High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia (Q30885331)

19 August 2017

High expression of human beta S- and alpha-globins in transgenic mice: erythrocyte abnormalities, organ damage, and the effect of hypoxia (English)

1 reference

19 August 2017

1 reference

M. E. Fabry

1

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29 September 2022

F. Costantini

2

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29 September 2022

A. Pachnis

3

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29 September 2022

S. M. Suzuka

4

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29 September 2022

N. Bank

5

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29 September 2022

H. S. Aynedjian

6

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29 September 2022

S. M. Factor

7

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29 September 2022

R. L. Nagel

8

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29 September 2022

language of work or name

English

0 references

publication date

1 December 1992

1 reference

PMCID

50717

19 August 2017

15 December 1992

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=1465455

full work available at URL

29 September 2022

https://europepmc.org/articles/PMC50717

1 reference

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https://europepmc.org/articles/PMC50717?pdf=render

29 September 2022

file format

Portable Document Format

online access status

open access

content deliverer

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1465455

Proceedings of the National Academy of Sciences of the United States of America

29 September 2022

published in

1 reference

19 August 2017

89

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19 August 2017

24

1 reference

19 August 2017

12155-12159

1 reference

Abnormal adherence of sickle erythrocytes to cultured vascular endothelium: possible mechanism for microvascular occlusion in sickle cell disease

19 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

SC erythrocytes have an abnormally high intracellular hemoglobin concentration. Pathophysiological consequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Nuclear magnetic resonance imaging of the infarcted muscle: a rat model

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

A review of normal tissue hydrogen NMR relaxation times and relaxation mechanisms from 1-100 MHz: dependence on tissue type, NMR frequency, temperature, species, excision, and age.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

The relationship between proton nuclear magnetic resonance relaxation parameters and myocardial perfusion with acute coronary arterial occlusion and reperfusion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Urinary concentrating ability: insights from comparative anatomy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Acute splenic sequestration crises in adults with sickle cell disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Delay time of hemoglobin S polymerization prevents most cells from sickling in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Endothelial cell interactions with sickle cell, sickle trait, mechanically injured, and normal erythrocytes under controlled flow

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Introduction and expression of the human Bs-globin gene in transgenic mice.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Microvascular sites and characteristics of sickle cell adhesion to vascular endothelium in shear flow conditions: pathophysiological implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Hypoxia-induced in vivo sickling of transgenic mouse red cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Towards a transgenic mouse model of sickle cell disease: hemoglobin SAD.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

High expression of human beta S- and alpha-globins in transgenic mice: hemoglobin composition and hematological consequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

A micropuncture study of the effect of parathyroid hormone on renal bicarbonate reabsorption

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

Demonstration of endothelial adhesion of sickle cells in vivo: a distinct role for deformable sickle cell discocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=50717

MRI of the spleen: normal appearance and findings in sickle-cell anemia

25 November 2018

1 reference

12 December 2020

Renal hemodynamic studies in adults with sickle cell anemia

1 reference

12 December 2020

Rapid increase in red blood cell density driven by K:Cl cotransport in a subset of sickle cell anemia reticulocytes and discocytes

1 reference

12 December 2020

The unique red cell heterogeneity of SC disease: crystal formation, dense reticulocytes, and unusual morphology

1 reference

12 December 2020

Human sickle hemoglobin in transgenic mice

1 reference

12 December 2020

A transgenic mouse model of sickle cell disorder

1 reference

12 December 2020

Synthesis of functional human hemoglobin in transgenic mice

1 reference

12 December 2020

Mouse alpha chains inhibit polymerization of hemoglobin induced by human beta S or beta S Antilles chains

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.89.24.12155

1 reference

19 August 2017

0 references

1 reference

19 August 2017

1 reference

PMCID

50717