Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib (Q30873646)

13 October 2017

Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib (English)

1 reference

13 October 2017

chronic myeloid leukemia

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1 reference

1 reference

1 reference

Tessa Holyoake

4

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Franziska Michor

series ordinal

5

object named as

Franziska Michor

1 reference

13 October 2017

Jasmine Foo

1

1 reference

PMCID

2730033

13 October 2017

Mark W Drummond

series ordinal

2

1 reference

PMCID

2730033

13 October 2017

Bayard Clarkson

series ordinal

3

1 reference

13 October 2017

11 September 2009

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PLOS Computational Biology

13 October 2017

1 reference

13 October 2017

5

1 reference

13 October 2017

e1000503

1 reference

13 October 2017

9

1 reference

Creative Commons Attribution 4.0 International

13 October 2017

start time

11 September 2009

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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14 July 2018

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14 July 2018

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21 January 2018

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21 January 2018

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Successful therapy must eradicate cancer stem cells.

21 January 2018

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21 January 2018

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Chronic myeloid leukemia blast crisis arises from progenitors.

21 January 2018

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Intermittent exposure of primitive quiescent chronic myeloid leukemia cells to granulocyte-colony stimulating factor in vitro promotes their elimination by imatinib mesylate

21 January 2018

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High frequency of point mutations clustered within the adenosine triphosphate-binding region of BCR/ABL in patients with chronic myeloid leukemia or Ph-positive acute lymphoblastic leukemia who develop imatinib (STI571) resistance

21 January 2018

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Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis

21 January 2018

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Adaptive secretion of granulocyte-macrophage colony-stimulating factor (GM-CSF) mediates imatinib and nilotinib resistance in BCR/ABL+ progenitors via JAK-2/STAT-5 pathway activation

21 January 2018

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A pilot study of continuous imatinib vs pulsed imatinib with or without G-CSF in CML patients who have achieved a complete cytogenetic response.

21 January 2018

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25 November 2018

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A Quantitative Assay for the Number of Murine Lymphoma Cells capable of Proliferation in vivo

25 November 2018

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A primitive hematopoietic cell is the target for the leukemic transformation in human philadelphia-positive acute lymphoblastic leukemia

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19749982

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Quantitation of the quiescent fraction of long-term culture-initiating cells in normal human blood and marrow and the kinetics of their growth factor-stimulated entry into S-phase in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19749982

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PCBI.1000503

1 reference

journals/ploscb/FooDCHM09

13 October 2017

1 reference

DBLP Dataset 2021-01-02

28 January 2021

1 reference

13 October 2017

1 reference

PMCID

2730033