Searching for drug targets in microbial genomes (Q30827586)

26 June 2017

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title

Searching for drug targets in microbial genomes (English)

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26 June 2017

1

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26 June 2017

2

Koonin EV

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26 June 2017

1 December 1999

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Current Opinion in Biotechnology

26 June 2017

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26 June 2017

10

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26 June 2017

6

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26 June 2017

571-578

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The complete genome sequence of Escherichia coli K-12

26 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Whole-genome random sequencing and assembly of Haemophilus influenzae Rd

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The complete genome sequence of the gastric pathogen Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The genome sequence of Rickettsia prowazekii and the origin of mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The complete genome sequence of the gram-positive bacterium Bacillus subtilis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The Minimal Gene Complement of Mycoplasma genitalium

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Complete sequence analysis of the genome of the bacterium Mycoplasma pneumoniae

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Complete Genome Sequence of Treponema pallidum, the Syphilis Spirochete

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Genome Sequence of an Obligate Intracellular Pathogen of Humans: Chlamydia trachomatis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Comparative genomes of Chlamydia pneumoniae and C. trachomatis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Implications of sequencing bacterial genomes for pathogenesis and vaccine development

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

In vivo expression technology for selection of bacterial genes specifically induced in host tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Antibiotic-based selection for bacterial genes that are specifically induced during infection of a host

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

DNA microarrays in drug discovery and development

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Sample sequencing of a Salmonella typhimurium LT2 lambda library: comparison to the Escherichia coli K12 genome

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

DNA sequencing and analysis of the low-Ca2+-response plasmid pCD1 of Yersinia pestis KIM5.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The complete DNA sequence and analysis of the large virulence plasmid of Escherichia coli O157:H7.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

"Black holes" and bacterial pathogenicity: a large genomic deletion that enhances the virulence of Shigella spp. and enteroinvasive Escherichia coli

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

PCR-based subtractive hybridization and differences in gene content among strains of Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Systematic identification of essential genes by in vitro mariner mutagenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

A minimal gene set for cellular life derived by comparison of complete bacterial genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

A genome-based approach for the identification of essential bacterial genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

A genomic perspective on protein families

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Beyond complete genomes: from sequence to structure and function

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The PROSITE database, its status in 1999

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Differential genome display

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Differential genome analysis applied to the species-specific features of Helicobacter pylori

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Molecular and cellular activities of Helicobacter pylori pathogenic factors

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Concordance analysis of microbial genomes

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Sequence analysis of an exceptionally conserved operon suggests enzymes for a new link between histidine and purine biosynthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The extremely conserved pyroA gene of Aspergillus nidulans is required for pyridoxine synthesis and is required indirectly for resistance to photosensitizers

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Eco Cyc: encyclopedia of Escherichia coli genes and metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Integrated pathway–genome databases and their role in drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Non-orthologous gene displacement

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Prokaryotic genomes: the emerging paradigm of genome-based microbiology

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Analogous enzymes: independent inventions in enzyme evolution

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The dhnA gene of Escherichia coli encodes a class I fructose bisphosphate aldolase

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The uraA locus and homologous recombination in Mycobacterium bovis BCG.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

The first genome from the third domain of life

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Eukaryotic transmembrane solute transport systems.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Rickettsiae and Chlamydiae: evidence of horizontal gene transfer and gene exchange

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Multidrug resistance: Versatile drug sensors of bacterial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Bacteria lacking a multidrug pump: a sensitive tool for drug discovery

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Reversal of tetracycline resistance mediated by different bacterial tetracycline resistance determinants by an inhibitor of the Tet(B) antiport protein.

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Learning from the genome sequence of Mycobacterium tuberculosis H37Rv

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

Archaeal-type lysyl-tRNA synthetase in the Lyme disease spirochete Borrelia burgdorferi

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

A superfamily of metalloenzymes unifies phosphopentomutase and cofactor-independent phosphoglycerate mutase with alkaline phosphatases and sulfatases

1 reference

https://api.crossref.org/works/10.1016%2FS0958-1669%2899%2900035-X

7 January 2021

10.1016/S0958-1669(99)00035-X

Identifiers

DOI

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26 June 2017

1 reference

PubMed ID

10600691