Co-prescription of cytochrome P450 2D6/3A4 inhibitor-substrate pairs in clinical practice. A retrospective analysis of data from Norwegian primary pharmacies. (Q30982105)

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English	Co-prescription of cytochrome P450 2D6/3A4 inhibitor-substrate pairs in clinical practice. A retrospective analysis of data from Norwegian primary pharmacies.	scientific article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15692832%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Co-prescription of cytochrome P450 2D6/3A4 inhibitor-substrate pairs in clinical practice. A retrospective analysis of data from Norwegian primary pharmacies (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15692832%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Beate Hennie Garcia

2

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8 January 2020

author name string

Espen Molden

1

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8 January 2020

Pia Braathen

3

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8 January 2020

Anne Elise Eggen

4

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8 January 2020

publication date

4 February 2005

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8 January 2020

European Journal of Clinical Pharmacology

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Europe PubMed Central

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8 January 2020

61

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8 January 2020

2

1 reference

Europe PubMed Central

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8 January 2020

119-125

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15692832%20AND%20SRC:MED&resulttype=core&format=json

8 January 2020

Antipsychotic-related QTc prolongation, torsade de pointes and sudden death

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of clozapine and its major metabolites during combined treatment with paroxetine or sertraline

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diltiazem and mibefradil increase the plasma concentrations and greatly enhance the adrenal-suppressant effect of oral methylprednisolone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A potentially hazardous interaction between erythromycin and midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tacrolimus oral bioavailability doubles with coadministration of ketoconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Midazolam should be avoided in patients receiving the systemic antimycotics ketoconazole or itraconazole.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CYP2D6 inhibition by fluoxetine, paroxetine, sertraline, and venlafaxine in a crossover study: intraindividual variability and plasma concentration correlations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of the systemic antimycotics, itraconazole and fluconazole, on the pharmacokinetics and pharmacodynamics of intravenous and oral midazolam.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Change from the CYP2D6 extensive metabolizer to the poor metabolizer phenotype during treatment With bupropion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic and Pharmacodynamic Interactions of Oral Midazolam with Ketoconazole, Fluoxetine, Fluvoxamine, and Nefazodone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of risperidone metabolism by fluoxetine in patients with schizophrenia: a clinically relevant pharmacokinetic drug interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CYP2D6 in the stereoselective disposition of venlafaxine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state kinetics of fluoxetine and amitriptyline in patients treated with a combination of these drugs as compared with those treated with amitriptyline alone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of fluoxetine on the plasma concentrations of clozapine and its major metabolites in patients with schizophrenia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Erythromycin effects on multiple-dose carbamazepine kinetics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of codeine dependence with inhibitors of cytochrome P450 2D6

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of thioridazine, an inhibitor of CYP2D6, on the steady-state plasma concentrations of the enantiomers of mianserin and its active metabolite, desmethylmianserin, in depressed Japanese patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of methylprednisolone elimination in the presence of clarithromycin therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma buspirone concentrations are greatly increased by erythromycin and itraconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between midazolam and clarithromycin: comparison with azithromycin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Verapamil potentiates carbamazepine neurotoxicity: a clinically important inhibitory interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ketoconazole on methylprednisolone pharmacokinetics and cortisol secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A placebo-controlled trial of fluoxetine added to neuroleptic in patients with schizophrenia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nefazodone Inhibits Methylprednisolone Disposition and Enhances its Adrenal-Suppressant Effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P450 3A4 inhibitor itraconazole markedly increases the plasma concentrations of dexamethasone and enhances its adrenal-suppressant effect

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Paroxetine potentiates the central nervous system side effects of perphenazine: contribution of cytochrome P4502D6 inhibition in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole inhibition of triazolam and alprazolam clearance: differential kinetic and dynamic consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of quinidine on plasma and cerebrospinal fluid concentrations of codeine and morphine after codeine intake

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan and mephenytoin phenotyping of patients treated with thioridazine or amitriptyline

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dose of midazolam should be reduced during diltiazem and verapamil treatments

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interaction between single oral doses of diltiazem and sirolimus in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of the pharmacokinetics of cyclosporine A and metabolites by the concomitant use of Neoral and diltiazem or ketoconazol in stable adult kidney transplants

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole affects single-dose terfenadine pharmacokinetics and cardiac repolarization pharmacodynamics

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of terbinafine on the pharmacokinetics and pharmacodynamics of desipramine in healthy volunteers identified as cytochrome P450 2D6 (CYP2D6) extensive metabolizers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of cytochrome P4502D6 activity with paroxetine normalizes the ultrarapid metabolizer phenotype as measured by nortriptyline pharmacokinetics and the debrisoquin test

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FDA adverse event reports on statin-associated rhabdomyolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Steady-state pharmacokinetics and electrocardiographic pharmacodynamics of clarithromycin and loratadine after individual or concomitant administration

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interaction between fluoxetine and haloperidol: pharmacokinetic and clinical implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the pharmacokinetics and electrocardiographic pharmacodynamics of loratadine with concomitant administration of ketoconazole or cimetidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Elevation of plasma carbamazepine concentrations by ketoconazole in patients with epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Combining bupropion SR with venlafaxine, paroxetine, or fluoxetine: a preliminary report on pharmacokinetic, therapeutic, and sexual dysfunction effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinetic and dynamic study of oral alprazolam with and without erythromycin in humans: in vivo evidence for the involvement of CYP3A4 in alprazolam metabolism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coadministration of nefazodone and benzodiazepines: III. A pharmacokinetic interaction study with alprazolam

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Investigation of terbinafine as a CYP2D6 inhibitor in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dextromethorphan: enhancing its systemic availability by way of low-dose quinidine-mediated inhibition of cytochrome P4502D6.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zopiclone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loratadine administered concomitantly with erythromycin: pharmacokinetic and electrocardiographic evaluations

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The influence of cisapride and clarithromycin on QT intervals in healthy volunteers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ketoconazole inhibits the clearance of the enantiomers of the antidepressant reboxetine in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of erythromycin on the pharmacokinetics and pharmacodynamics of zopiclone

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The cytochrome P450 superfamily: biochemistry, evolution and drug metabolism in humans

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Terfenadine-ketoconazole interaction. Pharmacokinetic and electrocardiographic consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma concentrations of risperidone and 9-hydroxyrisperidone during combined treatment with paroxetine

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of methylprednisolone elimination in the presence of erythromycin therapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Carbamazepine-nefazodone interaction in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic interactions between microemulsion formulated cyclosporine A and diltiazem in renal transplant recipients

1 reference

https://pubmed.ncbi.nlm.nih.gov/15692832

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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