The paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter. (Q30900977)

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9 November 2019

title

The paired homeodomain transcription factor Pax-2 is expressed in the endocrine pancreas and transactivates the glucagon gene promoter (English)

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9 November 2019

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2

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9 November 2019

Benoit R Gauthier

series ordinal

3

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9 November 2019

author name string

B Ritz-Laser

series ordinal

1

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9 November 2019

J Philippe

series ordinal

4

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9 November 2019

language of work or name

English

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publication date

1 October 2000

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Journal of Biological Chemistry

9 November 2019

published in

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9 November 2019

volume

275

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9 November 2019

issue

42

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9 November 2019

page(s)

32708-32715

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Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila.

9 November 2019

cites work

1 reference

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Evolution of paired domains: isolation and sequencing of jellyfish and hydra Pax genes related to Pax-5 and Pax-6

21 January 2018

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Pax genes and organogenesis.

21 January 2018

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Mapping of Pax-2 transcription activation domains

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Genetic analysis reveals that PAX6 is required for normal transcription of pancreatic hormone genes and islet development

21 January 2018

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Pax-6 and Cdx-2/3 interact to activate glucagon gene expression on the G1 control element

21 January 2018

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Paired-homeodomain transcription factor PAX4 acts as a transcriptional repressor in early pancreatic development

21 January 2018

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Identification of a portable repression domain and an E1A-responsive activation domain in Pax4: a possible role of Pax4 as a transcriptional repressor in the pancreas

21 January 2018

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A novel Pax-6 binding site in rodent B1 repetitive elements: coevolution between developmental regulation and repeated elements?

21 January 2018

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Deregulation of Pax-2 expression in transgenic mice generates severe kidney abnormalities.

21 January 2018

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Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux.

21 January 2018

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The mouse Pax2(1Neu) mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye, and kidney

21 January 2018

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Islet-specific proteins interact with the insulin-response element of the glucagon gene

21 January 2018

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CAT vectors for analysis of eukaryotic promoters and enhancers.

21 January 2018

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Isolation of glucagon-secreting cell lines by cloning insulinoma cells

21 January 2018

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Establishment of a pancreatic beta cell line that retains glucose-inducible insulin secretion: special reference to expression of glucose transporter isoforms

21 January 2018

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Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor

21 January 2018

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Transformation of rat cells by DNA of human adenovirus 5

21 January 2018

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Expression of a human placental alkaline phosphatase gene in transfected cells: use as a reporter for studies of gene expression

21 January 2018

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

21 January 2018

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Insulin regulation of the glucagon gene is mediated by an insulin-responsive DNA element

21 January 2018

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Characterization of quail Pax-6 (Pax-QNR) proteins expressed in the neuroretina

21 January 2018

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Alternative splicing in PAX2 generates a new reading frame and an extended conserved coding region at the carboxy terminus

21 January 2018

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Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor

21 January 2018

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DNA-binding and transactivation properties of Pax-6: three amino acids in the paired domain are responsible for the different sequence recognition of Pax-6 and BSAP (Pax-5).

21 January 2018

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Identification of novel Pax-2 binding sites by chromatin precipitation

21 January 2018

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Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis

21 January 2018

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Differential regulation of the human Wilms tumour suppressor gene (WT1) promoter by two isoforms of PAX2

21 January 2018

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A binding site for Pax proteins regulates expression of the gene for the neural cell adhesion molecule in the embryonic spinal cord

21 January 2018

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Direct regulation of rhodopsin 1 by Pax-6/eyeless in Drosophila: evidence for a conserved function in photoreceptors

21 January 2018

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Alpha-cell-specific expression of the glucagon gene is conferred to the glucagon promoter element by the interactions of DNA-binding proteins

21 January 2018

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The Pax4 gene is essential for differentiation of insulin-producing β cells in the mammalian pancreas

21 January 2018

1 reference

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Pax6 is required for differentiation of glucagon-producing α-cells in mouse pancreas

21 January 2018

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Pax 4 and 6 regulate gastrointestinal endocrine cell development

21 January 2018

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Characterization of Pax-6 and Hoxa-1 binding to the promoter region of the neural cell adhesion molecule L1

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M005704200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:10938089%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference