Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses (Q30708822)

13 August 2017

Secondary rearrangements and hypermutation generate sufficient B cell diversity to mount protective antiviral immunoglobulin responses (English)

1 reference

13 August 2017

M Cascalho

3

0 references

Ulrich Kalinke

object named as

U Kalinke

2

0 references

Rolf M. Zinkernagel

6

object named as

R M Zinkernagel

1 reference

13 August 2017

C López-Macías

1

1 reference

13 August 2017

M Wabl

4

1 reference

13 August 2017

H Hengartner

5

1 reference

13 August 2017

A Lamarre

7

1 reference

13 August 2017

language of work or name

English

0 references

publication date

1 June 1999

1 reference

Journal of Experimental Medicine

13 August 2017

1 reference

13 August 2017

189

1 reference

13 August 2017

11

1 reference

13 August 2017

1791-1798

1 reference

V(H) gene replacement occurs in the spleen and bone marrow of non-autoimmune quasi-monoclonal mice

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Receptor editing occurs frequently during normal B cell development.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Antigen receptor engagement turns off the V(D)J recombination machinery in human tonsil B cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

T-cell independent IgM and enduring protective IgG antibodies induced by chimeric measles viruses.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Self-reactive B lymphocytes overexpressing Bcl-xL escape negative selection and are tolerized by clonal anergy and receptor editing.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

V(D)J recombinase induction in splenic B lymphocytes is inhibited by antigen-receptor signalling

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Induction of protective cytotoxic T cell responses in the presence of high titers of virus-neutralizing antibodies: implications for passive and active immunization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Receptor editing in a transgenic mouse model: site, efficiency, and role in B cell tolerance and antibody diversification

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Reliable cloning of functional antibody variable domains from hybridomas and spleen cell repertoires employing a reengineered phage display system

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Monovalent single-chain Fv fragments and bivalent miniantibodies bound to vesicular stomatitis virus protect against lethal infection.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

B cells are exquisitely sensitive to central tolerance and receptor editing induced by ultralow affinity, membrane-bound antigen.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

20 June 2018

A quasi-monoclonal mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Mapping of the dominant neutralizing antigenic site of a virus using infected cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Deletion of the immunoglobulin kappa chain intron enhancer abolishes kappa chain gene rearrangement in cis but not lambda chain gene rearrangement in trans

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Receptor editing: an approach by autoreactive B cells to escape tolerance

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

B lymphocytes may escape tolerance by revising their antigen receptors

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Receptor editing in self-reactive bone marrow B cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Early high-affinity neutralizing anti-viral IgG responses without further overall improvements of affinity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

How many specific B cells are needed to protect against a virus?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Lymphocytic choriomeningitis virus. VI. Isolation of a glycoprotein mediating neutralization

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Protection against lethal viral infection by neutralizing and nonneutralizing monoclonal antibodies: distinct mechanisms of action in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Somatic generation of antibody diversity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Susceptibility to lymphocytic choriomeningitis virus isolates correlates directly with early and high cytotoxic T cell activity, as well as with footpad swelling reaction, and all three are regulated by H-2D

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Baculovirus expression vectors: the requirements for high level expression of proteins, including glycoproteins.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Mechanism of recovery from acute virus infection: treatment of lymphocytic choriomeningitis virus-infected mice with monoclonal antibodies reveals that Lyt-2+ T lymphocytes mediate clearance of virus and regulate the antiviral antibody response

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Antibody mediated suppression of secondary IgM response in nude mice against vesicular stomatitis virus

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Antibodies against the two serotypes of vesicular stomatitis virus measured by enzyme-linked immunosorbent assay: immunodominance of serotype-specific determinants and induction of asymmetrically cross-reactive antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well plates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Antiviral antibodies attenuate T-cell-mediated immunopathology following acute lymphocytic choriomeningitis virus infection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Mechanisms of antibody-mediated protection against lymphocytic choriomeningitis virus infection: mother-to-baby transfer of humoral protection

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

The Immune Response of the Mouse to Lymphocytic Choriomeningitis Virus. I. Circulating Antibodies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

The role of somatic mutation in the generation of the protective humoral immune response against vesicular stomatitis virus.

20 June 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Specific cytotoxic T cells eliminate B cells producing virus-neutralizing antibodies [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Analysis of heavy and light chain pairings indicates that receptor editing shapes the human antibody repertoire.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

V(D)J Recombination in Mature B Cells: A Mechanism for Altering Antibody Responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Secondary V(D)J recombination in B-1 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

VH gene replacement in hyperselected B cells of the quasimonoclonal mouse

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Impairment and delay of neutralizing antiviral antibody responses by virus-specific cytotoxic T cells

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Functional analysis of T lymphocyte subsets in antiviral host defense.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2193076

Thymus dependence of viral antigens

25 November 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Immunoglobulin heavy chain gene replacement: a mechanism of receptor editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Editing disease-associated autoantibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

V(D)J recombinase activity in a subset of germinal center B lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Monoclonal antibodies to lymphocytic choriomeningitis and pichinde viruses: Generation, characterization, and cross-reactivity with other arenaviruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

Immune receptor editing: revise and select

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.189.11.1791

21 January 2018

Identifiers

DOI

10.1084/JEM.189.11.1791

1 reference

13 August 2017

1 reference

13 August 2017

1 reference