Neuropathogenesis of central nervous system HIV-1 infection (Q30724585)

26 June 2017

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Neuropathogenesis of central nervous system HIV-1 infection (English)

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26 June 2017

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1

Dennis L Kolson

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26 June 2017

1 September 2002

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Clinics in laboratory medicine

26 June 2017

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26 June 2017

22

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26 June 2017

3

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26 June 2017

703-717

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The neuropathogenesis of HIV-1 infection

26 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Seminars in medicine of the Beth Israel Hospital, Boston. Dementia associated with the acquired immunodeficiency syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Perivascular macrophages are the primary cell type productively infected by simian immunodeficiency virus in the brains of macaques: implications for the neuropathogenesis of AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Clinical-neuropathologic correlation in HIV-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Isolation of HTLV-III from cerebrospinal fluid and neural tissues of patients with neurologic syndromes related to the acquired immunodeficiency syndrome.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Relationship between human immunodeficiency virus-associated dementia and viral load in cerebrospinal fluid and brain

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Plasma viral load and CD4 lymphocytes predict HIV-associated dementia and sensory neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neurological disorders during HIV-1 infection correlate with viral load in cerebrospinal fluid but not with virus phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Levels of human immunodeficiency virus type 1 RNA in cerebrospinal fluid correlate with AIDS dementia stage

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

The level of human immunodeficiency virus (HIV) type 1 RNA in cerebrospinal fluid as a marker of HIV encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Expression of pro- and anti-apoptosis gene products in brains from paediatric patients with HIV-1 encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Apoptosis induced by HIV-1 infection of the central nervous system

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal apoptosis in HIV infection in adults

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal apoptosis does not correlate with dementia in HIV infection but is related to microglial activation and axonal damage

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Programmed cell death in brains of HIV-1-positive AIDS and pre-AIDS patients

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Apoptotic neurons in brains from paediatric patients with HIV-1 encephalitis and progressive encephalopathy.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Pathology of HIV-1 infection of the central nervous system. A review

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Pathways to neuronal injury and apoptosis in HIV-associated dementia.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Correlation between neurological progression and astrocyte apoptosis in HIV-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Isolates of human immunodeficiency virus type 1 from the brain may constitute a special group of the AIDS virus

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Macrophage tropism of human immunodeficiency virus type 1 isolates from brain and lymphoid tissues predicts neurotropism independent of coreceptor specificity

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

HIV-1 entry into CD4+ cells is mediated by the chemokine receptor CC-CKR-5

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

CXCR-4 is expressed by primary macrophages and supports CCR5-independent infection by dual-tropic but not T-tropic isolates of human immunodeficiency virus type 1

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

In vivo evolution of HIV-1 co-receptor usage and sensitivity to chemokine-mediated suppression.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Varied tropism of HIV-1 isolates derived from different regions of adult brain cortex discriminate between patients with and without AIDS dementia complex (ADC): evidence for neurotropic HIV variants.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

HIV-1 V3 domain variation in brain and spleen of children with AIDS: tissue-specific evolution within host-determined quasispecies

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Distinct Populations of Human Immunodeficiency Virus Type 1 in Blood and Cerebrospinal Fluid

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Unique HIV type 1 V3 region sequences derived from six different regions of brain: region-specific evolution within host-determined quasispecies.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Differences in human immunodeficiency virus type 1 V3 sequences from patients with and without AIDS dementia complex

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Sequence analysis of the V3 loop in brain and spleen of patients with HIV encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

HIV type 1 V3 sequences and the development of dementia during AIDS.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Apoptosis induced by infection of primary brain cultures with diverse human immunodeficiency virus type 1 isolates: evidence for a role of the envelope.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Increased CCR5 affinity and reduced CCR5/CD4 dependence of a neurovirulent primary human immunodeficiency virus type 1 isolate.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal death induced by brain-derived human immunodeficiency virus type 1 envelope genes differs between demented and nondemented AIDS patients

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1 alpha is mediated by the chemokine receptor CXCR4.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Intracellular CXCR4 signaling, neuronal apoptosis and neuropathogenic mechanisms of HIV-1-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Expression of caspase-3 in brains from paediatric patients with HIV-1 encephalitis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Upregulation of bax protein levels in neurons following cerebral ischemia.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Human immunodeficiency virus type 1 and its coat protein gp120 induce apoptosis and activate JNK and ERK mitogen-activated protein kinases in human neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Study of receptor-mediated neurotoxins released by HIV-1-infected mononuclear phagocytes found in human brain

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Models of neuronal injury in AIDS: another role for the NMDA receptor?

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Memantine prevents HIV coat protein-induced neuronal injury in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Involvement of activated caspase-3-like proteases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Nitric oxide mediates glutamate neurotoxicity in primary cortical cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Reactive nitrogen intermediates in human neuropathology: an overview

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal cell killing by the envelope protein of HIV and its prevention by vasoactive intestinal peptide.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

HIV-1 envelope proteins gp120 and gp160 potentiate NMDA-induced [Ca2+]i increase, alter [Ca2+]i homeostasis and induce neurotoxicity in human embryonic neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neurotoxic effects of tumor necrosis factor alpha in primary human neuronal cultures are mediated by activation of the glutamate AMPA receptor subtype: implications for AIDS neuropathogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

In vitro evidence for a dual role of tumor necrosis factor-alpha in human immunodeficiency virus type 1 encephalopathy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Upregulated expression of Fas and Fas ligand in brain through the spectrum of HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Induction of HIV-1 replication in latently infected CD4+ T cells using a combination of cytokines

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Residual HIV-1 disease in the era of highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Latent reservoirs of HIV: obstacles to the eradication of virus

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Restoration of the immune system with anti-retroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Zidovudine treatment of the AIDS dementia complex: results of a placebo-controlled trial. AIDS Clinical Trials Group

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Effect of continuous intravenous infusion of zidovudine (AZT) in children with symptomatic HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Effects of zidovudine in 30 patients with mild to end-stage AIDS dementia complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Antiretroviral drugs and the central nervous system.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Highly active antiretroviral therapy reverses brain metabolite abnormalities in mild HIV dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Suppression of inflammatory neurotoxins by highly active antiretroviral therapy in human immunodeficiency virus-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Nomenclature and research case definitions for neurologic manifestations of human immunodeficiency virus-type 1 (HIV-1) infection. Report of a Working Group of the American Academy of Neurology AIDS Task Force

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Combination antiretroviral therapy improves psychomotor speed performance in HIV-seropositive homosexual men

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Changes to AIDS dementia complex in the era of highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Cerebrospinal fluid HIV RNA originates from both local CNS and systemic sources

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

A phase I/II trial of nimodipine for HIV-related neurologic complications.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Human immunodeficiency virus-associated dementia

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Neuronal injury associated with HIV-1: approaches to treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Immunologic NO synthase: elevation in severe AIDS dementia and induction by HIV-1 gp41.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Transdermal selegiline in HIV-associated cognitive impairment: pilot, placebo-controlled study.

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Expression of CX3CR1 chemokine receptors on neurons and their role in neuronal survival

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

Akt/Protein kinase B inhibits cell death by preventing the release of cytochrome c from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0272-2712%2802%2900009-4

7 January 2021

10.1016/S0272-2712(02)00009-4

Identifiers

DOI

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26 June 2017

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PubMed ID

12244593