Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets (Q30784753)

8 November 2017

Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets (English)

1 reference

high-throughput screening

8 November 2017

0 references

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2

1 reference

8 November 2017

10

1 reference

8 November 2017

6

F Ulrich Hartl

1 reference

8 November 2017

Uwe Bertsch

1

1 reference

8 November 2017

Thomas Hirschberger

3

1 reference

8 November 2017

Jan Bieschke

4

1 reference

8 November 2017

Petra Weber

5

1 reference

8 November 2017

Paul Tavan

7

1 reference

8 November 2017

Hans A Kretzschmar

9

1 reference

8 November 2017

1 June 2005

1 reference

8 November 2017

1 reference

8 November 2017

79

1 reference

8 November 2017

12

1 reference

8 November 2017

7785-7791

1 reference

Misfolding of the prion protein at the plasma membrane induces endocytosis, intracellular retention and degradation

8 November 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

New inhibitors of scrapie-associated prion protein formation in a library of 2000 drugs and natural products

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Potent inhibition of scrapie prion replication in cultured cells by bis-acridines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Geldanamycin restores a defective heat shock response in vivo

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Intracellular re-routing of prion protein prevents propagation of PrP(Sc) and delays onset of prion disease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Prion-induced neuronal damage--the mechanisms of neuronal destruction in the subacute spongiform encephalopathies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Mimicking dominant negative inhibition of prion replication through structure-based drug design

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Porphyrin and phthalocyanine antiscrapie compounds.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Novel therapeutic uses for porphyrins and phthalocyanines in the transmissible spongiform encephalopathies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

A novel epitope for the specific detection of exogenous prion proteins in transgenic mice and transfected murine cell lines.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Rapid acquisition of beta-sheet structure in the prion protein prior to multimer formation

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Eight prion strains have PrP(Sc) molecules with different conformations

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Inhibition of protease-resistant prion protein formation by porphyrins and phthalocyanines

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Rapid assay processing by integration of dual-color fluorescence cross-correlation spectroscopy: high throughput screening for enzyme activity

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Kinetic investigations by fluorescence correlation spectroscopy: the analytical and diagnostic potential of diffusion studies

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Chemical chaperones interfere with the formation of scrapie prion protein

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

A new variant of Creutzfeldt-Jakob disease in the UK.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Congo red prolongs the incubation period in scrapie-infected hamsters.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Evidence for synthesis of scrapie prion proteins in the endocytic pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Evaluation of new cell culture inhibitors of protease-resistant prion protein against scrapie infection in mice

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Isolation of drugs active against mammalian prions using a yeast-based screening assay

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Inhibition of complex glycosylation increases the formation of PrPsc

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

A sensitive filter retention assay for the detection of PrP(Sc) and the screening of anti-prion compounds.

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Cationic Lipopolyamines Induce Degradation of PrPSc in Scrapie-Infected Mouse Neuroblastoma Cells

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent

25 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1143673

Effect of metal ions on de novo aggregation of full-length prion protein

25 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15919931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The scrapie-associated form of PrP is made from a cell surface precursor that is both protease- and phospholipase-sensitive

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15919931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Specific inhibition of in vitro formation of protease-resistant prion protein by synthetic peptides

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15919931

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/JVI.79.12.7785-7791.2005

1 reference

8 November 2017

1 reference

8 November 2017

PubMed publication ID

15919931

1 reference