Identifying Novel Clinical Surrogates to Assess Human Bone Fracture Toughness (Q30886905)

30 October 2017

Identifying Novel Clinical Surrogates to Assess Human Bone Fracture Toughness (English)

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30 October 2017

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Mathilde Granke

1

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30 October 2017

Alexander J Makowski

2

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30 October 2017

Sasidhar Uppuganti

3

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30 October 2017

Mark D Does

4

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30 October 2017

Jeffry S Nyman

5

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30 October 2017

8 June 2015

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Journal of Bone and Mineral Research

30 October 2017

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30 October 2017

30

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30 October 2017

7

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30 October 2017

1290-1300

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The role of nanoscale toughening mechanisms in osteoporosis.

30 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Insights into reference point indentation involving human cortical bone: sensitivity to tissue anisotropy and mechanical behavior

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Magnetic resonance imaging assessed cortical porosity is highly correlated with μCT porosity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Research perspectives: The 2013 AAOS/ORS research symposium on Bone Quality and Fracture Prevention.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Bone cell-independent benefits of raloxifene on the skeleton: a novel mechanism for improving bone material properties

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Water residing in small ultrastructural spaces plays a critical role in the mechanical behavior of bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Bone metabolism and fracture risk in type 2 diabetes mellitus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Validation of quantitative bound- and pore-water imaging in cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

In vivo reference point indentation reveals positive effects of raloxifene on mechanical properties following 6 months of treatment in skeletally mature beagle dogs.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Partial removal of pore and loosely bound water by low-energy drying decreases cortical bone toughness in young and old donors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

High bone mineral density and fracture risk in type 2 diabetes as skeletal complications of inadequate glucose control: the Rotterdam Study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Micromechanical modeling of R-curve behaviors in human cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Atypical subtrochanteric femoral shaft fractures: role for mechanics and bone quality

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Fourier transform infrared imaging of femoral neck bone: reduced heterogeneity of mineral-to-matrix and carbonate-to-phosphate and more variable crystallinity in treatment-naive fracture cases compared with fracture-free controls

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Deuterium nuclear magnetic resonance unambiguously quantifies pore and collagen-bound water in cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Structural hierarchies define toughness and defect-tolerance despite simple and mechanically inferior brittle building blocks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Clinically compatible MRI strategies for discriminating bound and pore water in cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Quantitative ultrashort echo time (UTE) MRI of human cortical bone: correlation with porosity and biomechanical properties.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Reduced cortical bone compositional heterogeneity with bisphosphonate treatment in postmenopausal women with intertrochanteric and subtrochanteric fractures.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Ultrashort echo time spectroscopic imaging (UTESI): an efficient method for quantifying bound and free water

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Non-invasive predictors of human cortical bone mechanical properties: T(2)-discriminated H NMR compared with high resolution X-ray

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The relative contributions of non-enzymatic glycation and cortical porosity on the fracture toughness of aging bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Characterization of 1H NMR signal in human cortical bone for magnetic resonance imaging.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Structure and dynamics of water in native and tanned collagen fibers: Effect of crosslinking.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The significance of crack-resistance curves to the mixed-mode fracture toughness of human cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Microindentation for in vivo measurement of bone tissue mechanical properties in humans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Relating crack-tip deformation to mineralization and fracture resistance in human femur cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The bone diagnostic instrument II: indentation distance increase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Hierarchy of Bone Microdamage at Multiple Length Scales

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Failure of mineralized collagen fibrils: modeling the role of collagen cross-linking

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The role of cortical bone and its microstructure in bone strength.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The influence of water removal on the strength and toughness of cortical bone.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The relationship between bone mineral density and fracture risk

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

On the origin of the toughness of mineralized tissue: microcracking or crack bridging?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Is bone mineral density predictive of fracture risk reduction?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Influence of nonenzymatic glycation on biomechanical properties of cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Influence of microdamage on fracture toughness of the human femur and tibia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Influence of bone composition and apparent density on fracture toughness of the human femur and tibia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

The influence of bone morphology on fracture toughness of the human femur and tibia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Bone density and risk of hip fracture in men and women: cross sectional analysis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Advances in the fracture mechanics of cortical bone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Bone tissue: composition and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4478129

Proposed pathogenesis for atypical femoral fractures: lessons from materials research.

21 June 2018

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21 January 2018

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Effect of aging on the toughness of human cortical bone: evaluation by R-curves

21 January 2018

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Anisotropy of age-related toughness loss in human cortical bone: a finite element study.

21 January 2018

1 reference

Calculation of porosity and osteonal cement line effects on the effective fracture toughness of cortical bone in longitudinal crack growth

21 January 2018

1 reference

Accumulation of in-vivo fatigue microdamage and its relation to biomechanical properties in ageing human cortical bone

21 January 2018

1 reference

Microindentation for in vivo measurement of bone tissue material properties in atypical femoral fracture patients and controls.

21 January 2018

1 reference

Rising crack-growth-resistance behavior in cortical bone: implications for toughness measurements.

21 January 2018

1 reference

Reference point indentation study of age-related changes in porcine femoral cortical bone

21 January 2018

1 reference

21 January 2018

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Ductile sliding between mineral crystals followed by rupture of collagen crosslinks: experimentally supported micromechanical explanation of bone strength.

21 January 2018

1 reference

Intrafibrillar plasticity through mineral/collagen sliding is the dominant mechanism for the extreme toughness of antler bone.

21 January 2018

1 reference

Influence of the degradation of the organic matrix on the microscopic fracture behavior of trabecular bone

21 January 2018

1 reference

Fracture in human cortical bone: local fracture criteria and toughening mechanisms

21 January 2018

1 reference

Hierarchical interconnections in the nano-composite material bone: Fibrillar cross-links resist fracture on several length scales

21 January 2018

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Cement lines and interlamellar areas in compact bone as strain amplifiers - contributors to elasticity, fracture toughness and mechanotransduction

21 January 2018

1 reference

Fracture resistance of human cortical bone across multiple length-scales at physiological strain rates.

21 January 2018

1 reference

The increase in denaturation temperature following cross-linking of collagen is caused by dehydration of the fibres

21 January 2018

1 reference

Changes in the Stiffness, Strength, and Toughness of Human Cortical Bone With Age

21 January 2018

1 reference

Fracture toughness and work of fracture of hydrated, dehydrated, and ashed bovine bone

21 January 2018

1 reference

12 December 2020

Interaction of microstructure and microcrack growth in cortical bone: a finite element study

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12 December 2020

Single-column high-performance liquid chromatographic-fluorescence detection of immature, mature, and senescent cross-links of collagen

1 reference

12 December 2020

Experimental validation of a microcracking-based toughening mechanism for cortical bone

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12 December 2020

Effect of aging on the transverse toughness of human cortical bone: evaluation by R-curves

1 reference

12 December 2020

Microstructural heterogeneity and the fracture toughness of bone

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12 December 2020

Collagen and bone viscoelasticity: a dynamic mechanical analysis

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12 December 2020

Mechanistic aspects of the fracture toughness of elk antler bone

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12 December 2020

The true toughness of human cortical bone measured with realistically short cracks

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12 December 2020

Changes in the fracture toughness of bone may not be reflected in its mineral density, porosity, and tensile properties

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12 December 2020

Identifiers

DOI

10.1002/JBMR.2452

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30 October 2017

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30 October 2017

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