Rational design of RGD-albumin conjugates for targeted delivery of the VEGF-R kinase inhibitor PTK787 to angiogenic endothelium. (Q30824639)

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30 December 2019

title

Rational design of RGD-albumin conjugates for targeted delivery of the VEGF-R kinase inhibitor PTK787 to angiogenic endothelium (English)

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30 December 2019

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4

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Grietje Molema

7

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8

Robbert J Kok

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30 December 2019

author name string

Kai Temming

1

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Marie Lacombe

2

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Roel Q J Schaapveld

3

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Gyorgy Kéri

5

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Klaas Poelstra

6

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publication date

1 November 2006

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volume

1

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issue

11

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page(s)

1200-1203

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Angiogenesis as a therapeutic target

30 December 2019

cites work

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7 January 2021

Update on angiogenesis inhibitors

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7 January 2021

Phase I study of the safety, tolerability, pharmacokinetics, and pharmacodynamics of PTK787/ZK 222584 administered twice daily in patients with advanced cancer

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Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416.

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Phase I study of antisense oligonucleotide against vascular endothelial growth factor: decrease in plasma vascular endothelial growth factor with potential clinical efficacy

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Cell attachment activity of fibronectin can be duplicated by small synthetic fragments of the molecule

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7 January 2021

RGD-based strategies for selective delivery of therapeutics and imaging agents to the tumour vasculature

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Development of vasculature targeting strategies for the treatment of cancer and chronic inflammatory diseases

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Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME).

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7 January 2021

Pharmacokinetic and biodistribution properties of poly(ethylene glycol)–protein conjugates

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7 January 2021

Preparation and functional evaluation of RGD-modified proteins as alpha(v)beta(3) integrin directed therapeutics.

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Identification of platination sites on human serum transferrin using 13C and 15N NMR spectroscopy

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7 January 2021

Effect of cis-, trans-diamminedichloroplatinum(II) and DBP on human serum albumin

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7 January 2021

Endothelial cells internalize and degrade RGD-modified proteins developed for tumor vasculature targeting

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7 January 2021

Selective targeting of pentoxifylline to hepatic stellate cells using a novel platinum-based linker technology.

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7 January 2021

Intracellular delivery of the p38 mitogen-activated protein kinase inhibitor SB202190 [4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)1H-imidazole] in renal tubular cells: a novel strategy to treat renal fibrosis

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7 January 2021

Identifiers

DOI

10.1002/CMDC.200600201

1 reference

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30 December 2019

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