The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis (Q30784416)

26 June 2017

title

The R116C mutation in alpha A-crystallin diminishes its protective ability against stress-induced lens epithelial cell apoptosis (English)

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26 June 2017

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Usha P Andley

1

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26 June 2017

Harendra C Patel

series ordinal

2

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26 June 2017

Jing-Hua Xi

series ordinal

3

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26 June 2017

language of work or name

English

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publication date

27 December 2001

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Journal of Biological Chemistry

26 June 2017

published in

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26 June 2017

volume

277

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26 June 2017

issue

12

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26 June 2017

page(s)

10178-10186

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The function of alpha-crystallin in vision

26 June 2017

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The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

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A missense mutation in the alphaB-crystallin chaperone gene causes a desmin-related myopathy

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Mutation R120G in alphaB-crystallin, which is linked to a desmin-related myopathy, results in an irregular structure and defective chaperone-like function

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Comparative response to UV irradiation of cytoskeletal elements in rabbit and skate lens epithelial cells.

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Ultrastructural localization of alpha A-crystallin to the bovine lens fiber cell cytoskeleton

21 January 2018

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Alpha B-crystallin is expressed in non-lenticular tissues and accumulates in Alexander's disease brain

21 January 2018

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Signaling to chromatin through histone modifications

21 January 2018

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

21 January 2018

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Megabase chromatin domains involved in DNA double-strand breaks in vivo

21 January 2018

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Alpha-crystallin/small heat shock protein has autokinase activity

21 January 2018

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UV-induced changes in cell cycle and gene expression within rabbit lens epithelial cells

21 January 2018

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Protein kinase A-catalyzed phosphorylation of heat shock protein 60 chaperone regulates its attachment to histone 2B in the T lymphocyte plasma membrane

21 January 2018

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Identification of in vivo substrates of the chaperonin GroEL

21 January 2018

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Lens epithelial cells derived from alphaB-crystallin knockout mice demonstrate hyperproliferation and genomic instability

21 January 2018

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Cardiac alpha-crystallin. III. Involvement during heart ischemia

21 January 2018

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Insight into the secondary structure of non-native proteins bound to a molecular chaperone alpha-crystallin. An isotope-edited infrared spectroscopic study

21 January 2018

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The mode of chaperoning of dithiothreitol-denatured alpha-lactalbumin by alpha-crystallin

21 January 2018

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Synthesis and characterization of a peptide identified as a functional element in alphaA-crystallin

21 January 2018

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Structural and functional consequences of the mutation of a conserved arginine residue in alphaA and alphaB crystallins

21 January 2018

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Mutation of R116C results in highly oligomerized alpha A-crystallin with modified structure and defective chaperone-like function

21 January 2018

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Binding of actin to lens alpha crystallins

21 January 2018

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Association of alpha-crystallin with actin in cultured lens cells

21 January 2018

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alpha-crystallin stabilizes actin filaments and prevents cytochalasin-induced depolymerization in a phosphorylation-dependent manner

21 January 2018

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Histone H2B phosphorylation in mammalian apoptotic cells. An association with DNA fragmentation

21 January 2018

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21 January 2018

Identifiers

DOI

10.1074/JBC.M109211200

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26 June 2017

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