Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia (Q30883456)

27 June 2017

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title

Forward chemical genetics: progress and obstacles on the path to a new pharmacopoeia (English)

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27 June 2017

R Scott Lokey

1

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27 June 2017

1 February 2003

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Current Opinion in Chemical Biology

27 June 2017

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27 June 2017

7

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27 June 2017

1

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27 June 2017

91-96

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Towards a pharmacological genetics

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High-throughput method for the production and analysis of large natural product libraries for drug discovery

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Isolation of antibiotics turbomycin a and B from a metagenomic library of soil microbial DNA

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Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA.

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Cyclosporine A is an uncompetitive inhibitor of proteasome activity and prevents NF-kappaB activation.

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Identifiers

DOI

1 reference

27 June 2017

1 reference

PubMed ID

12547432