autoimmune TTP syndrome.

22 February 2020

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20 June 2018

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High-resolution sequence-function mapping of full-length proteins

20 June 2018

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Trop2: from development to disease

20 June 2018

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Precise and efficient antibody epitope determination through library design, yeast display and next-generation sequencing

20 June 2018

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Crystal structure and its bearing towards an understanding of key biological functions of EpCAM

20 June 2018

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Deep mutational scanning: a new style of protein science

20 June 2018

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High-resolution antibody dynamics of vaccine-induced immune responses

20 June 2018

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Proof of principle for epitope-focused vaccine design

20 June 2018

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The promise and challenge of high-throughput sequencing of the antibody repertoire.

20 June 2018

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Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

20 June 2018

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IPAF inflammasome is involved in interleukin-1β production from astrocytes, induced by palmitate; implications for Alzheimer's Disease

20 June 2018

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Curcumin-induced upregulation of the anti-tau cochaperone BAG2 in primary rat cortical neurons

20 June 2018

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Structure of RSV Fusion Glycoprotein Trimer Bound to a Prefusion-Specific Neutralizing Antibody

20 June 2018

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A multi-layer inference approach to reconstruct condition-specific genes and their regulation

20 June 2018

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Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies

20 June 2018

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Structural Basis for Treating Tumor Necrosis Factor (TNF )-associated Diseases with the Therapeutic Antibody Infliximab

20 June 2018

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Quantitative, solution-phase profiling of multiple transcription factors in parallel.

20 June 2018

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PFunkel: efficient, expansive, user-defined mutagenesis.

20 June 2018

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Preparation of biologically active single-chain variable antibody fragments that target the HIV-1 gp120 V3 loop.

20 June 2018

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Antibody repertoire profiling using bacterial display identifies reactivity signatures of celiac disease.

20 June 2018

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Rapid conformational epitope mapping of anti-gp120 antibodies with a designed mutant panel displayed on yeast

20 June 2018

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Regulated proteolysis of Trop2 drives epithelial hyperplasia and stem cell self-renewal via β-catenin signaling

20 June 2018

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Optimization of affinity, specificity and function of designed influenza inhibitors using deep sequencing

20 June 2018

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Identification of novel targets for breast cancer by exploring gene switches on a genome scale

20 June 2018

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Rep-Seq: uncovering the immunological repertoire through next-generation sequencing.

20 June 2018

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Computational Design of Proteins Targeting the Conserved Stem Region of Influenza Hemagglutinin

20 June 2018

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cAMP initiates early phase neuron-like morphology changes and late phase neural differentiation in mesenchymal stem cells

20 June 2018

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Induction of broadly neutralizing H1N1 influenza antibodies by vaccination

20 June 2018

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Global, regional, and national causes of child mortality in 2008: a systematic analysis

20 June 2018

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Characterization of a key neutralizing epitope on pertussis toxin recognized by monoclonal antibody 1B7.

20 June 2018

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Structural and functional bases for broad-spectrum neutralization of avian and human influenza A viruses

20 June 2018

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Nuclear signalling by tumour-associated antigen EpCAM

20 June 2018

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Heterosubtypic neutralizing monoclonal antibodies cross-protective against H5N1 and H1N1 recovered from human IgM+ memory B cells

20 June 2018

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High expression of TROP2 correlates with poor prognosis in pancreatic cancer.

20 June 2018

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Isolating and engineering human antibodies using yeast surface display

20 June 2018

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Clinical significance of TROP2 expression in colorectal cancer

20 June 2018

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The SPOT-synthesis technique. Synthetic peptide arrays on membrane supports--principles and applications

20 June 2018

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Rapid mapping of protein functional epitopes by combinatorial alanine scanning

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646304

The crystal structure of pertussis toxin

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646304

Epitopes on the S1 subunit of pertussis toxin recognized by monoclonal antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4646304

Mapping of discontinuous conformational epitopes by amide hydrogen/deuterium exchange mass spectrometry and computational docking.

20 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.676635

Conformation-dependent epitopes recognized by prion protein antibodies probed using mutational scanning and deep sequencing

21 January 2018

1 reference

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Expression, purification, and in vitro refolding of a humanized single-chain Fv antibody against human CTLA4 (CD152).

21 January 2018

1 reference

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Mapping of the binding landscape for a picomolar protein-protein complex through computation and experiment

21 January 2018

1 reference

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Palmitate-activated astrocytes via serine palmitoyltransferase increase BACE1 in primary neurons by sphingomyelinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M115.676635

Biochemical and preliminary X-ray characterization of the tumor-associated calcium signal transducer 2 (Trop2) ectodomain.

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M115.676635

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26296891%20AND%20SRC:MED&resulttype=core&format=json

release_mpnaygrz4reo7ncqqbqybhvlyi

22 February 2020

Fatcat ID

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Fatcat

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mapped directly with Wikidata item

24 November 2022

based on heuristic

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26296891%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

26296891

1 reference