Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. (Q30725547)

26 June 2017

Structure-based computational database screening, in vitro assay, and NMR assessment of compounds that target TAR RNA. (English)

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26 June 2017

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Kenneth E Lind

1

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26 June 2017

Zhihua Du

2

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26 June 2017

Koh Fujinaga

3

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26 June 2017

B Matija Peterlin

4

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26 June 2017

Thomas L James

5

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26 June 2017

1 February 2002

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26 June 2017

Chemistry and Biology

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26 June 2017

9

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26 June 2017

185-193

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26 June 2017

2

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Modulation of RNA function by aminoglycoside antibiotics

26 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structure-based discovery of ligands targeted to the RNA double helix.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Docking of cationic antibiotics to negatively charged pockets in RNA folds

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Identification of ligands for RNA targets via structure-based virtual screening: HIV-1 TAR.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Anti-termination of transcription within the long terminal repeat of HIV-1 by tat gene product

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Inhibitors of protein-RNA complexation that target the RNA: specific recognition of human immunodeficiency virus type 1 TAR RNA by small organic molecules

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

A new class of HIV-1 Tat antagonist acting through Tat-TAR inhibition

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Small molecules that selectively block RNA binding of HIV-1 Rev protein inhibit Rev function and viral production

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Aminoglycoside-arginine conjugates that bind TAR RNA: synthesis, characterization, and antiviral activity

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

ICM?A new method for protein modeling and design: Applications to docking and structure prediction from the distorted native conformation

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structure-based design of ligands for protein basic domains: application to the HIV-1 Tat protein

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Adaptive recognition by nucleic acid aptamers

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structure, recognition and adaptive binding in RNA aptamer complexes

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structural basis of ligand discrimination by two related RNA aptamers resolved by NMR spectroscopy

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

The 1.3 A crystal structure of a biotin-binding pseudoknot and the basis for RNA molecular recognition

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Molecular recognition in the FMN-RNA aptamer complex

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structural origins of gentamicin antibiotic action

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structural basis for recognition of the RNA major groove in the tau exon 10 splicing regulatory element by aminoglycoside antibiotics

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Saccharide-RNA recognition in an aminoglycoside antibiotic-RNA aptamer complex

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structural rearrangements of HIV-1 Tat-responsive RNA upon binding of neomycin B

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Structure of the A site of Escherichia coli 16S ribosomal RNA complexed with an aminoglycoside antibiotic

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Interlocking structural motifs mediate molecular discrimination by a theophylline-binding RNA

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Solution structure of the tobramycin-RNA aptamer complex

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Saccharide-RNA recognition in a complex formed between neomycin B and an RNA aptamer

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

An RNA motif that binds ATP.

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Functional requirements for specific ligand recognition by a biotin-binding RNA pseudoknot

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

A novel RNA motif for neomycin recognition

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Binding of neomycin to the TAR element of HIV-1 RNA induces dissociation of Tat protein by an allosteric mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

RNA sequence determinants for aminoglycoside binding to an A-site rRNA model oligonucleotide

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

High-resolution molecular discrimination by RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Specific binding of aminoglycoside antibiotics to RNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Analytical Debye-Huckel model for electrostatic potentials around dissolved DNA.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Drug-like properties and the causes of poor solubility and poor permeability

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Activity of phenothiazines against antibiotic-resistant Mycobacterium tuberculosis: a review supporting further studies that may elucidate the potential use of thioridazine as anti-tuberculosis therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Conformation of the TAR RNA-Arginine Complex by NMR Spectroscopy

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

Solution structure of the HIV-2 TAR-argininamide complex

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https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

NMRPipe: a multidimensional spectral processing system based on UNIX pipes

1 reference

https://api.crossref.org/works/10.1016%2FS1074-5521%2802%2900106-0

7 January 2021

10.1016/S1074-5521(02)00106-0

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26 June 2017

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