Germinal center B cells recognize antigen through a specialized immune synapse architecture. (Q30784700)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183103%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

title

Germinal center B cells recognize antigen through a specialized immune synapse architecture (English)

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3

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author name string

Carla R Nowosad

series ordinal

1

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1 April 2020

Katelyn M Spillane

series ordinal

2

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1 April 2020

language of work or name

English

0 references

publication date

16 May 2016

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1 April 2020

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1 April 2020

volume

17

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issue

7

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page(s)

870-877

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describes a project that uses

1 April 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4943528/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Germinal center B cell maintenance and differentiation are controlled by distinct NF-κB transcription factor subunits

20 June 2018

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Force generation in B-cell synapses: mechanisms coupling B-cell receptor binding to antigen internalization and affinity discrimination

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B cells use mechanical energy to discriminate antigen affinities

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B cell receptor signal transduction in the GC is short-circuited by high phosphatase activity

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WASp-deficient B cells play a critical, cell-intrinsic role in triggering autoimmunity

20 June 2018

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Germinal center dynamics revealed by multiphoton microscopy with a photoactivatable fluorescent reporter

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Antigen affinity discrimination is an intrinsic function of the B cell receptor.

20 June 2018

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Capture of influenza by medullary dendritic cells via SIGN-R1 is essential for humoral immunity in draining lymph nodes

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Integrated biochemical and computational approach identifies BCL6 direct target genes controlling multiple pathways in normal germinal center B cells.

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The constant region of the membrane immunoglobulin mediates B cell-receptor clustering and signaling in response to membrane antigens.

20 June 2018

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Phospholipase C-gamma2 and Vav cooperate within signaling microclusters to propagate B cell spreading in response to membrane-bound antigen

20 June 2018

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20 June 2018

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In vivo imaging of germinal centres reveals a dynamic open structure

20 June 2018

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B cells acquire antigen from target cells after synapse formation

20 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4943528

20 June 2018

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20 June 2018

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21 January 2018

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B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.

21 January 2018

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Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation.

21 January 2018

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Imaging of germinal center selection events during affinity maturation

21 January 2018

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Definition of germinal-center B cell migration in vivo reveals predominant intrazonal circulation patterns.

21 January 2018

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Multifocal structure of the T cell - dendritic cell synapse

21 January 2018

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Immature CD4(+)CD8(+) thymocytes form a multifocal immunological synapse with sustained tyrosine phosphorylation

21 January 2018

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A theory of germinal center B cell selection, division, and exit.

21 January 2018

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B cell activation is regulated by the stiffness properties of the substrate presenting the antigens.

21 January 2018

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Germinal center B cells govern their own fate via antibody feedback

21 January 2018

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Low-level hypermutation in T cell-independent germinal centers compared with high mutation rates associated with T cell-dependent germinal centers

21 January 2018

1 reference

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B cells acquire particulate antigen in a macrophage-rich area at the boundary between the follicle and the subcapsular sinus of the lymph node

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27183103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Extrafollicular activation of lymph node B cells by antigen-bearing dendritic cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27183103

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NI.3458

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183103%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27183103%20AND%20SRC:MED&resulttype=core&format=json

1 April 2020

1 reference