Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements (Q30973685)

27 June 2017

Identification of potential anticancer drug targets through the selection of growth-inhibitory genetic suppressor elements (English)

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27 June 2017

Thomas Primiano

1

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27 June 2017

Mirza Baig

2

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27 June 2017

Anil Maliyekkel

3

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27 June 2017

Bey Dih Chang

4

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27 June 2017

Stacey Fellars

5

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27 June 2017

Justin Sadhu

6

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27 June 2017

Sergey A Axenovich

7

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27 June 2017

Tatyana A Holzmayer

8

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27 June 2017

Igor B Roninson

9

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27 June 2017

1 July 2003

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27 June 2017

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27 June 2017

4

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27 June 2017

1

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27 June 2017

41-53

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Defective induction but normal activation and function of p53 in mouse cells lacking poly-ADP-ribose polymerase

27 June 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Differential requirements for alpha4 integrins during fetal and adult hematopoiesis

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Protein kinase Cepsilon is required for macrophage activation and defense against bacterial infection

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Inducible retroviral vectors regulated by lac repressor in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

p21Waf1/Cip1/Sdi1-induced growth arrest is associated with depletion of mitosis-control proteins and leads to abnormal mitosis and endoreduplication in recovering cells

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Errors in corticospinal axon guidance in mice lacking the neural cell adhesion molecule L1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of the glucocorticoid receptor gene blocks adrenergic chromaffin cell development and severely retards lung maturation

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

The 90-kDa molecular chaperone family: structure, function, and clinical applications. A comprehensive review

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Disruption of the mouse L1 gene leads to malformations of the nervous system

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Stimulation of Src family protein-tyrosine kinases as a proximal and mandatory step for SYK kinase-dependent phospholipase Cgamma2 activation in lymphoma B cells exposed to low energy electromagnetic fields

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Isolation of efficient antivirals: genetic suppressor elements against HIV-1.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Cloning mammalian genes by expression selection of genetic suppressor elements: association of kinesin with drug resistance and cell immortalization

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Transformation and Stat activation by derivatives of FGFR1, FGFR3, and FGFR4

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Isolation of dominant negative mutants and inhibitory antisense RNA sequences by expression selection of random DNA fragments

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

An ephrin-A-dependent signaling pathway controls integrin function and is linked to the tyrosine phosphorylation of a 120-kDa protein.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Normal development, wound healing, and adenovirus susceptibility in beta5-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Regulation of Fas expression by STAT3 and c-Jun is mediated by phosphatidylinositol 3-kinase-AKT signaling.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Pleiotropic effects of a null mutation in the c-fos proto-oncogene

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Activator protein-1 mediates induced but not basal epidermal growth factor receptor gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Src family kinases phosphorylate protein kinase C delta on tyrosine residues and modify the neoplastic phenotype of skin keratinocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Role of L1 in neural development: what the knockouts tell us.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Differentiation induction in human breast tumor cells by okadaic acid and related inhibitors of protein phosphatases 1 and 2A

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Initial sequencing and analysis of the human genome

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Exacerbated vein graft arteriosclerosis in protein kinase Cdelta-null mice

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of the zetaPKC gene results in the impairment of the NF-kappaB pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Internal ribosomal entry site-containing retroviral vectors with green fluorescent protein and drug resistance markers

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

A combination of genetic suppressor elements produces resistance to drugs inhibiting DNA replication

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

14-3-3 antagonizes Ras-mediated Raf-1 recruitment to the plasma membrane to maintain signaling fidelity

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Activation of NF-kappa B, AP-1 and STAT transcription factors is a frequent and early event in human hepatocellular carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Mouse mutants lacking the type 2 IGF receptor (IGF2R) are rescued from perinatal lethality in Igf2 and Igf1r null backgrounds

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Construction of a uniform-abundance (normalized) cDNA library

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Molecular portraits of human breast tumours

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Genetic selection of growth-inhibitory sequences in mammalian cells

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Isolation of growth suppressors from a cDNA expression library.

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

If not apoptosis, then what? Treatment-induced senescence and mitotic catastrophe in tumor cells

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https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

JunB is essential for mammalian placentation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Disruption of the Raf-1-Hsp90 Molecular Complex Results in Destabilization of Raf-1 and Loss of Raf-1-Ras Association

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

ERK signalling in metastatic human MDA-MB-231 breast carcinoma cells is adapted to obtain high urokinase expression and rapid cell proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Cytokine signaling: STATS in plasma membrane rafts

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of the p50 subunit of NF-kappa B leads to multifocal defects in immune responses

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Cyclin D1 provides a link between development and oncogenesis in the retina and breast.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

ZNF198-FGFR1 transforms Ba/F3 cells to growth factor independence and results in high level tyrosine phosphorylation of STATS 1 and 5

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

33258 Hoechst enhances the selectivity of the bromodeoxyuridine—light method of isolating conditional lethal mutants

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Sporozoites of Plasmodium yoelii infect mice with targeted deletions in ICAM-1 and ICAM-2 or complement components C3 and C4.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Targeted disruption of ATF4 discloses its essential role in the formation of eye lens fibres.

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Overexpression of the cell adhesion molecule L1 is associated with metastasis in cutaneous malignant melanoma

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Requirement of STAT5b for sexual dimorphism of body growth rates and liver gene expression

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

The Sequence of the Human Genome

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Extracellular ATP activates multiple signalling pathways and potentiates growth factor-induced c-fos gene expression in MCF-7 breast cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

Activation of the FGF receptor underlies neurite outgrowth stimulated by L1, N-CAM, and N-cadherin

1 reference

https://api.crossref.org/works/10.1016%2FS1535-6108%2803%2900169-7

7 January 2021

10.1016/S1535-6108(03)00169-7

Identifiers

DOI

1 reference

27 June 2017

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