Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants (Q30951164)

27 June 2017

Distinct promoters determine alternative transcription of gpx-4 into phospholipid-hydroperoxide glutathione peroxidase variants (English)

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27 June 2017

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Matilde Maiorino

1

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27 June 2017

Margherita Scapin

2

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27 June 2017

Fulvio Ursini

3

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27 June 2017

Mariangela Biasolo

4

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27 June 2017

Valentina Bosello

5

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27 June 2017

Leopold Flohé

6

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27 June 2017

language of work or name

English

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publication date

20 June 2003

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Journal of Biological Chemistry

27 June 2017

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27 June 2017

278

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27 June 2017

36

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27 June 2017

34286-34290

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Probing the presumed catalytic triad of selenium-containing peroxidases by mutational analysis of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

27 June 2017

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

The selenoenzyme phospholipid hydroperoxide glutathione peroxidase controls the activity of the 15-lipoxygenase with complex substrates and preserves the specificity of the oxygenation products

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Suppression of leukotriene formation in RBL-2H3 cells that overexpressed phospholipid hydroperoxide glutathione peroxidase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Mitochondrial phospholipid hydroperoxide glutathione peroxidase suppresses apoptosis mediated by a mitochondrial death pathway

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Interleukin-1-induced nuclear factor kappa B activation is inhibited by overexpression of phospholipid hydroperoxide glutathione peroxidase in a human endothelial cell line

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Dual function of the selenoprotein PHGPx during sperm maturation

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Versatility of selenium catalysis in PHGPx unraveled by LC/ESI-MS/MS.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Male fertility is linked to the selenoprotein phospholipid hydroperoxide glutathione peroxidase

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Genetic variations of gpx-4 and male infertility in humans

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Rat phospholipid-hydroperoxide glutathione peroxidase. cDNA cloning and identification of multiple transcription and translation start sites.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Testis-specific expression of the nuclear form of phospholipid hydroperoxide glutathione peroxidase (PHGPx).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Regulation of expression of the phospholipid hydroperoxide/sperm nucleus glutathione peroxidase gene. Tissue-specific expression pattern and identification of functional cis- and trans-regulatory elements.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Differential splicing of the phospholipid hydroperoxide glutathione peroxidase gene in diploid and haploid male germ cells in the rat.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Effect of hydrogen peroxide on calcium homeostasis in smooth muscle cells

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

Cloning of the mouse phospholipid hydroperoxide glutathione peroxidase gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Structural organization of the human selenium-dependent phospholipid hydroperoxide glutathione peroxidase gene (GPX4): chromosomal localization to 19p13.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Import into mitochondria of phospholipid hydroperoxide glutathione peroxidase requires a leader sequence.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M305327200

The CCAAT-box binding factor NF-Y is required for the expression of phospholipid hydroperoxide glutathione peroxidase in human epidermoid carcinoma A431 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Failure of the expression of phospholipid hydroperoxide glutathione peroxidase in the spermatozoa of human infertile males

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Inhibition of I kappa B-alpha phosphorylation and degradation and subsequent NF-kappa B activation by glutathione peroxidase overexpression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Microsomal lipid peroxidation: effect of vitamin E and its functional interaction with phospholipid hydroperoxide glutathione peroxidase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Purification and characterization of phospholipid hydroperoxide glutathione peroxidase from rat testis mitochondrial membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

Distribution and possible novel role of phospholipid hydroperoxide glutathione peroxidase in rat epididymal spermatozoa

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M305327200

21 January 2018

Identifiers

DOI

10.1074/JBC.M305327200

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27 June 2017

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