Directed evolution of proteins by exon shuffling (Q30988711)

28 June 2017

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title

Directed evolution of proteins by exon shuffling (English)

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28 June 2017

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Kolkman JA

1

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28 June 2017

Stemmer WP

series ordinal

2

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28 June 2017

publication date

1 May 2001

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28 June 2017

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28 June 2017

volume

19

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28 June 2017

issue

5

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28 June 2017

page(s)

423-428

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28 June 2017

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7 January 2021

Interaction of mutants of tissue-type plasminogen activator with liver cells: effect of domain deletions

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7 January 2021

The multiplicity of domains in proteins

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7 January 2021

Mechanisms of intron mobility.

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7 January 2021

Intron-dependent evolution: preferred types of exons and introns

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7 January 2021

Speculations on RNA splicing

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7 January 2021

Evolution of the proteases of blood coagulation and fibrinolysis by assembly from modules

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7 January 2021

The PAN module: the N-terminal domains of plasminogen and hepatocyte growth factor are homologous with the apple domains of the prekallikrein family and with a novel domain found in numerous nematode proteins

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7 January 2021

Characterization of the human factor VIII gene

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7 January 2021

Structure of the gene for human coagulation factor V

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7 January 2021

Nucleotide sequence of the gene for the b subunit of human factor XIII.

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7 January 2021

Construction and evolution of antibody-phage libraries by DNA shuffling

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7 January 2021

Replacing the first epidermal growth factor-like domain of factor IX with that of factor VII enhances activity in vitro and in canine hemophilia B.

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7 January 2021

Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization

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7 January 2021

The structure of the human tissue-type plasminogen activator gene: correlation of intron and exon structures to functional and structural domains

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7 January 2021

Gene for human factor X: a blood coagulation factor whose gene organization is essentially identical with that of factor IX and protein C.

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7 January 2021

Structural organization and the transcription initiation site of the human hepatocyte growth factor gene

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7 January 2021

Nucleotide sequence of the gene for human prothrombin

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7 January 2021

Organization of the fibronectin gene provides evidence for exon shuffling during evolution.

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7 January 2021

Organization of the gene encoding the human macrophage mannose receptor (mrc1)

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7 January 2021

Multiple sites of alternative splicing of the rat fibronectin gene transcript

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7 January 2021

The gene of chicken axonin-1. Complete structure and analysis of the promoter.

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7 January 2021

Structure of the X-linked Kallmann syndrome gene and its homologous pseudogene on the Y chromosome

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7 January 2021

Gene structure and chromosomal localization of plasma kallikrein

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7 January 2021

Organization of the gene for human factor XI.

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7 January 2021

Organization of the human protein S genes

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7 January 2021

Molecular analysis of the gene for vitamin K dependent protein S and its pseudogene. Cloning and partial gene organization

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7 January 2021

Intron-exon organization of the active human protein S gene PS alpha and its pseudogene PS beta: duplication and silencing during primate evolution

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7 January 2021

Structural organization of the human type VII collagen gene (COL7A1), composed of more exons than any previously characterized gene

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7 January 2021

Sequences of the genes and polypeptide precursors for two bovine protease inhibitors

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7 January 2021

Primary structure of the human follistatin precursor and its genomic organization

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7 January 2021

Structure of human osteonectin based upon analysis of cDNA and genomic sequences

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7 January 2021

Characterization of the murine thrombospondin gene

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7 January 2021

Mouse fibulin-2 gene. Complete exon-intron organization and promoter characterization

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7 January 2021

Structural organization and genetic localization of the human bone morphogenetic protein 1/mammalian tolloid gene

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7 January 2021

Genomic organization of human neuropilin-1 and neuropilin-2 genes: identification and distribution of splice variants and soluble isoforms

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7 January 2021

Genomic sequences and structural organization of the human nidogen gene (NID).

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7 January 2021

Structural organization of the 5' region of the thyroglobulin gene. Evidence for intron loss and "exonization" during evolution

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7 January 2021

Retroposition in a family of carcinoma-associated antigen genes

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7 January 2021

The LDL receptor gene: a mosaic of exons shared with different proteins

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7 January 2021

Relationships between the gene and protein structure in human complement component C9.

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7 January 2021

The neural cell adhesion molecule L1: genomic organisation and differential splicing is conserved between man and the pufferfish Fugu

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7 January 2021

Characterization of the human properdin gene

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7 January 2021

Structure of the chicken link protein gene: exons correlate with the protein domains

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7 January 2021

Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons

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7 January 2021

Complete structure of the chicken alpha 2(VI) collagen gene

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7 January 2021

Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution

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7 January 2021

Comparison of the whey acidic protein genra of the rat and mouse

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7 January 2021

Isolation and sequence of a human gene encoding a potent inhibitor of leukocyte proteases

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7 January 2021

Structure of the human hemopexin gene and evidence for intron-mediated evolution

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7 January 2021

The genomic structure of human BTK, the defective gene in X-linked agammaglobulinemia.

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7 January 2021

DNA sequence encoding the amino-terminal region of the human c-src protein: implications of sequence divergence among src-type kinase oncogenes

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7 January 2021

Human cellular src gene: nucleotide sequence and derived amino acid sequence of the region coding for the carboxy-terminal two-thirds of pp60c-src

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7 January 2021

Structure of the human laminin gamma 2 chain gene (LAMC2): alternative splicing with different tissue distribution of two transcripts

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7 January 2021

Identifiers

DOI

10.1038/88084

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28 June 2017

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