Estimating recombination rates from population-genetic data (Q30884546)

27 June 2017

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title

Estimating recombination rates from population-genetic data (English)

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27 June 2017

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1

Michael P H Stumpf

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27 June 2017

2

Gilean A T McVean

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27 June 2017

1 December 2003

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27 June 2017

Nature Reviews Genetics

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27 June 2017

4

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27 June 2017

959-968

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27 June 2017

12

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Linkage disequilibrium and the mapping of complex human traits.

27 June 2017

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Prospects for association-based fine mapping of a susceptibility gene for a complex disease.

21 January 2018

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High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot

21 January 2018

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Crossover breakpoint mapping identifies a subtelomeric hotspot for male meiotic recombination

21 January 2018

1 reference

Association study designs for complex diseases

21 January 2018

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Linkage disequilibrium in humans: models and data

21 January 2018

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Haplotype evolution and linkage disequilibrium: A simulation study

21 January 2018

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Distribution of recombination crossovers and the origin of haplotype blocks: the interplay of population history, recombination, and mutation

21 January 2018

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21 January 2018

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Expanding on population studies.

21 January 2018

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On selecting markers for association studies: patterns of linkage disequilibrium between two and three diallelic loci

21 January 2018

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Chromosome-wide distribution of haplotype blocks and the role of recombination hot spots

21 January 2018

1 reference

Using haplotype blocks to map human complex trait loci

21 January 2018

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The effect of single nucleotide polymorphism identification strategies on estimates of linkage disequilibrium

21 January 2018

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Correcting for ascertainment biases when analyzing SNP data: applications to the estimation of linkage disequilibrium

21 January 2018

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Likelihood analysis of disequilibrium mapping, and related problems

21 January 2018

1 reference

A coalescent approach to study linkage disequilibrium between single-nucleotide polymorphisms

21 January 2018

1 reference

Linkage disequilibrium: what history has to tell us.

21 January 2018

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Genealogical and evolutionary inference with the human Y chromosome

21 January 2018

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Coalescents and genealogical structure under neutrality.

21 January 2018

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Ancestral inference from samples of DNA sequences with recombination.

21 January 2018

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Recombination as a point process along sequences.

21 January 2018

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Inferences about Linkage Disequilibrium

21 January 2018

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On the minimum number of topologies explaining a sample of DNA sequences.

21 January 2018

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Evaluation of methods for detecting recombination from DNA sequences: computer simulations

21 January 2018

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A simulation study of the reliability of recombination detection methods.

21 January 2018

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Genealogical trees, coalescent theory and the analysis of genetic polymorphisms

21 January 2018

1 reference

Parsimony, likelihood, and the role of models in molecular phylogenetics.

21 January 2018

1 reference

Linkage disequilibrium in the human genome

21 January 2018

1 reference

The structure of haplotype blocks in the human genome

21 January 2018

1 reference

Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex

21 January 2018

1 reference

Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase

21 January 2018

1 reference

Consistency of estimators of the population-scaled recombination rate.

21 January 2018

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Patterns of linkage disequilibrium in the human genome

21 January 2018

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Demography, recombination hotspot intensity, and the block structure of linkage disequilibrium

21 January 2018

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Human genome sequence variation and the influence of gene history, mutation and recombination

21 January 2018

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Gene conversion and different population histories may explain the contrast between polymorphism and linkage disequilibrium levels

21 January 2018

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Detecting recent positive selection in the human genome from haplotype structure

21 January 2018

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21 January 2018

How clonal are bacteria?

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On the origin and evolution of the human immunodeficiency virus (HIV).

21 January 2018

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The evolutionary genomics of pathogen recombination

21 January 2018

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A likelihood method for the detection of selection and recombination using nucleotide sequences.

21 January 2018

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Simulating haplotype blocks in the human genome.

21 January 2018

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Genealogies and weak purifying selection.

21 January 2018

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Assessing the performance of the haplotype block model of linkage disequilibrium

21 January 2018

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Haplotype blocks and linkage disequilibrium in the human genome

21 January 2018

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Finding haplotype block boundaries by using the minimum-description-length principle

21 January 2018

1 reference

A New Statistical Method for Haplotype Reconstruction from Population Data

21 January 2018

1 reference

On the number of segregating sites in genetical models without recombination

21 January 2018

1 reference

Haplotype tagging for the identification of common disease genes

21 January 2018

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Family-based association studies

21 January 2018

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High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot

31 March 2020

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Prospects for whole-genome linkage disequilibrium mapping of common disease genes

31 March 2020

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The effects of local selection, balanced polymorphism and background selection on equilibrium patterns of genetic diversity in subdivided populations

31 March 2020

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Linkage disequilibrium mapping: the role of population history, size, and structure

31 March 2020

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A comparison of estimators of the population recombination rate

31 March 2020

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Haplotype diversity and the block structure of linkage disequilibrium

31 March 2020

1 reference

Why is there so little intragenic linkage disequilibrium in humans?

31 March 2020

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Estimating mutation rate and generation time from longitudinal samples of DNA sequences

31 March 2020

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Population bottlenecks and patterns of human polymorphism

31 March 2020

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The power to detect recombination using the coalescent

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1227

1 reference

PubMed ID

14631356

Dimensions Publication ID

27 June 2017

0 references

1 reference

PubMed ID

14631356