The Cys-67 residue of HLA-B27 influences cell surface stability, peptide specificity, and T-cell antigen presentation. (Q30754072)

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13 November 2019

title

The Cys-67 residue of HLA-B27 influences cell surface stability, peptide specificity, and T-cell antigen presentation (English)

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13 November 2019

1

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13 November 2019

Jesús Vázquez

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13 November 2019

author name string

Martí M

2

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13 November 2019

Camafeita E

4

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13 November 2019

Ogueta S

5

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13 November 2019

López de Castro JA

6

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language of work or name

English

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publication date

22 October 2001

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Journal of Biological Chemistry

13 November 2019

published in

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13 November 2019

volume

276

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13 November 2019

issue

52

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13 November 2019

page(s)

48740-48747

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Ankylosing spondylitis and HL-A 27.

13 November 2019

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Reiter's disease and HL-A 27.

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Guilt by association: HLA-B27 and ankylosing spondylitis

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The specificity of peptides bound to human histocompatibility leukocyte antigen (HLA)-B27 influences the prevalence of arthritis in HLA-B27 transgenic rats

21 January 2018

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Relevance of residue 116 of HLA-B27 in determining susceptibility to ankylosing spondylitis.

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HLA-B27-restricted CD8 T cells derived from synovial fluids of patients with reactive arthritis and ankylosing spondylitis

21 January 2018

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CD8(+) T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis

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The role of HLA-B27 in spondyloarthritis

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HLA-B27 misfolding: a solution to the spondyloarthropathy conundrum?

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Mutation of Cys-67 alters the thermodynamic stability of the human leukocyte antigen HLA0-B*2705.

21 January 2018

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Spontaneous inflammatory disease in transgenic rats expressing HLA-B27 and human beta 2m: an animal model of HLA-B27-associated human disorders

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Inflammatory disease in HLA-B27 transgenic rats

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In vitro mutagenesis of HLA-B27. Substitution of an unpaired cysteine residue in the alpha 1 domain causes loss of antibody-defined epitopes

21 January 2018

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Host resistance directed selectively against H-2-deficient lymphoma variants. Analysis of the mechanism

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Production of monoclonal antibodies to group A erythrocytes, HLA and other human cell surface antigens-new tools for genetic analysis

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Characterization of a monoclonal anti-beta 2-microglobulin antibody and its use in the genetic and biochemical analysis of major histocompatibility antigens

21 January 2018

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Limited diversity of peptides related to an alloreactive T cell epitope in the HLA-B27-bound peptide repertoire results from restrictions at multiple steps along the processing-loading pathway

21 January 2018

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Identification of novel HLA-B27 ligands derived from polymorphic regions of its own or other class I molecules based on direct generation by 20 S proteasome.

21 January 2018

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A single amino acid change makes the peptide specificity of B*3910 unrelated to B*3901 and closer to a group of HLA-B proteins including the malaria-protecting allotype HLA-B53.

21 January 2018

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Alloreactive cytolytic T cell clones with dual recognition of HLA-B27 and HLA-DR2 antigens. Selective involvement of CD8 in their class I--directed cytotoxicity

21 January 2018

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The origins of HLA-A,B,C polymorphism

21 January 2018

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The HLA-B73 antigen has a most unusual structure that defines a second lineage of HLA-B alleles

21 January 2018

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HLA-B73: an atypical HLA-B molecule carrying a Bw6-epitope motif variant and a B pocket identical to HLA-B27.

21 January 2018

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Chemical reactivity of an HLA-B27 thiol group

21 January 2018

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Homocysteine modification of HLA antigens and its immunological consequences

21 January 2018

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Crystal structures of two viral peptides in complex with murine MHC class I H-2Kb

21 January 2018

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Bound water structure and polymorphic amino acids act together to allow the binding of different peptides to MHC class I HLA-B53

21 January 2018

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Differences in endogenous peptides presented by HLA-B*2705 and B*2703 allelic variants. Implications for susceptibility to spondylarthropathies

21 January 2018

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Modulation of peptide binding by HLA-B27 polymorphism in pockets A and B, and peptide specificity of B*2703.

21 January 2018

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Pocket mutations of HLA-B27 show that anchor residues act cumulatively to stabilize peptide binding.

21 January 2018

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Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases

21 January 2018

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Association of class I major histocompatibility heavy and light chains induced by viral peptides

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HLA-B27 subtypes in Asian patients with ankylosing spondylitis. Evidence for new associations

21 January 2018

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Jekyll and Hyde: the transformation of HLA-B27

21 January 2018

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The three-dimensional structure of HLA-B27 at 2.1 A resolution suggests a general mechanism for tight peptide binding to MHC

21 January 2018

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21 January 2018

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Binding of peptides naturally presented by HLA-B27 to the differentially disease-associated B*2704 and B*2706 subtypes, and to mutants mimicking their polymorphism

21 January 2018

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Molecular analysis of the variant alloantigen HLA-B27d (HLA-B*2703) identifies a unique single amino acid substitution

21 January 2018

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Evidence that a single peptide-MHC complex on a target cell can elicit a cytolytic T cell response

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21 January 2018

Identifiers

DOI

10.1074/JBC.M108882200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11673468%20AND%20SRC:MED&resulttype=core&format=json

13 November 2019

1 reference