Strategies for discovering drugs from previously unexplored natural products (Q30880493)

27 June 2017

Strategies for discovering drugs from previously unexplored natural products (English)

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27 June 2017

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Harvey A

1

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27 June 2017

1 July 2000

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27 June 2017

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27 June 2017

5

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27 June 2017

7

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27 June 2017

294-300

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Natural products in drug discovery and development

27 June 2017

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Exploration of nature's chemodiversity: the role of secondary metabolites as leads in drug development

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Statistical Investigation into the Structural Complementarity of Natural Products and Synthetic Compounds

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

How many leads from HTS?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Will combinatorial chemistry deliver real medicines?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The role of natural products in a modern drug discovery program

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Natural product drug discovery and development: new perspectives on international collaboration

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The position of intellectual property rights in drug discovery and development from natural products

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Legal issues in sharing the benefits of biodiversity prospecting

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

When rhetoric hits reality in debate on bioprospecting

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

New rules for natural products research

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The Future of Biodiversity

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Plant polyphenols: biologically active compounds or non-selective binders to protein?

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

A method for quantitatively differentiating crude natural extracts using high-performance liquid chromatography-electrospray mass spectrometry

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Biodiversity prospecting in Nigeria: seeking equity and reciprocity in intellectual property rights through partnership arrangements and capacity building

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Molecular biological access to the chemistry of unknown soil microbes: a new frontier for natural products

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Biologically active fungal metabolites.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Perennial Antarctic lake ice: an oasis for life in a polar desert.

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Microorganisms in the accreted ice of Lake Vostok, Antarctica

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Poles apart: biodiversity and biogeography of sea ice bacteria

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Pyrolobus fumarii, gen. and sp. nov., represents a novel group of archaea, extending the upper temperature limit for life to 113 degrees C.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The complete genome of the hyperthermophilic bacterium Aquifex aeolicus

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Beutenbergia cavernae gen. nov., sp. nov., an L-lysine-containing actinomycete isolated from a cave.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Biodiversity in deep-sea sites located near the south part of Japan

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Marine species richness

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The marine biosphere: a global resource for biotechnology

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Adverse effects associated with the intrathecal administration of ziconotide

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Conopeptides: From deadly venoms to novel therapeutics

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

The T-superfamily of conotoxins.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Post-translationally modified neuropeptides from Conus venoms

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Cyclic peptides and depsipeptides from cyanobacteria: a review

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Induction of apoptosis by cryptophycin 1, a new antimicrotubule agent

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Curacin D, an antimitotic agent from the marine cyanobacterium Lyngbya majuscula

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

In vitro pharmacology of cryptophycin 52 (LY355703) in human tumor cell lines

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Use of plant roots for phytoremediation and molecular farming

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Genetically engineered synthesis of natural products: from alkaloids to corrins

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Cloning and heterologous expression of the epothilone gene cluster.

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Genetic construction and functional analysis of hybrid polyketide synthases containing heterologous acyl carrier proteins

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Novel macrolides through genetic engineering

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Rational design of aromatic polyketide natural products by recombinant assembly of enzymatic subunits

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Harnessing the biosynthetic code: combinations, permutations, and mutations

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Dissecting and exploiting intermodular communication in polyketide synthases

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

A study of iterative type II polyketide synthases, using bacterial genes cloned from soil DNA: a means to access and use genes from uncultured microorganisms

1 reference

https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Plant terpenoid synthases: molecular biology and phylogenetic analysis

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Plant natural products: the molecular genetic basis of biosynthetic diversity

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

Combinatorial biocatalysis: a natural approach to drug discovery

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https://api.crossref.org/works/10.1016%2FS1359-6446%2800%2901511-7

7 January 2021

10.1016/S1359-6446(00)01511-7

Identifiers

DOI

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27 June 2017

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PubMed ID

10856912